| Registry | NCT07360821, acronym ANS Stress/PA |
|---|---|
| Status | Not yet recruiting |
| Study type | Observational |
| Enrollment | 60 (Estimated) |
| Sponsor | Beijing Sport University (Other) |
| Conditions | Autonomic Nervous System Activity, Cardiovascular, Physical Activity Level |
| Interventions | Cardiopulmonary Exercise Testing (Diagnostic test) |
| Dates | start 2026-02-25 (estimated), primary completion 2026-04-30 (estimated), completion 2026-07-30 (estimated), first posted 2026-01-22, last updated 2026-01-22 |
Related Papers Related Patents Related Grants Related Experts
All trials for Autonomic Nervous System Activity All trials for Cardiovascular All trials of Cardiopulmonary Exercise Testing
This study aims to investigate the differences in cardiovascular stress response patterns among individuals with various physical activity levels (sedentary controls and different types of athletes). By synchronously monitoring ECG, heart rate, skin sympathetic nerve activity (SKNA), blood pressure, and cardiac output, the study will characterize physiological dynamics during resting, orthostatic challenge, cold pressor stress, and maximal exercise.
Participants will be categorized into five groups based on their training background: sedentary, endurance, strength, technical, and traditional ethnic sports. The experimental protocol includes baseline measurements in lying, standing, and sitting positions, followed by a series of acute stress tests: a lie-to-stand orthostatic test, a slow breathing test, and a cold pressor test. Finally, participants will perform a ramp incremental exercise test on a cycle ergometer. Synchronous physiological data including HRV and SKNA will be collected to evaluate the dynamic regulation of the autonomic nervous system.
| Arm | Type | Interventions | Description |
|---|---|---|---|
| Sedentary Control | Diagnostic Test: Cardiopulmonary Exercise Testing | Healthy adults with minimal physical activity, screened via SBQ and IPAQ-S questionnaires as baseline controls | |
| Endurance Athletes | Diagnostic Test: Cardiopulmonary Exercise Testing | Long-distance runners or triathletes with over 1 year of regular aerobic training (e.g., 800m+ running, swimming). | |
| Strength Athletes | Diagnostic Test: Cardiopulmonary Exercise Testing | Athletes specializing in anaerobic/power-based training, such as weightlifting, wrestling, or sprinting. | |
| Traditional Ethnic Sports | Diagnostic Test: Cardiopulmonary Exercise Testing | Practitioners of mind-body exercises like Tai Chi or Baduanjin, emphasizing respiratory control and mild intensity |
Sex: All, ages: 18 Years to 30 Years, accepts healthy volunteers
Inclusion Criteria: Healthy young adults aged 18-25 years Body Mass Index (BMI) within the range of 18.5-23.9 kg/m 2 No history of systematic professional athletic training (for sedentary group) or confirmed training background (for athlete groups) No exercise contraindications or history of cardiovascular, respiratory, or metabolic diseases No family history of sudden cardiac death Ability to understand the study protocol and sign the informed consent form Exclusion Criteria: History of limb sports injury within the past 6 months or unhealed fractures Habits of smoking or chronic alcohol consumption Presence of implanted electronic devices (e.g., pacemakers) Clinical diagnosis of psychiatric disorders such as anxiety or depression Recent use of medications affecting autonomic or cardiovascular function Regular practice of meditation or ongoing psychotherapy Irregular menstrual cycles (for female participants) Peripheral neuropathy or other autonomic nervous system disorders