Comparative Study of Muscle Transplantation Versus Y Splitting Recession Technique in Treatment of Large Angle Exotropia

NCT07350330 — Not applicable, Recruiting, 30 participants, Ain Shams University

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Registry	NCT07350330
Status	Recruiting
Phase	Not applicable
Study type	Interventional; randomized, parallel, masking: none, treatment
Enrollment	30 (Estimated)
Sponsor	Ain Shams University (Other)
Conditions	Exotropia
Interventions	muscle transplantation, Y splitting (Procedure)
Dates	start 2025-10-30, primary completion 2026-10-01 (estimated), completion 2026-12-30 (estimated), first posted 2026-01-20, last updated 2026-01-20
Locations	1 site in Egypt

-Summary

This study is designed to correct large-angle exotropia by monocular surgery. It compares two augmented recession techniques, which are recession with muscle transplantation and recession with Y splitting.

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+Arms and interventions

Arm	Type	Interventions	Description
Muscle transplantation	Active comparator	Procedure: muscle transplantation	This group will undergo medial rectus resection, lateral rectus recession, with muscle transplantation
Y splitting	Active comparator	Procedure: Y splitting	This group will undergo medial rectus resection, lateral rectus recession, with Y splitting

muscle transplantation (Procedure): transplanting a resected part of medial rectus to the already recessed lateral rectus muscle
Y splitting (Procedure): Y splitting of the recessed lateral rectus muscle

+Outcome measures

Primary outcomes

Ocular alignment [from the operation till six months postoperatively]: To measure ocular alignment using prisms after lateral rectus recession with muscle transplantation versus lateral rectus recession with Y splitting

Secondary outcomes

palpebral fissure height [from preoperative to 6 months postoperative]: Assess whether this is a change in palpebral fissure height pre- and postoperatively by measurement using a ruler
ocular incomitance [from surgery till 6 months afterward]: The presence of ocular incomitance and gaze restriction using prisms and motility tests after surgery

+Eligibility

Sex: All, ages: 6 Years to any

Inclusion Criteria:

* Age should be of more than 6 years Exotropia of an angle ranging from 50 to 70 PD Myopic or hypermetropic refraction

Exclusion Criteria:

* history of previous squint surgery significant vertical deviation incomitant squint in the form of paralytic or restrictive disorder any neurological disease

+Locations (1)

Facility	City	Country	Status
Ain shams university	Cairo	Egypt	Recruiting