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The Aim of the Study is to Examine the Variation in Blood Pressure Between an Optimal Measurement (According to Established Guidelines in the Literature - Per Guidelines) and a 'Common' Measurement (Used by Nursing Teams - Per Common Practice) Among Women of Reproductive Age With and Without Hyperte

NCT07320339 — Not applicable, Recruiting, 500 participants, Hillel Yaffe Medical Center

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Standard vs. Routine Blood Pressure Measurement in Pregnancy: Effects of Position and Diurnal Variation

RegistryNCT07320339
StatusRecruiting
PhaseNot applicable
Study typeInterventional; na, single group, masking: none, screening
Enrollment500 (Estimated)
SponsorHillel Yaffe Medical Center (Other gov)
ConditionsBlood Pressure Measurement in Pregnancy
Interventionsblood pressure measurement (Procedure)
Datesstart 2025-08-24, primary completion 2026-08-24 (estimated), completion 2026-08-24 (estimated), first posted 2026-01-06, last updated 2026-01-06
Locations1 site in Israel

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-Summary

The aim of the study is to examine the variation in blood pressure between an optimal measurement (according to established guidelines in the literature - per guidelines) and a 'common' measurement (used by nursing teams - per common practice) among women of reproductive age with and without hyperte

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+Detailed description

Accurate blood pressure measurement is a cornerstone of the diagnosis and management of hypertension. The latest Clinical Practice Guidelines (AHA2020- International Society of Hypertension Global) emphasize several important steps for accurate blood pressure measurement, including choosing the correct cuff size, resting for five minutes, sitting with support for the back, feet flat on the floor, and legs uncrossed, and proper arm positioning (i.e., positioning the midpoint of the cuff at heart level with the arm supported on a table or work surface). Sitting measurements are preferred because of the large amount of data linking blood pressure measurements in this position to health outcomes.

+Arms and interventions

ArmTypeInterventionsDescription
variation in blood pressure between an optimal measurement and a 'common' measurementExperimentalProcedure: blood pressure measurement
  • blood pressure measurement (Procedure): examine the variation in blood pressure between an optimal measurement (according to established guidelines in the literature - per guidelines) and a 'common' measurement (used by nursing teams - per common practice) among women of reproductive age with and without hypertention

+Outcome measures

Primary outcomes

  • Mean difference in systolic blood pressure (mmHg) between guideline-based and routine clinical measurement [1 year]: Mean difference in systolic blood pressure (mmHg) between guideline-based and routine clinical measurement Description: Systolic blood pressure (SBP) will be measured in each participant using two methods: 1. guideline-based blood pressure measurement performed according to international hypertension guidelines (seated position, appropriate cuff size, arm supported at heart level after ≥5 minutes of rest), and 2. routine clinical blood pressure measurement as performed by nursing staff under usual clinical conditions. The primary outcome will be the within-participant mean difference in SBP (mmHg) between the two measurement methods.

Secondary outcomes

  • Mean difference in diastolic blood pressure (mmHg) between guideline-based and routine clinical measurement [1 year]: As above, for diastolic blood pressure (DBP).
  • Mean difference in mean arterial pressure (mmHg) between guideline-based and routine clinical measurement [1 yaer]: Mean arterial pressure (MAP) will be calculated as MAP = (SBP + 2×DBP) / 3 for each measurement method. The outcome will be the within-participant difference between methods

+Eligibility

Sex: Female, ages: 18 Years to 40 Years, accepts healthy volunteers

Inclusion Criteria:

* Women aged 18-40
* Informed consent to participate.

Exclusion Criteria:

* Inability to cooperate with BP measurement under optimal conditions
* Women with complex underlying disease that may bias the data (e.g. significant vasculopathy)

+Locations (1)

FacilityCityCountryStatus
Hille Yaffe Medical CenterHadera, IsraelIsraelRecruiting

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