Comparison of Advanced Platelet Rich Fibrin Versus Platelet Rich Fibrin as a Gap Filling Material in Immediate Implant Placement
| Registry | NCT07319494, acronym A-PRF vs PRF |
|---|---|
| Status | Active not recruiting |
| Phase | Not applicable |
| Study type | Interventional; randomized, parallel, masking: none, treatment |
| Enrollment | 16 (Actual) |
| Sponsor | Beni-Suef University (Other) |
| Conditions | Comparison of Advanced Platelet-Rich Fibrin Versus Platelet-Rich Fibrin as a Gap-filling Material |
| Interventions | Immediate Dental Implant and A-PRF, Immediate dental implant and PRF (Procedure) |
| Dates | start 2025-06-25, primary completion 2025-11-26, completion 2026-02-15 (estimated), first posted 2026-01-06, last updated 2026-01-06 |
| Locations | 1 site in Egypt |
Related Papers Related Patents Related Grants Related Experts
All trials for Comparison of Advanced Platelet-Rich Fibrin Versus Platelet-Rich Fibrin as a Gap-filling Material All trials of Immediate Dental Implant and A-PRF All trials of Immediate dental implant and PRF
Study type: Clinical Trial
Goal:
The goal of this clinical trial is to learn if Advanced Platelet-Rich Fibrin (A-PRF) versus traditional Platelet-Rich Fibrin (PRF) can improve bone healing and soft tissue outcomes in patients undergoing immediate dental implant placement.
Main questions it aims to answer:
Does A-PRF provide greater buccal bone preservation compared to PRF after immediate implant placement?
Does A-PRF improve soft tissue healing and reduce postoperative complications compared to PRF?
Comparison group:
Researchers will compare A-PRF to PRF as a gap-filling material in immediate implants to see if A-PRF results in better bone and soft tissue outcomes.
Participants will:
Undergo tooth extraction followed by immediate implant placement
Receive either A-PRF or PRF as the gap-filling material in the implant site
Have CBCT scans at baseline and 6 months to measure bone thickness
Have clinical assessments of soft tissue healing and implant stability
Attend follow-up visits at 1 week, 1 month, 3 months, and 6 months post-surgery
| Arm | Type | Interventions | Description |
|---|---|---|---|
| PRF Group | Experimental | Procedure: Immediate dental implant and PRF | Participants in this arm will undergo tooth extraction followed by immediate implant placement. The extraction socket will be filled with traditional Platelet-Rich Fibrin (PRF) as the gap-filling material. |
| A-PRF Group | Experimental | Procedure: Immediate Dental Implant and A-PRF | Participants in this arm will undergo tooth extraction followed by immediate implant placement. The extraction socket will be filled with Advanced Platelet-Rich Fibrin (A-PRF) as the gap-filling material. |
Sex: All, ages: 20 Years to any
Inclusion Criteria: * The selected patients has a badly decayed mandibular posterior teeth which are indicated for extraction due to dental causes (periapical abscess, trauma or caries) not periodontal as diagnosed by periapical x-ray. * Healthy patients who are classified according to the American Society of Anesthesiologists (ASA)(2022) physical status classification as class I. * Patient age ≥ 20 years old. * Surgical site with sufficient for implant placement. * Sufficient interocclusal space for prosthesis. * Good oral hygiene. * Patients have thick biotype. * Patients have socket class I. Exclusion Criteria: * Active periodontal diseases and periapical lesions not chronic infections. * Patients have parafunctional * History of alcohol or drug dependency, psychological factor that might affect the surgical or prosthodontic treatment. * Smoking. * Pregnant patients. * Patients who are not willing to complete the study.
| Facility | City | Country | Status |
|---|---|---|---|
| Delta University For Science And Technology | Al Mansurah | Egypt |