IWS Diagnosis Criteria Consensus

NCT07316894 — Recruiting, 120 participants, ELIAS Emergency University Hospital

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International Delphi Consensus on the Universal Definition and Diagnosis of Iatrogenic Withdrawal Syndrome in Adult ICU Patients

Registry	NCT07316894
Status	Recruiting
Study type	Observational
Enrollment	120 (Estimated)
Sponsor	ELIAS Emergency University Hospital (Other); collaborators: University of Rome Tor Vergata, Boston University, Carol Davila University of Medicine and Pharmacy
Conditions	Iatrogenic Withdrawal Syndrome
Interventions	ICU, Anesthesiology and Psychiatry specialists consensus on the diagnosis of IWS. (Other)
Dates	start 2025-12-13, primary completion 2026-03-31 (estimated), completion 2026-05-01 (estimated), first posted 2026-01-05, last updated 2026-01-05
Locations	1 site in Romania

-Summary

This is an International Delphi Consensus on the Definition and Diagnosis of Iatrogenic Withdrawal Syndrome in adult critically ill patients. It involves the anonymous completion of a questionnaire using a 7-point Likert scale.

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+Arms and interventions

ICU, Anesthesiology and Psychiatry specialists consensus on the diagnosis of IWS. (Other): This is a new and originally developed questionnaire comprising of 19 questions. Out of 19 questions, 17 use a 7-point Likert scale response, one uses a Yes/No type of answer and one has open answers.

+Outcome measures

Primary outcomes

Diagnostic Criteria of IWS [4 monts]: The diagnostic criteria of IWS will be determined based on the items reaching the consensus

+Eligibility

Sex: All

Inclusion Criteria:

* At least 5 years of experience or training or research in the field of Intensive Care Medicine, Anesthesiology or Psychiatry

Exclusion Criteria:

* Not a specialist in the fields of Intensive Care Medicine, Anesthesiology or Psychiatry

+Locations (1)

Facility	City	Country	Status
Elias Emergency University Hospital	Bucharest	Romania	Recruiting

+Publications

Moisa E, Tuculeanu G, Corneci D, Negoita SI, Bilotta F. Iatrogenic withdrawal syndrome in adult intensive care unit: a scoping review. Front Med (Lausanne). 2025 Jul 23;12:1573363. doi: 10.3389/fmed.2025.1573363. eCollection 2025. PMID 40771468

+Investigators

Emanuel Moisa, Assist. Prof., MD, PhD, DESAIC, Principal investigator, Elias Emergency University Hospital of Bucharest, Carol Davila University of Medicine and Pharmacy, Bucharest
Federico Bilotta, Professor, MD, PhD, Study chair, Tor Vergata University of Rome