TrialReader


Minimally Invasive Suprachoroidal Drainage for the Treatment of Neovascular Glaucoma

NCT07201415 — Not applicable, Active not recruiting, 30 participants, Zhongnan Hospital

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  

An Exploratory Study of the Efficacy and Safety of Minimally Invasive Supraporoidal Drainage for Advanced Neovascular Glaucoma

RegistryNCT07201415
StatusActive not recruiting
PhaseNot applicable
Study typeInterventional; na, single group, masking: none, treatment
Enrollment30 (Estimated)
SponsorZhongnan Hospital (Other)
ConditionsNeovascular Glaucoma
Interventionsminimally invasive suprachoroidal drainage (Procedure)
Datesstart 2025-01-01, primary completion 2026-12-31 (estimated), completion 2027-03-01 (estimated), first posted 2025-10-01, last updated 2025-10-01
Locations1 site in China

Related Papers Related Patents Related Grants Related Experts
AI Assistant Save
All trials for Neovascular Glaucoma All trials of minimally invasive suprachoroidal drainage

-Summary

To explore the efficacy and safety of minimally invasive suprachoroidal drainage for the treatment of advanced neovascular glaucoma

Expand all sections  ·  Collapse all

+Detailed description

To explore the efficacy and safety of minimally invasive supraporcular drainage in the treatment of advanced neovascular glaucoma, and to record the various basic diseases, ocular conditions, lifestyle, inflammatory markers and other parameters of NVG patients. To compare the safety and efficacy of new surgical methods and traditional surgical methods in order to find an effective treatment for neovascular glaucoma

+Arms and interventions

ArmTypeInterventionsDescription
Surgical Treatment GroupExperimentalProcedure: minimally invasive suprachoroidal drainageThe patient will undergo a minimally invasive suprachoroidal drainage procedure
  • minimally invasive suprachoroidal drainage (Procedure): minimally invasive suprachoroidal drainage

+Outcome measures

Primary outcomes

  • Ocular biological parameters [1 day, 1 week, 1 month, 3 months, and 6 months after surgery]: intraocular pressure
  • Ocular biological parameters [1 day, 1 week, 1 month, 3 months, and 6 months after surgery]: visual acuity
  • Surgical outcome measures [1 day, 1 week, 1 month, 3 months, and 6 months after surgery]: use of intraocular pressure lowering drugs
  • The success rate of surgery was evaluated according to the specific value of intraocular pressure after surgery [1 day, 1 week, 1 month, 3 months, and 6 months after surgery]: Complete success was defined as IOP within the normal range with no drug dependence, conditional success was defined as IOP within the normal range with drug dependence, and failure was defined as the rest

Secondary outcomes

  • The effective rate of surgery was evaluated according to the amplitude of IOP reduction after surgery and the change in the number of IOP-lowering drugs [1 day, 1 week, 1 month, 3 months, and 6 months after surgery]: Amplitude of IOP reduction: IOP change/initial IOP.The total number of IOP lowering drugs was recorded based on the number of active ingredients
  • Surgical outcome measures [1 day, 1 week, 1 month, 3 months, and 6 months after surgery]: complications

+Eligibility

Sex: All, ages: 18 Years to 85 Years

Inclusion Criteria:

* Advanced (angle-closure) neovascular glaucoma with poorly controlled intraocular pressure (IOP > 21mmHg) after medical or surgical treatment

Exclusion Criteria:

* Various other types of glaucoma (including primary open-angle glaucoma, primary open-closed glaucoma, normal tension glaucoma, juvenile glaucoma, congenital glaucoma, other special types of glaucoma, etc.)
* Eye infection within two weeks before surgery
* Non-glaucomatous intraocular diseases that affect intraocular pressure (choroidal hemorrhage or detachment, retinal detachment, lens subluxation, thyroid eye disease, clinically significant macular edema, eye tumors, etc.)
* Visual acuity of non-study eyes < 0.05
* Congenital or acquired factors lead to ciliary body anatomical abnormalities

+Locations (1)

FacilityCityCountryStatus
Zhongnan Hospital of Wuhan UniversityWuhan, HubeiChina

My Notes