"From One Problem to Another, Comparing the Incidence of Compensatory Hyperhidrosis After T3 Vs. T3-4 Sympathectomy"
| Registry | NCT07196319 |
|---|---|
| Status | Not yet recruiting |
| Study type | Observational |
| Enrollment | 46 (Estimated) |
| Sponsor | Assiut University (Other) |
| Conditions | Compensatory Hyperhidrosis, Compensatory Sweating |
| Dates | start 2025-11-15 (estimated), primary completion 2027-10-20 (estimated), completion 2028-10-25 (estimated), first posted 2025-09-29, last updated 2025-10-03 |
Related Papers Related Patents Related Grants Related Experts
AI Assistant Save
All trials for Compensatory Hyperhidrosis All trials for Compensatory Sweating
The goal of this study is to compare the proportion of compensatory hyperhidrosis patients after sympathectomy at T3 level and sympathectomy at T3-4 level. The main question it aims to answer is:
can sympathectomyv at one level decrease the incidence of compensatory hyperhidrosis after primary hyperhidrosis.
Primary hyperhidrosis is a chronic condition characterized by excessive sweating beyond physiological needs, commonly affecting the palms, axillae, face, or soles. This disorder is largely attributed to neurogenic hyperexcitability within the sympathetic nervous system's pathways innervating the eccrine sweat glands.When conservative treatments such as topical agents or oral medications fail, endoscopic thoracic sympathectomy (ETS) is considered an effective surgical option. However, a major postoperative complication is compensatory hyperhidrosis (CH)-the development of excessive sweating in previously unaffected areas such as the trunk, back, or thighs. CH can significantly impact patient satisfaction and quality of life, often becoming more distressing than the original condition.
The extent and level of sympathectomy have been proposed as key factors influencing the incidence and severity of CH. While higher levels or multilevel resections (e.g., T2-4) are associated with increased rates of CH, more limited approaches such as T3-only resection are thought to reduce this risk. However, definitive evidence comparing T3 versus T3-4 sympathectomy remains limited and inconsistent across studies.
This study aims to compare the incidence and severity of compensatory hyperhidrosis following T3 versus T3-4 sympathectomy for primary hyperhidrosis. Understanding these differences may help refine surgical approaches to minimize CH and improve patient outcomes.
| Arm | Type | Interventions | Description |
|---|---|---|---|
| T3 sympathectomy | patients who underwent T3 sympathectomy for primary hyperhidrosis | ||
| T3-4 sympathectomy | patients who underwent through T3-4 sympathectomy for primary hyperhidrosis |
Sex: All, ages: 6 Years to any
Inclusion Criteria: * Patients diagnosed with primary hyperhidrosis * Patients with palmar and\\or axillary hyperhidrosis. * Age ≥ 6 years Exclusion Criteria: * History of Prior thoracic surgery. * History of prior disorder that cause hyperhidrosis ( obesity,autonomic neuropathy,menopause,gout,etc…) * History of prior systemic diseases cause hyperhidrosis (hyperthyroidism,DM,pheochromocytoma,Parkinson's disease,etc…) * Patients with psychological problems.