PITCH - Impacting Hereditary Cancer Testing

NCT07090109 — Not applicable, Not yet recruiting, 200 participants, Rachel Miller

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Partnering to Impact Testing in the Commonwealth for Hereditary Cancers (PITCH)

Registry	NCT07090109
Status	Not yet recruiting
Phase	Not applicable
Study type	Interventional; na, single group, masking: none, other
Enrollment	200 (Estimated)
Sponsor	Rachel Miller (Other)
Conditions	Ovarian Cancer, Genetic Testing, Genetic Counseling
Interventions	Genetic testing education video (Behavioral)
Dates	start 2027-04-01 (estimated), primary completion 2027-07-01 (estimated), completion 2027-07-01 (estimated), first posted 2025-07-29, last updated 2026-09-10
Locations	1 site in United States

-Summary

The goal of this clinical trial is to assess patients' knowledge and attitudes about genetic testing before and after viewing an educational video. The main questions it aims to answer are:

* Did the video change participants' knowledge and attitudes about genetic testing?
* Did participants make an informed choice about pursuing genetic testing?

Participants will:

* Complete a baseline survey
* View educational video
* Complete follow-up survey

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+Arms and interventions

Arm	Type	Interventions	Description
Educational Video	Experimental	Behavioral: Genetic testing education video	Participants will complete a survey before and after viewing an educational video

Genetic testing education video (Behavioral): patient education video about genetic testing for hereditary cancers

+Outcome measures

Primary outcomes

Change in Multi-Dimensional Measure of Informed Choice (MMIC) - Cancer Knowledge Scale [Baseline and post intervention (approximately 30 minutes)]: The MMIC is a compound assessment tool with three elements which are used together to differentiate an informed choice from a less informed choice. An informed choice is demonstrated by: Achieving =75% (6 of 8 questions) correct responses on the knowledge scale AND Making a decision that is in keeping with one's values related to the outcome (positive vs. negative) A less informed choice is demonstrated by: Achieving <75% correct responses on the knowledge scale OR Achieving =75% correct responses on the knowledge scale but making a decision that is inconsistent with one's values (e.g., a patient values the information that may be obtained but chose not to undergo testing OR a patient does not value the information and chose to undergo testing)

Secondary outcomes

Number of participants completing genetic testing [90 days]: Number of participants that complete testing after the intervention

+Eligibility

Sex: Female, ages: 18 Years to any

Inclusion Criteria:

* diagnosed with a cancer that can be associated with hereditary forms of cancer

Exclusion Criteria:

* previously undergone multi-gene panel testing for hereditary cancers

+Locations (1)

Facility	City	Country	Status
University of Kentucky	Lexington, Kentucky	United States

+Investigators

Rachel Miller, MD, Principal investigator, University of Kentucky