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Rhomboid Intercostal and Subserratus Plane Block vs Erector Spinae Plane Block in Video-Assisted Thoracoscopic Surgery

NCT07011069 — Not applicable, Completed, 93 participants, Bursa City Hospital

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Comparison of the Efficacy of Rhomboid Intercostal and Subserratus Plane Block (RISS) Versus Erector Spinae Plane (ESP) Blocks in Video-Assisted Thoracoscopic Surgery (VATS) for Postoperative Pain Management and Respiratory Function

RegistryNCT07011069
StatusCompleted
PhaseNot applicable
Study typeInterventional; randomized, parallel, masking: triple, treatment
Enrollment93 (Actual)
SponsorBursa City Hospital (Other gov)
ConditionsVideo Assisted Thoracoscopic Surgery, Regional Block for Pain Control, Regional Blocks, Pulmonary Functions
InterventionsESP block group, RISS block group (Procedure)
Datesstart 2025-06-09, primary completion 2025-12-04, completion 2025-12-15, first posted 2025-06-08, last updated 2026-09-24
Locations1 site in Turkey (Türkiye)

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-Summary

To compare the rhomboid intercostal subserratus plane block with the erector spinae plane block regarding their analgesic efficacy and effects on respiratory function for patients undergoing video-assisted thoracoscopic surgery.

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+Detailed description

Video-assisted thoracoscopic surgery (VATS) can be very painful and may lead to complications such as prolonged stays in intensive care, thromboembolic complications due to lack of early mobilization, chronic acute pain, and delirium if adequate analgesia is not provided. Therefore, using thoracic epidural, paravertebral, or regional blocks as part of multimodal analgesia is recommended to provide effective pain relief.

This study aims to compare the effects of the erector spinae plane block (ESP) and rhomboid intercostal subserratus plane block (RISS) on postoperative analgesia and the improvement of respiratory parameters in patients undergoing VATS. These two techniques may have different analgesic profiles with respect to somatic and visceral pain.

The primary objective is to evaluate the incidence of chest tube-site somatic pain at postoperative hour 2. Secondary objectives include the incidence of visceral pain, total analgesic consumption in the first 24 hours postoperatively, assessing resting and dynamic pain scores, triflow performance, complications, and length of hospital stay.

+Arms and interventions

ArmTypeInterventionsDescription
Patients who received ESP blockActive comparatorProcedure: ESP block groupThose who received the erector spinae plane block for postoperative pain management
Patients who received RISS blockActive comparatorProcedure: RISS block groupThose who received the rhomboid intercostal subserratus plane block for postoperative pain management
  • ESP block group (Procedure): ESP blocks are performed for patients undergoing VATS.
  • RISS block group (Procedure): RISS blocks are performed for patients undergoing VATS.

+Outcome measures

Primary outcomes

  • Incidence of chest tube-site somatic pain [At postoperative hour 2]: Proportion of participants with localized pain at the chest tube insertion site, elicited by palpation or chest tube manipulation. Somatic pain was recorded as present or absent.

Secondary outcomes

  • Dynamic pain score [Postoperative first 24 hours.]: Postoperative pain scores during coughing and deep breathing are measured on a 11 cm scale, where "0" indicates no pain and "10" indicates the worst pain ever.
  • Opioid consumption [Postoperative first 24 hours.]: Total opioid consumption within the first 24 hours in the postoperative period.
  • Resting pain score [Postoperative first 24 hours.]: Postoperative pain scores during rest are measured on a 11 cm scale, where "0" indicates no pain and "10" indicates the worst pain ever.
  • Pulmonary functions [Postoperative first 24 hours.]: Pulmonary functions are assessed using Triflow performance. Postoperative Triflow numbers (whether 1, 2, or 3 balls can be raised) for the patients are recorded.
  • Complications [From block administration to hospital discharge.]: Complications regarding regional blocks and surgery (such as hematoma, pulmonary complications) are recorded.
  • Hospital stay time [From surgery to hospital discharge.]: The length of hospital stay is recorded.
  • Incidence of visceral pain [At postoperative hour 2]: Proportion of participants reporting deep, poorly localized intrathoracic pain not confined to the incision or chest tube insertion site. Pain was recorded as present or absent.

+Eligibility

Sex: All, ages: 18 Years to 80 Years

Inclusion Criteria:

* Patients who will undergo VATS
* Who agrees to participate
* American Society of Anesthesiologists (ASA) physical status I, II, and III
* Elective surgery
* Age between 18 and 80 years

Exclusion Criteria:

* Local anesthetic allergy
* Who disagrees to participate
* ASA physical status IV and V
* Emergency surgery
* Hemorrhagic disease
* Thoracic vertebrae deformity
* Thoracic vertebrae surgery

+Locations (1)

FacilityCityCountryStatus
University of Health Sciences, Bursa City HospitalBursa, NiluferTurkey (Türkiye)

+Publications

  • Forero M, Rajarathinam M, Adhikary S, Chin KJ. Erector spinae plane (ESP) block in the management of post thoracotomy pain syndrome: A case series. Scand J Pain. 2017 Oct;17:325-329. doi: 10.1016/j.sjpain.2017.08.013. Epub 2017 Sep 12. PMID 28919152
  • Elsharkawy H, Maniker R, Bolash R, Kalasbail P, Drake RL, Elkassabany N. Rhomboid Intercostal and Subserratus Plane Block: A Cadaveric and Clinical Evaluation. Reg Anesth Pain Med. 2018 Oct;43(7):745-751. doi: 10.1097/AAP.0000000000000824. PMID 30169476
  • Hsieh MJ, Wang KC, Liu HP, Gonzalez-Rivas D, Wu CY, Liu YH, Wu YC, Chao YK, Wu CF. Management of acute postoperative pain with continuous intercostal nerve block after single port video-assisted thoracoscopic anatomic resection. J Thorac Dis. 2016 Dec;8(12):3563-3571. doi: 10.21037/jtd.2016.12.30. PMID 28149550

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