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Comparing Two Eccentric Protocols on Muscle Damage

NCT06992271 — Not applicable, Recruiting, 16 participants, New York Institute of Technology

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A Novel Eccentric Resistance Training Strategy to Maximize Exercise Induced Muscle Damage in Young Adults

RegistryNCT06992271
StatusRecruiting
PhaseNot applicable
Study typeInterventional; randomized, crossover, masking: none, basic science
Enrollment16 (Estimated)
SponsorNew York Institute of Technology (Other)
ConditionsEccentric Hypertrophy, Muscle Damage
InterventionsFast Eccentric, Slow Eccentric (Behavioral)
Datesstart 2023-03-08, primary completion 2025-06-01 (estimated), completion 2025-06-01 (estimated), first posted 2025-05-28, last updated 2025-05-28
Locations1 site in United States

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-Summary

The purpose of this study will be to test whether a new way of weight training is more effective than typical weight training. The investigators expect that this new way will cause more exercise-induced muscle damage, which helps people build bigger muscles. Another purpose of this study will be to explore perceptions of how muscle soreness impacts participant activities of daily living.

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+Detailed description

Participants will come to the lab for 3 sessions, plus two email follow-up questionnaires.

Session 1 (45 minutes)

* Complete a demographic questionnaire
* Self-assess muscle soreness
* Walk on the treadmill to warm-up
* Maximal voluntary contraction on the chest press
* Two sets of eccentric (lowering) bench press at 75% of max

Session 2 (45 minutes)

* Walk on the treadmill to warm up
* Maximal voluntary contraction on the chest press
* Three sets of 10 eccentric contractions at 75% of max
* Repeat the maximal voluntary contraction on the chest press

Session 2 Follow-up Rate muscle soreness for each of the three days following Session 2 Answer open-ended questions about perceptions of the muscle soreness

Session 3 (45 minutes) Walk on the treadmill to warm up Maximal voluntary contraction on the chest press Three sets of 10 eccentric contractions at 75% of max Repeat the maximal voluntary contraction on the chest press

Session 3 Follow-up Rate muscle soreness for each of the three days following Session 2 Answer open-ended questions about perceptions of the muscle soreness

+Arms and interventions

ArmTypeInterventionsDescription
Fast EccentricExperimentalBehavioral: Fast EccentricParticipants will perform fast eccentric resistance training
Slow eccentricActive comparatorBehavioral: Slow EccentricParticipants will perform slow eccentric resistance training
  • Fast Eccentric (Behavioral): Resistance training done quickly
  • Slow Eccentric (Behavioral): Resistance training done slowly

+Outcome measures

Primary outcomes

  • Muscle soreness 1 [1 day]: Visual analog scale as indirect indicator of muscle damage. Scale of 1-5. Higher score = more soreness
  • Muscle soreness 2 [2 days]: Visual analog scale as indirect indicator of muscle damage. Scale of 1-5. Higher score = more soreness
  • Muscle soreness 3 [3 days]: Visual analog scale as indirect indicator of muscle damage. Scale of 1-5. Higher score = more soreness
  • Maximal Voluntary Isometric Contraction Change [pre-intervention, immediately after the intervention]: Change in MVIC will be used to indicated muscle damage.

+Eligibility

Sex: All, ages: 18 Years to 35 Years, accepts healthy volunteers

Inclusion Criteria:

* Sixteen young adults (ages 18-35) will be enrolled in this study.
* In order to be enrolled, they must have completed at least three months of resistance training in the past five years in order to minimize the learning effect and chance of injury.

Exclusion Criteria:

* Since regular resistance training reduces the primary outcomes, muscle damage and soreness, individuals who currently participate in chest press resistance training at least once per week will be excluded.
* Individuals who have musculoskeletal injuries in the shoulder, elbow or wrist that preclude pain-free resistance training, or who have underlying uncontrolled cardiovascular complications will also be excluded.
* Women who are pregnant, or may consider becoming pregnant over the subsequent 2 months, will be excluded

+Locations (1)

FacilityCityCountryStatus
NYITOld Westbury, New YorkUnited StatesRecruiting

+Investigators

My Notes