Evaluating Decision-making Using ChatGPT-4 Among Trainees in Surgery

NCT06921447 — Not yet recruiting, 35 participants, Ospedali Riuniti Trieste

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Evaluating ChatGPT-4 as a Decision-Making Support Tool for Surgical Trainees

RegistryNCT06921447, acronym EDuCATe
StatusNot yet recruiting
Study typeObservational
Enrollment35 (Estimated)
SponsorOspedali Riuniti Trieste (Other)
ConditionsArtificial Intelligence (AI), Training, Surgery
InterventionsClinical Cases (Other)
Datesstart 2025-04-10 (estimated), primary completion 2025-04-25 (estimated), completion 2025-04-30 (estimated), first posted 2025-04-10, last updated 2025-04-10
Locations1 site in Italy

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-Summary

This study aims to assess whether ChatGPT-4 can support surgical trainees in clinical decision-making. By comparing the performance of ChatGPT-4 with junior residents, senior residents, and attending surgeons on standardized clinical scenarios, the study seeks to understand the potential role of large language models in surgical education. The ultimate goal is to evaluate whether ChatGPT-4 can be safely integrated as a supplementary educational tool to aid junior residents in developing critical thinking and surgical judgment.

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+Detailed description

Background:

Artificial Intelligence (AI) is rapidly transforming the medical landscape, offering new possibilities in education, diagnostics, and decision support. In surgery, clinical decision-making is a core competency developed progressively through training. ChatGPT-4, a state-of-the-art large language model developed by OpenAI, has demonstrated competence in handling medical queries and clinical reasoning tasks. However, its performance in complex surgical decision-making compared to human trainees remains largely unexplored.

Objective:

The EDuCATe study aims to evaluate the accuracy and reliability of ChatGPT-4's responses to clinical scenarios involving general surgery cases. Specifically, the study compares the model's performance to that of junior residents, senior residents, and attending surgeons to understand if ChatGPT-4 can serve as a safe and effective educational tool for surgical trainees.

Methods:

Seven clinical scenarios will be constructed using real anonymized patient data representing common general surgery conditions. Each case will be presented step-by-step, mimicking the clinical decision-making process. Participants will answer a question related to treatment choice.

Participants will include junior residents (PGY1-2), senior residents (PGY3+), and attending surgeons from a single surgical department. ChatGPT-4 will be prompted with the same scenarios. All participants will be instructed to complete the cases without using external resources such as AI tools or internet searches, relying solely on their clinical knowledge.

Statistical analysis will compare performance across groups using non-parametric tests (e.g., Wilcoxon rank sum).

Expected Outcomes:

The study hypothesizes that ChatGPT-4 will perform at a level comparable to senior residents or attending surgeons and outperform junior residents in decision-making. If confirmed, these results could support the safe use of ChatGPT-4 as a training aid for junior surgical residents, potentially improving educational outcomes and clinical reasoning skills.

Significance:

This study will provide novel insight into the role of AI in surgical education. By rigorously comparing ChatGPT-4's decision-making capabilities to that of human surgeons at various levels, the study hopes to define its utility, limitations, and appropriate use in residency training programs.

+Arms and interventions

ArmTypeInterventionsDescription
ResidentsOther: Clinical CasesJunior and Senior Residents in General Surgery
ConsultantsOther: Clinical CasesSenior General Surgeons
ChatGPT 4Other: Clinical CasesArtificial Intelligence System
  • Clinical Cases (Other): Seven clinical cases that have to be analysed

+Outcome measures

Primary outcomes

  • Proportion of correct responses [Baseline]: Binary outcome (correct vs. incorrect decision)

Secondary outcomes

  • Comparison of accuracy across experience levels [Baseline]: Proportion of correct responses by group: Junior residents, Senior residents, Attending surgeons, ChatGPT-4
  • Confidence level [Baseline]: Participants and ChatGPT are asked to rate how confident they feel in their answer (1-5 Likert scale, where 1 means no confident and 5 very confident)
  • Percentage of use of AI for clinical cases evaluation [Baseline]: Participants are asked if they use or not ChatGPT in their clinical activity

+Eligibility

Sex: All

Inclusion Criteria:

* Actively enrolled or employed in the general surgery residency or department at the participating institution
* Willingness to participate and complete all clinical case scenarios
* Consent to participate in the study

Exclusion Criteria:

* Incomplete responses
* Use of external assistance (e.g., internet search, AI tools) when answering scenarios, as self-reported in instructions

+Locations (1)

FacilityCityCountryStatus
University of TriesteTriesteItaly