Effectiveness and Safety of 25-Gauge Needle-Assisted Phacoemulsification of Dislocated Intravitreal Lens Nucleus

NCT06709378 — Completed, 9 participants, Changzhou No.2 People's Hospital

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Registry	NCT06709378
Status	Completed
Study type	Observational
Enrollment	9 (Actual)
Sponsor	Changzhou No.2 People's Hospital (Other)
Conditions	Dislocated Lens, Pars Plana Vitrectomy, Phacoemulsification, Needle
Dates	start 2022-07-01, primary completion 2024-09-01, completion 2024-09-01, first posted 2024-11-29, last updated 2024-11-29
Locations	1 site in China

-Summary

The goal of this observational study is to learn about the effects of 25-gauge (G) needle-assisted phacoemulsification to remove dislocated intravitreal lens nuclei.

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+Detailed description

Patients with dislocated intravitreal lens nuclei who underwent 23G pars plana vitrectomy (PPV) and 25G needle-assisted phacoemulsification between July 2022 and September 2024 were included. Primary outcomes included best-corrected visual acuity (BCVA) and intraocular pressure (IOP). Secondary outcomes included corneal endothelial cell count (CECC) and the incidence of intraoperative and postoperative complications. These outcomes were statistically analyzed both preoperatively and postoperatively. A minimum follow-up of 6 months was completed for all eyes.

+Outcome measures

Primary outcomes

Best corrected visual acuity [Preoperatively and postoperatively for at least 6 months.]: Best corrected visual acuity was measured with logarithmic visual acuity chart.

Secondary outcomes

Intraocular pressure [Preoperatively and postoperatively for at least 6 months.]: Intraocular pressure was measured with noncontact tonometer.
Corneal endothelial cell count [Preoperatively and postoperatively for at least 6 months.]: Corneal endothelial cell count was measured with specular microscope.

+Eligibility

Sex: All

Inclusion Criteria:

Clinical diagnosis of dislocated intravitreal lens nuclei Signed informed consent

Exclusion Criteria:

Surgical contraindications

+Locations (1)

Facility	City	Country	Status
the Second People's Hospital of Changzhou	Changzhou, Jiangsu	China

+Publications

Results publication: Feng Q, Li Y, Jiang Y, Sun X. Effect of 25-Gauge Needle-Assisted Phacoemulsification of Dislocated Intravitreal Lens Nucleus. J Ophthalmol. 2026 May 27;2026:8429779. doi: 10.1155/joph/8429779. eCollection 2026. PMID 42211675

+Investigators

Xincheng Sun, Study director, Changzhou No.2 People's Hospital