Nostril Side on Epistaxis

NCT06605989 — Not applicable, Recruiting, 208 participants, Seoul National University Hospital

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The Effect of Nostril Side on Epistaxis During Nasotracheal Intubation

Registry	NCT06605989
Status	Recruiting
Phase	Not applicable
Study type	Interventional; randomized, parallel, masking: double, prevention
Enrollment	208 (Estimated)
Sponsor	Seoul National University Hospital (Other); collaborators: SMG-SNU Boramae Medical Center
Conditions	Nasotracheal Intubation
Interventions	Nasotracheal intubation (Procedure)
Dates	start 2024-09-26, primary completion 2026-02-28 (estimated), completion 2026-02-28 (estimated), first posted 2024-09-20, last updated 2026-02-11
Locations	2 sites in South Korea

-Summary

The purpose of the study is to investigate the effect of the nostril side on epistaxis during nasotracheal intubation.

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+Detailed description

This prospective randomized controlled study was approved by the IRB of our institute.

Patients requiring nasotracheal intubation will be screened for eligibility for the study. Then, patients will be randomized to one of two groups; (Group I: tube will be inserted through the left nostril and advanced into the oral cavity / Group II: tube will be inserted through the right nostril and advanced into the oral cavity). After induction of anesthesia and muscle relaxation, the preformed nasal RAE (Ring-Adair-Elwyn) tube will be inserted via the nostril, which is assigned to each patient according to the group, approximately 3-4 cm. Next, an anesthesiologist will advance the tube into the oral cavity. After the tube is placed in the oral cavity, the anesthesiologist will perform nasotracheal intubation with Magill forceps. After that, an investigator will check the occurrence of epistaxis due to nasotracheal intubation and its severity with a fiberoptic bronchoscope. After obtaining all data, investigators will analyze the incidence of epistaxis and its severity between the two groups.

+Arms and interventions

Arm	Type	Interventions	Description
left nostril side	Experimental	Procedure: Nasotracheal intubation	For nasotracheal intubation, the nasal RAE tube will be inserted through the left nostril and advanced into the oral cavity.
right nostril side	Experimental	Procedure: Nasotracheal intubation	For nasotracheal intubation, the nasal RAE tube will be inserted through the right nostril and advanced into the oral cavity.

Nasotracheal intubation (Procedure): For nasotracheal intubation, the nasal RAE tube will be first inserted through the left nostril for patients in the left nostril side arm. For nasotracheal intubation, the nasal RAE tube will be first inserted through the right nostril for patients in the right nostril side arm.

+Outcome measures

Primary outcomes

epistaxis [during nasotracheal intubation]: epistaxis due to nasotracheal intubation

+Eligibility

Sex: All, ages: 19 Years to any

Inclusion Criteria:

* adult patients requiring nasotracheal intubation for elective surgery

Exclusion Criteria:

* refuse to participate in the study
* severe deformity in the nose
* current severe epistaxis
* cannot insert the tube into a specific nostril side due to any reason

+Locations (2)

Facility	City	Country	Status
Seoul Metropolitan Government Seoul National University Boramae Medical Center	Seoul, Dongjak-gu	South Korea	Recruiting
Gangnam Severance Hospital	Seoul, Gangnam-gu	South Korea	Recruiting

+Publications

Sanuki T, Hirokane M, Kotani J. Epistaxis during nasotracheal intubation: a comparison of nostril sides. J Oral Maxillofac Surg. 2010 Mar;68(3):618-21. doi: 10.1016/j.joms.2009.04.097. Epub 2009 Nov 22. PMID 19931965

+Investigators

Jung-Man Lee, M.D.,Ph.D., Principal investigator, Seoul National University College of Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center