The Impact of Working Night Shifts on Cardiac Autonomic Nervous Regulation During the Six-minute Walk Test in Nurses

NCT06542510 — Completed, 35 participants, Nanfang Hospital, Southern Medical University

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  
RegistryNCT06542510
StatusCompleted
Study typeObservational
Enrollment35 (Actual)
SponsorNanfang Hospital, Southern Medical University (Other)
ConditionsAutonomic Nervous System Imbalance
Interventionsworking night shift (Behavioral)
Datesstart 2024-01-30, primary completion 2024-04-15, completion 2024-04-30, first posted 2024-08-07, last updated 2024-08-07
Locations1 site in China

Related Papers Related Patents Related Grants Related Experts
All trials for Autonomic Nervous System Imbalance All trials of working night shift

-Summary

To evaluate changes in heart rate variability (HRV) after the six-minute walk test (6MWT) in nurses following a night shift and explore the impact of night shift work on the regulation of the autonomic nervous system in the heart.

Thirty-five female nurses, with a mean age of 28.7 years (range 21.0-37.0 years), participated in this study. On the first and second mornings after a night shift, the nurses performed the 6MWT. During the test, electrocardiogram (ECG) signals, blood pressure, and walking distance were recorded simultaneously.

Expand all sections  ·  Collapse all

+Arms and interventions

  • working night shift (Behavioral), also known as night shift: working night shift

+Outcome measures

Primary outcomes

  • Delta HRV during the 6MWT [18 minutes]: On the first and second mornings after a night shift, the nurses performed the 6MWT.During the test, electrocardiogram (ECG) signals was recorded simultaneously.

+Eligibility

Sex: Female, ages: 18 Years to 60 Years, accepts healthy volunteers

Inclusion Criteria:

* Female nurses aged ≥ 18 years who had undergone annual physical examinations, did not have serious cardiopulmonary diseases, and were able to walk normally were considered for inclusion in the study.

Exclusion Criteria:

* (ⅰ) having children at home who require night care; (ⅱ) current pregnancy; (ⅲ) engaging in activities that significantly impact heart rate, such as sexual activity, 24 hours before and 24 hours after working night shifts; (ⅳ) history of thyroid dysfunction, hypertension, diabetes, coronary heart disease, etc.; (ⅴ) experiencing upper respiratory tract infection, fever, cough, diarrhea, or other illnesses within 1 week before the planned enrollment; (ⅵ) consuming coffee or strong tea, smoking, drinking alcohol, or using other substances that affect heart rate 3 days before the planned enrollment; (ⅶ) taking β-receptor blockers, sleeping pills, psychotropic drugs, or other medications that affect heart rate; and (ⅷ) judged by the investigator to be unsuitable for participation in this study.

+Locations (1)

FacilityCityCountryStatus
Nanfang Hospital, Southern Medical UniversityGuangzhou, GuangdongChina

+Publications

  • Results publication: Zhan T, Zhang Z, Shi Z, Xie H, Zha D, Wei X. Factors influencing heart rate variability in nurses following night shifts: a prospective observational clinical study. BMC Nurs. 2025 Oct 22;24(1):1318. doi: 10.1186/s12912-025-03975-0. PMID 41126139
  • Results publication: Zhan T, Wei X, Zhang Z, Shi Z, Xie H, Ma X, Pan S, Zha D. The impact of working night shifts on cardiac autonomic nervous regulation during the six-minute walk test in nurses. BMC Nurs. 2024 Dec 18;23(1):907. doi: 10.1186/s12912-024-02563-y. PMID 39696211