Retrospective Analysis of Spray Skin Treats for Severe Burns

NCT06170424 — Completed, 85 participants, First Affiliated Hospital, Sun Yat-Sen University

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A Real-world 10-year Single Center Experience With Spray Skin in the Treatment of Extensive Severe Burns

Registry	NCT06170424
Status	Completed
Study type	Observational
Enrollment	85 (Actual)
Sponsor	First Affiliated Hospital, Sun Yat-Sen University (Other)
Conditions	Morality, Skin Graft Complications
Interventions	spray skin, Control group (Procedure)
Dates	start 2012-01-01, primary completion 2021-12-31, completion 2022-12-31, first posted 2023-12-14, last updated 2023-12-14
Locations	1 site in China

-Summary

This study investigated the efficacy of novel approach spray skin for extensive severe burns treatment.

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+Detailed description

Burns are a global public health problem. This study investigated the efficacy of novel approach spray skin (autologous skin cell suspension combined with split-thickness skin grafting, STSG) for extensive severe burns treatment.

We performed a real-world retrospective analysis of extensive burns patients (> 50% TBSA) from our hospital last 10 years.

+Arms and interventions

Arm	Type	Interventions	Description
experimental gourp		Procedure: spray skin	The patients who used the autologous skin cell suspension combined with skin grafting.
Control group		Procedure: Control group	The patients who used split-thickness skin grafting.

spray skin (Procedure): The patients who used the autologous skin cell suspension combined with skin grafting.
Control group (Procedure): The patients who used skin grafting.

+Outcome measures

Primary outcomes

survival rate [through study completion, an average of 1 year]: Patient survival during hospitalization

Secondary outcomes

complication of skin graft [the take rate in the postoperative day 30, 60, 90]: the survival of grafting skin
length of hospital [through study completion, usually no more than 6 months]: The time during which the patient was hospitalized

+Eligibility

Sex: All, ages: 18 Years to 80 Years

Inclusion Criteria:

* patients with > 50% TBSA

Exclusion Criteria:

* died within 1 week after admission
* admitted to hospital more than 1 week after injury

+Locations (1)

Facility	City	Country	Status
Department of Burn Surgery, The First Affiliated Hospital of Sun Yat-sen University	Guangzhou, Guangdong	China

+Investigators

Jiayuan Zhu, Principal investigator, First Affiliated Hospital, Sun Yat-Sen University