Neural Mobilization With Task Based Activities on Upper Limb in Patients With Chronic Stroke.

NCT06131827 — Not applicable, Unknown, 34 participants, Riphah International University

ClinicalTrials Daily · Areas · Conditions · Drugs · Sponsors ·

Combined Effects of Neural Mobilization With Task Based Activities on Spasticity and Motor Function of Upper Limb in Patients With Chronic Stroke.

Registry	NCT06131827
Status	Unknown
Phase	Not applicable
Study type	Interventional; randomized, parallel, masking: single, treatment
Enrollment	34 (Estimated)
Sponsor	Riphah International University (Other)
Conditions	Chronic Stroke
Interventions	Neural mobilization, Task based activities (Other)
Dates	start 2023-07-17, primary completion 2024-01-15 (estimated), completion 2024-01-22 (estimated), first posted 2023-11-14, last updated 2023-12-29
Locations	1 site in Pakistan

-Summary

Stroke is defined as sudden neurological disruption of blood supply to brain. It is most common disease that causes severe disabilities like hemiparesis which is most common motor impairment that leads to persistent upper limb dysfunction. In this study we use two techniques to improve upper limb motor dysfunction and reduce spasticity. One is task-based activities which is used to improve motor function and focus on active participation rather than normal movement pattern and other is neural mobilization which aims to reduce spasticity which is most common in stroke patients.

Expand all sections · Collapse all

+Detailed description

This study will be randomized controlled trial. Participants having stroke past 6 month to 1 year and mini mental state examination score >21 will be included in this study. And participants with severe orthopedic deformity, joint pain and visual impairment will be excluded from this study. The sample size will consist of 34 participants selected through non probability convenient sampling technique, which will further be randomized through sealed envelope method and will divide into two groups .Data will be collected using assessment tools, including the Fugl Mayer assessment scale, box and block test and wolf motor function test. 17 Participants will be assigned to the interventional group (A )which will undergo neural mobilization of median nerve with task based activities .Neural mobilization technique will be performed with twenty oscillations per minute being repeated three sets of one minute respecting one minute interval for rest between each set for 4 days weekly for 6 week.

while task based activities will be performed with the dosage of 45 minutes session 5 days weekly for 6 weeks and 17 participants will be assigned to control group (B

)which will undergo only neural mobilization of median nerve and will receive neural mobilization with twenty oscillations per minute being repeated three sets of one minute respecting one minute interval for rest between each set for 4 days weekly for 6 weeks. After applying both interventions motor function improvement and spasticity reduction will be measured by using BBT, wolf motor scale and fugl -Meyer assessment scale and data will be analyzed through sPss Version 25.

+Arms and interventions

Arm	Type	Interventions	Description
Neural mobilization	Experimental	Other: Neural mobilization	Neural mobilization technique will be perormed with twenty oscillations per minute being repeated three sets of one minute respecting one minute interval for rest between each set for 4 days weekly for Six week.
Task based activities	Experimental	Other: Task based activities	Task based activities consisted of different type of task which will be performed with the doasage of 45 minutes per session 5 days weekly for 6 weeks.

Neural mobilization (Other), also known as Task based activities: Neural mobilization will be performed with twenty oscillations per minute being repeated three sets of one minute respecting one minute interval of rest between each set for 4 days weekly for six week
Task based activities (Other): Task based activities consisted of different types task which will be performed with the dosage of 45 minute session 5 days weekly for six week.

+Outcome measures

Primary outcomes

Box and block test [6 weeks]: It measures unilateral gross manual dexterity
Wolf motor Function Test [6 weeks]: The Wolf Motor Function Test (WMFT) quantifies upper extremity (UE) motor ability through timed and functional tasks
Fugl -Meyer assessment scale [6 weeks]: It measure motor ability of upper extremity

+Eligibility

Sex: All, ages: 30 Years to 55 Years

Inclusion Criteria:

* Male and female stroke patients.
* 6 month to one year post stroke .
* Age 30-55
* Stable patients
* Mini - mental state examination>2
* Modified ashworth Scale equal<+1

Exclusion Criteria:

* Orthopedic deformity
* Patients undergo bottulinuminjection toxin injection
* Visual impairments
* Joint pain (elbow, shoulder, wrist)

+Locations (1)

Facility	City	Country	Status
Ripha international university	Lahore, Punjab Province	Pakistan	Recruiting

+Investigators

Memona Ayesha, Ms-NMPT, Principal investigator, Ripha international university