Clinic And Biologic Efficiency And Tolerance Of Oral Immunotherapy Protocol In Hazelnut Allergic Children
| Registry | NCT04841850, acronym ENOIME |
|---|---|
| Status | Completed |
| Study type | Observational |
| Enrollment | 70 (Actual) |
| Sponsor | Hospices Civils de Lyon (Other) |
| Conditions | Allergy, Nut, Pediatric ALL |
| Interventions | Clinical and biological characteristics (Other) |
| Dates | start 2021-03-01, primary completion 2021-04-01, completion 2021-05-15, first posted 2021-04-12, last updated 2021-09-17 |
| Locations | 1 site in France |
Related Papers Related Patents Related Grants Related Experts
AI Assistant Save
All trials for Allergy, Nut All trials for Pediatric ALL All trials of Clinical and biological characteristics
Prevalence of food allergy in the world has been inscreasing in recent years. Among nut allergy, hazelnut allergy is the most widespread in Europe and particularly in France. The current treatment for hazelnut allergy is based on eviction and wearing of an emergency kit with adrenaline auto-injector pens, to be used in the event of severe anaphylactic reaction. Oral immunotherapy (OIT) is a treatment that is now increasingly being offered as an alternatice to eviction. There are few published data concerning hazelnut OIT in Europe, where its consumption is nevertheless very high.
The main objective of our study is to evaluate the clinical efficacy of the hazelnut OIT protocol, implemented since 2015 in the pneumology and allergology-paediatric department of the Mother and Child Hospital in Bron, in hazelnut allergic children under 18 years old.
The secondary objectives will be to evaluate the biological efficacy and clinical tolerance of the protocol.
The study is retrospective and observational, and is based on the collection of medical data from patient records.
| Arm | Type | Interventions | Description |
|---|---|---|---|
| Hazelnut allergic children under oral immunotherapy | Other: Clinical and biological characteristics | * Children Under eighteen years of age * Convincing clinical history of hazelnut allergy * Positive hazelnut prick test or specific IgE * Under IOT hazelnut protocol in pneumology and allergology-paediatric departement of the Mother and Child Hospital in Bron |
Sex: All, ages: 1 Year to 18 Years
Inclusion Criteria: * Aged Under eighteen years old * Hazelnut allergy (clinically and biologically) * Under IOT hazelnut protocol in Pneumo/allergology-paediatric departement of the Mother and Child hospital in Bron Exclusion Criteria: * Lack of consent to be included in the study (by their parents) * Age > 18 years old
| Facility | City | Country | Status |
|---|---|---|---|
| Pneumology allergology-paediatric department of the Mother and Child Hospital | Bron | France |