Role of Herbal Dentifrices in the Management of Plaque Induced Gingivitis

NCT04830176 — Not applicable, Completed, 30 participants, Ajman University

ClinicalTrials Daily · Areas · Conditions · Drugs · Sponsors ·

Role of Moringa Dentifirice in the Management of Plaque Induced Gingivitis. A Clinical Crossover Study

Registry	NCT04830176
Status	Completed
Phase	Not applicable
Study type	Interventional; randomized, crossover, masking: double, prevention
Enrollment	30 (Actual)
Sponsor	Ajman University (Other); collaborators: A B Shetty Memorial Institute of Dental Science
Conditions	Gingiva; Infection, Plaque, Dental
Interventions	dentifrice (Other)
Dates	start 2021-01-20, primary completion 2021-03-20, completion 2021-03-28, first posted 2021-04-05, last updated 2021-04-08
Locations	1 site in India

-Summary

The clinical cross over study involves the use of two herbal based dentifirices moringa and miswak and its efficacy in reducing plaque induced gingivitis. The patients selected are provided with details regarding the research format and consent taken.

Expand all sections · Collapse all

+Detailed description

The clinical cross over study involves use of miswak and moringa dentifrices. The patients selected are 30 in no and are selected based on having gingival inflammation due to plaque accumulation. All other cases related to gingival inflammation along with patients with underlying systemic disease are excluded from the study.

At baseline, plaque and gingival scores are recorded, followed by giving one of the dentifrice to the patient for brushing. The patients are asked to brush twice a day and asked to report after 72 hrs, following which another recording of plaque and gingival scores are recorded.

The patients are then asked to use their own tooth paste for a period of 2 weeks as a wash out period and recalled after this 2 week interval.

The patients are then given the second dentifrice and asked to brush for 72 hrs and then asked to report again for a plaque and gingival score evaluation.

+Arms and interventions

Arm	Type	Interventions	Description
moringa	Active comparator	Other: dentifrice	First phase of subjects were given dentifrice for brushing
miswak	Active comparator	Other: dentifrice	second phase of subjects were given dentifrice for brushing

dentifrice (Other): use of dentifrices for brushing

+Outcome measures

Primary outcomes

plaque scores [72 hours]: plaque score recorded using calibrated periodontal probes

Secondary outcomes

Gingival inflammation scores [72 hours]: Gingival bleeding scores recorded using caliberated periodontal probes

+Eligibility

Sex: All, ages: 20 Years to 60 Years, accepts healthy volunteers

Inclusion Criteria:

* subjects having only plaque induced gingival inflammation

Exclusion Criteria:

* Subjects having gingival inflammation related to underling systemic diseases
* Subjects taking medications
* Gingival inflammation related to other causes

+Locations (1)

Facility	City	Country	Status
AB shetty Institute of dental sciences	Mangaluru	India