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MSSA and MRSA Screening in Patients Undergoing Elective TJA: the Benefits of Next-generation Sequencing

NCT04574752 — Unknown, 163 participants, Rothman Institute Orthopaedics

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RegistryNCT04574752
StatusUnknown
Study typeObservational
Enrollment163 (Actual)
SponsorRothman Institute Orthopaedics (Other)
ConditionsStaphylococcus Aureus, Next Generation Sequencing, Total Joint Arthroplasty
Interventionsnext generation sequencing (Diagnostic test)
Datesstart 2020-08-30, primary completion 2021-08-30 (estimated), completion 2021-08-30 (estimated), first posted 2020-10-05, last updated 2020-10-05
Locations1 site in United States

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-Summary

The aims of this study were to evaluate the diagnostic performance of molecular and culture techniques in S. aureus screening using paired nasal and groin swabs, to determine, if any, discrepancy between the diagnostic techniques and to model the potential effect of different diagnostic techniques on S. aureus detection in orthopaedic patients

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+Arms and interventions

  • next generation sequencing (Diagnostic test): diagnostic performance of molecular and culture techniques in S. aureus screening using paired nasal and groin swabs, to determine, if any, discrepancy between the diagnostic techniques on S. aureus detection in orthopaedic patients

+Outcome measures

Primary outcomes

  • Diagnostic techniques to identify S. aureus in total joint replacement patients [1 day]: to model the potential effect of different diagnostic techniques on S. aureus detection in orthopaedic patients.

+Eligibility

Sex: All, ages: 18 Years to 80 Years, accepts healthy volunteers

Inclusion Criteria:

* All patients undergoing primary total knee or total hip arthroplasty at our institution will be eligible.

Exclusion Criteria:

* Patients included in other prospective studies

+Locations (1)

FacilityCityCountryStatus
Rothman Orthopaedic InstitutePhiladelphia, PennsylvaniaUnited States

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