Buccal Mucosal Graft for the Repair of Iatrogenic Pelviureteric Junction Obstruction or Ureteric Stricture.

NCT04503330 — Not applicable, Unknown, 20 participants, Cairo University

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Using Buccal Mucosal Graft as an Augmention Graft for Complex Cases of Iatrogenic Pelviureteric Junction Obstruction and Long Segment Ureteric Stricture Disease.

Registry	NCT04503330
Status	Unknown
Phase	Not applicable
Study type	Interventional; na, single group, masking: none, treatment
Enrollment	20 (Estimated)
Sponsor	Cairo University (Other)
Conditions	Pelvi Ureteric Junction Obstruction or Ureteral Stricture
Interventions	buccal mucosal graft to repair iatrogenic PUJO (Procedure)
Dates	start 2020-10-01 (estimated), primary completion 2021-11-01 (estimated), completion 2021-12-01 (estimated), first posted 2020-08-07, last updated 2020-08-07

-Summary

Prospective study to evaluate the safety and efficacy of using buccal mucosal graft for repairing complex cases of iatrogenic pelvi ureteric junction obstruction and long segment ureteric stricture disease.

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+Detailed description

A graft of buccal mucosa will be used to augment either the narrow unhealthy pelviureteric junction or a narrow long segment of the ureter.

after freeing the narrowed part, a posterior incision will be made in the ureter or renal pelvis then the graft will be implanted on the psoas muscle using interrupted sutures in a position the allows easy anastomosis to the ureter or renal pelvis.

Alternatively a lateral incision in the renal pelvis or the ureter may be done for the graft anastomosis and then surrounded with omenal flap to ensure a good blood supply for the graft.

+Arms and interventions

Arm	Type	Interventions	Description
Patients with iatrogenic PUJO	Experimental	Procedure: buccal mucosal graft to repair iatrogenic PUJO	patients with iatrogenic PUJO or long segment ureteric stricture disease for safety and efficacy of using buccal graft for repair

buccal mucosal graft to repair iatrogenic PUJO (Procedure): Augmented buccal mucosal graft anastomosis to repair iatrogenic PUJO or long segment ureteric stricture disease

+Outcome measures

Primary outcomes

Number of Participants with patent renal pelvis and ureter after surgery. [3 months]: 3 months after surgery Diuretic renography will be done to judge patency of the pelvis and ureter and resolution of hydronephrosis

+Eligibility

Sex: All, ages: any to 60 Years

Inclusion Criteria:

\- any patient with iatrogenic pelviureteric junction obstruction or long segment ureteric stricture

Exclusion Criteria:

* elderly patients unfit for general anaesthesia.

My Notes

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