Effects of Exercise Training on Fatigue in Thyroid Cancer Survivors

NCT04224792 — Not applicable, Withdrawn, Mayo Clinic

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Registry	NCT04224792
Status	Withdrawn - Due to pandemic, unable to see patients
Phase	Not applicable
Study type	Interventional; non randomized, parallel, masking: none, supportive care
Sponsor	Mayo Clinic (Other)
Conditions	Thyroid Cancer
Interventions	Center-based exercise program, Home-based exercise program (Other)
Dates	start 2022-09-30 (estimated), primary completion 2024-09-30 (estimated), completion 2024-12-30 (estimated), first posted 2020-01-13, last updated 2022-06-09

-Summary

Researchers are trying to determine whether an exercise program reduces fatigue and improves physical activity in thyroid cancer patients.

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+Arms and interventions

Arm	Type	Interventions	Description
Center-based exercise group	Experimental	Other: Center-based exercise program	Subjects will be enrolled into a center-based exercise program.
Home-based exercise group	Experimental	Other: Home-based exercise program	Subjects will be enrolled into a home-based exercise program.

Center-based exercise program (Other): A routine individualized exercise prescription and supervised exercise sessions at a minimum of once per week for 11 weeks with an exercise prescription updated monthly.
Home-based exercise program (Other): A one-time supervised exercise session with Cardiac Rehabilitation staff and a routine individualized exercise prescription for exercises to do at home. Additionally, weekly telephone followup calls by a clinical exercise physiologist for 11 weeks consisting of an exercise tip.

+Outcome measures

Primary outcomes

Fatigue symptoms [Baseline, 12 weeks]: Change in fatigue symptoms measured using the self-reported Fatigue Symptom Inventory (FSI) survey
Physical activity [Baseline, 12 weeks]: Change in physical activity measured using the self-reported International Physical Activity questionnaire

+Eligibility

Sex: All, ages: 18 Years to any

Inclusion Criteria:

* Adults ≥18yrs of age with well-differentiated thyroid cancer and self-reported fatigue any time after initial treatment of thyroid cancer.
* English speaking
* Able to provide consent

Exclusion Criteria:

* Pregnant
* Medullary thyroid cancer
* Anaplastic thyroid cancer
* Physical limitations to perform exercise

+Investigators

Regina Castro, MD, Principal investigator, Mayo Clinic