IOP Reduction and Complications of Polymethyl Methacrylate GDD on Glaucoma Patient

The study is to measure the efficacy of new GDD that made with polymethyl methacrylate. The primary outcome is IOP reduction. The secondary outcome is glaucoma medication post surgery and complication that occurred during the follow up. The subjects are refractory glaucoma patients that need glaucoma drainage device implantation. The measurement are collected on first day, first month, third month, sixth month and twelve month. The IOP will be measured using GAT (Goldmann applanation tonometer), but if the subjects are not cooperative, they will be measured using i-care. On the follow up, the glaucoma medication needed will be noted and also for the complication and the need for other surgery, e.g. AC formation using viscoelastic, repair tube/plate exposure, cyclo photocoagulation, etc.

• Glaucoma Implant (Procedure)

Primary outcomes

• IOP reduction of Polymethylmethacrylate Glaucoma Drainage Device in refractory Glaucoma Patients [pre implantation surgery, day 1, 7, 30, 60, 90 post implantation surgery]: Intraocular pressure (IOP)

Secondary outcomes

• The glaucoma medication that was used pre and post operative [pre implantation surgery, day 1, 7, 30, 60, 90 post implantation surgery]: The glaucoma medication used pre and post op
• The complications that occurred during the follow up [during the surgery, day 1, 7, 30, 60, 90 post implantation surgery]: The complications that occurred during the follow up

Sex: All, ages: 18 Years to any

Inclusion Criteria:

* End stage glaucoma patients whose IOP is failed to be controlled by glaucoma medications
* Patients that are willing to participate in the study
* Patients with <6/60 visual acuity
* Patients above 18 years

Exclusion Criteria:

* Patients with combination surgery indication (eg. glaucoma with cataracts)
* Eyes with congenital disease of anterior segment dysgenesis
* Eyes with uneven surface of the cornea that the measurement IOP with Goldmann tonometer could be difficult
* Eyes with broad conjungtival cicatrix that are impossible to be implanted

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• Virna Dwi Oktariana Asrory, PhD, Principal investigator, Universitas Indonesia