Mayo Clinic IBD Biobank

Subjects will be sent a letter detailing the proposed biobank and soliciting enrollment. Following the informed consent process, subjects will provide a blood sample (50 ml), urine sample (50 ml), and stool. The blood and urine samples will either be collected at the one of the Mayo Clinic outpatient laboratories or by a mail-out kit. Subjects will be asked to complete a questionnaire and 24-hour food recall questionnaire (completed online).

• Blood Draw (Procedure): 50 ml will be collected
• Urine Collection (Procedure): 50 ml will be collected
• Stool Collection (Procedure): Three 25 ml tubes will be collected

Primary outcomes

• Study Participants [50 years]: Total number of participants in the study

Secondary outcomes

• Urine Collection [50 years]: Total number of urine samples collected
• Blood Collection [50 years]: Total number of blood samples collected
• Stool Collection [50 years]: Total number of stool samples collected

Sex: All, ages: 18 Years to 85 Years, accepts healthy volunteers

Inclusion Criteria:

* Patients diagnosed with inflammatory bowel disease (IBD) who are between the ages of 18 and 85 at time of study enrollment.
* The diagnosis of IBD will be based on the standard IBD criteria including biochemical and colonoscopy screening.
* Women with inflammatory bowel disease of childbearing potential and pregnant women will be offered enrollment because there is no risk to an unborn child in this investigation.
* Patients between the ages of 18 and 85 without history of IBD or colon cancer.

Exclusion Criteria:

* Patients with known liver disease.
* Patients unable to provide informed consent.
* Prisoners and institutionalized individuals.
* Patients with a history of colorectal cancer.

• Konstantinos N. Lazaridis, MD, Principal investigator, Mayo Clinic