Biometric Indicators of Eyes With Occult Lens Subluxation
| Registry | NCT03752710 |
|---|---|
| Status | Completed |
| Study type | Observational |
| Enrollment | 183 (Actual) |
| Sponsor | Tianjin Medical University Eye Hospital (Other) |
| Conditions | Subluxation of Lens |
| Dates | start 2016-01-01, primary completion 2017-12-01, completion 2017-12-01, first posted 2018-11-26, last updated 2018-11-27 |
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All trials for Subluxation of Lens
In this work, we evaluated the biometry data of lens subluxation inducing acute angle closure which were misdiagnosed as primary angle closure at the first visit, and compared with the data of chronic angle closure glaucoma, cataract, primary acute angle closure.
| Arm | Type | Interventions | Description |
|---|---|---|---|
| Acute primary angle closure | |||
| Acute secondary angle closure induced by LS | |||
| Cataract | |||
| Primary chronic angle closed glaucoma |
Sex: All
ASAC-LS was diagnosed according to the following criteria, including sudden pain in the eye, decreased vision with or without nausea and vomiting. Slit lamp microscopy reveals phacodonesis, lens inclination or vitreous herniation into the anterior chamber, central and peripheral shallow anterior chamber, and asymmetric iris bulge. All patients were confirmed during the surgery to have LS. APACG was diagnosed with the following criteria6, 7 8, including substantially elevated IOP and closed angle, acute eye pain, blurred vision, or nausea and vomiting. More importantly, ischemic injury caused by acute ocular hypertension, ciliary or mixed congestion, corneal edema, and glaucoma flecks should be detected. The diagnostic criteria of CPACG included narrow angle with anterior synechiae of varying widths, IOP > 22 mmHg, and glaucomatous optic disc damage and visual field shrinkage9-11 The angle closure should be more than two quadrants, yet there was no ischemic injury in the anterior segment caused by acute ocular hypertension. Exclusion criteria were history of laser peripheral iridotomy or peripheral iridectomy, glaucoma filtration surgery, angle closure caused by ocular trauma, uveitis, neovascularization or lens swelling or hyper mature lens. The patients with acute angle closure in both eyes were excluded. The subjects in which Lenstar LS900 examination could not be performed because of severe lens opacity or corneal edema were also not included in the study.