Evaluation of The Accuracy of CAD-CAM Custom Made Titanium Miniplates In Positioning of the Genial Segment in Computer Guided Genioplasty

• Osseous Genioplasty (Procedure): Surgical Procedure that cuts the chin and reposition it in the correct place

Primary outcomes

• Accuracy Of the Custom Made Miniplate [one year]: Hausdorff function analysis (Topographic Color Mapping) by superimposition of both preoperative and postoperative computed tomography 3D scans and obtaining numerical values. Data management and analysis will be performed using Statistical Package for Social Sciences (SPSS) vs.21. Numerical data will be summarized using means and standard deviations or median and range as appropriate. Correlation analysis between Accuracy of computer assisted custom made plate and preoperative 3D virtual planning will be done using Pearson or Sperman rho as appropriate. Paired t test will be done and equivelance limit will be tested. All p- values are two sided. P- Values <0.05 will be considered significant.

Secondary outcomes

• Patient Satisfaction (Esthetics) [one year]: Questionnaire with numerical scale ranging from minimal score ( number 1) to maximum score (number 10) in ascending manner where the minimal score indicated unpleasant or unsatisfactory result ( doesn't meet the patient expectation) and maximum score indicated satisfactory and pleasant result (fully meets patient satisfaction).

Sex: All, ages: 18 Years to 60 Years, accepts healthy volunteers

Inclusion Criteria:

* Patients with genial deformeties that require surgical correction.
* Patients with chin asymmetry.
* Patients older than 18 years old.

Exclusion Criteria:

* Patients with uncontrolled systemic disease (Diabetes Mellitus).
* Previous Radiotherapy to the area of interest.
* Patients on bisphosphonates therapy.
* Patients underwent previous or concomitant mandibular orthognathic surgery.

• Nader Na Elbokle, Phd Holder, Study director, Cairo University