Clinical Evaluation of Some Local Antimicrobial Agents' Adjunctive Effects On Periodontal Parameters and Halitosis With Subgingival Ultrasonic Instrumentation in Periodontitis Patients: A Randomized Clinical Study
| Registry | NCT03468595 |
|---|---|
| Status | Completed |
| Phase | Not applicable |
| Study type | Interventional; randomized, parallel, masking: single, supportive care |
| Enrollment | 90 (Actual) |
| Sponsor | Near East University, Turkey (Other) |
| Conditions | Halitosis |
| Interventions | ultrasonic (Piezon Master 700) performed with Listerine, ultrasonic (Piezon Master 700) performed with CHX, ultrasonic (Piezon Master 700) performed with serum (Device) |
| Dates | start 2016-03-01, primary completion 2016-09-01, completion 2017-05-01, first posted 2018-03-16, last updated 2018-03-16 |
Related Papers Related Patents Related Grants Related Experts
All trials for Halitosis All trials of ultrasonic (Piezon Master 700) performed with Listerine All trials of ultrasonic (Piezon Master 700) performed with CHX
The aim of this trial was to establish the clinical efficacy of Listerine and chlorhexidine (CHX) when used as a cooling agent with ultrasonic instrumentation, on periodontal parameters and halitosis.
Ninety patients with periodontal disease participated for the study. Individuals were randomly selected to a control and test groups. At baseline, all subjects completed a questionnaire and carried out an examination. Standard periodontal outcome variables were assessed. For both groups, the plaque index (PI), gingival index (GI), pocket depth (PD), bleeding on probing (BOP) and clinical attachment level (CAL) scores were enrolled at baseline and after 30 days. Volatile sulphur compound (VSC) levels were evaluated by a Halimeter (Interscan Corp., Chatsworth, CA, USA) at baseline (T0), immediately after treatment (T1), and at 7 (T2), 14 (T3) and 30 days (T4).
| Arm | Type | Interventions | Description |
|---|---|---|---|
| test 1 | Experimental | Device: ultrasonic (Piezon Master 700) performed with CHX | The treatment of periodontitis was performed with ultrasonic instrumentation (Piezonmaster 700; Electro Medical Systems, Nyon, Switzerland) with CHX (Drogsan, Istanbul, Turkey, 0.2%) was performed at one session for once. |
| test 2 | Experimental | Device: ultrasonic (Piezon Master 700) performed with Listerine | The treatment of periodontitis was performed with ultrasonic instrumentation (Piezonmaster 700; Electro Medical Systems, Nyon, Switzerland) with Listerine (Johnson \& Johnson, Istanbul, Turkey, containing, 21.6% ethanol, 0.092% eucalyptol, 0.064% thymol, 0.042% menthol and 0.06% methyl salicylate) was performed at one session for once. |
| control | Active comparator | Device: ultrasonic (Piezon Master 700) performed with serum | The treatment of periodontitis was performed with ultrasonic instrumentation (Piezonmaster 700; Electro Medical Systems, Nyon, Switzerland) with distilled water was performed at one session for once. |
Sex: All, ages: 20 Years to 80 Years, accepts healthy volunteers
Inclusion Criteria: * In the present trial, who had periodontitis from patients undergoing periodontal treatment at the Department of Periodontology of our institution Exclusion Criteria: * Individuals who presented any systemic disorders which cause halitosis (diabetes mellitus, nephropathy, liver disease, gastrointestinal diseases, respiratory problems), pregnancy or lactation, individuals who had taken antibiotics over the last 6 months or permanently used any drugs, individuals who had any form of periodontal treatment within 6 months prior to the study.