TrialReader


Conjoined Twins: a Report of Four Cases.

NCT03388684 — Completed, 4 participants, Assiut University

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  
RegistryNCT03388684, acronym CT
StatusCompleted
Study typeObservational
Enrollment4 (Actual)
SponsorAssiut University (Other)
ConditionsConjoined Twin
InterventionsConjoined twin separation surgery (Procedure)
Datesstart 2000-02-01, primary completion 2017-10-01, completion 2017-10-01, first posted 2018-01-03, last updated 2024-06-25

Related Papers Related Patents Related Grants Related Experts
AI Assistant Save
All trials for Conjoined Twin All trials of Conjoined twin separation surgery

-Summary

The present study aims to report our experience in conjoined twin separation surgery in Assuit university and pediatric hospital, Assiut university, Assiut, Egypt over a period of 20 years.

Expand all sections  ·  Collapse all

+Detailed description

A conjoined twin is a subset of monozygotic twin gestation. It's a rare phenomenon with an incidence of 1 in 50,000 to 1:100,000 births with the higher incidence in Africa and Southwest Asia. Based on the terminology proposed by Spencer and colleagues, conjoined twins are classified according to the most prominent site of conjunction into three major groups; First, twins with a ventral union; \[cephalopagus (head), thoracopagus (Thorax), omphalopagus (Abdomen) and ischiopagus (pelvis)\]. Second; twins with a dorsal union; \[pygopagus (sacrum), rachipagus (spine, back) and craniopagus (cranium)\] and lastly; twins with a lateral union that is referred to as parapagus (side). Depending on the aspect of the embryonic disc, the most common types are thoracopagus (19%).

Surgical separation of conjoined twins is extremely challenging taking in consideration the high perioperative risk. The low incidence of such surgeries and anatomical variations in each type of conjoined twins makes each separation surgery a unique experience.

+Arms and interventions

  • Conjoined twin separation surgery (Procedure), also known as CT Separation: This study included 4 case reports on conjoined twins (CT), 2 male and three female patients; 3 of them were parasitic and one was conjoined. We operated upon 2 parasitic and one conjoined. The 1st case died preoperatively.

+Outcome measures

Primary outcomes

  • Success of the conjoined twin separation surgery [For each case was the 1 week survival]: The operative details of the separation surgery were written in details and the separation process was showen in pictures.

+Eligibility

Sex: All, ages: 1 Day to 30 Days

Inclusion Criteria:

* conjoined twins
* symmetrical or
* asymmetrical.

Exclusion Criteria:

* conjoined twins incompatible with life
* conjoined twins with decapitating medical illness.

+Publications

  • Results publication: Takrouney MH, Ibrahim IA, Abdel-Ghaffar HS, Abdel-Wahhab AI, Mostafa MM, Ali WN, Abd-Elaal MS. Conjoined twins: A report of four cases. Int J Surg Case Rep. 2020;73:289-293. doi: 10.1016/j.ijscr.2020.06.072. Epub 2020 Jun 20. PMID 32721891

+Investigators

  • Hala S Abdelghaffar, MD, Principal investigator, Professor in anesthesia and intensive care department, faculty of medicine, Assiut university, Egypt.

My Notes