TrialReader


The Endothelial Count in Pxf

NCT03265457 — Unknown, 20 participants, Assiut University

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  

The Corneal Endothelial Cell Count in Eyes With Pseudoexfoliation Syndrome

RegistryNCT03265457
StatusUnknown
Study typeObservational
Enrollment20 (Estimated)
SponsorAssiut University (Other)
ConditionsPseudoexfoliation Syndrome
InterventionsSpecular microscopy (Other)
Datesstart 2018-10-01 (estimated), primary completion 2019-10-01 (estimated), completion 2020-10-01 (estimated), first posted 2017-08-29, last updated 2018-06-26

Related Papers Related Patents Related Grants Related Experts
AI Assistant Save
All trials for Pseudoexfoliation Syndrome All trials of Specular microscopy

-Summary

Pseudoexfoliation Syndrome Is a common disorder in Egypt. IT is one of the common causes of coexisting cataract and glaucoma. It may be associated with a less than normal endothelial count.

Expand all sections  ·  Collapse all

+Detailed description

The corneal Endothelium is essential for the maintenance of normal corneal hydration, thickness, and transparency.

In patients with pseudoexfoliation syndrome , quantitative and qualitative morphological changes of the corneal endothelium have been demonstrated in specular and electron microscopic studies.

Specular microscopy is a non-invasive technique to access the structure and function of the corneal endothelium.

Our research question is to study Endothelial cell count in patients with pseudoexfoliation syndrome \& compare it to age matched group.

+Arms and interventions

ArmTypeInterventionsDescription
patient with pseudoexfoliation syndromeOther: Specular microscopyThe corneal Endothelial cell count will be measured by specular microscopy
Normal people at same ageOther: Specular microscopy
  • Specular microscopy (Other): Comparison between corneal Endothelial count in patients with pseudoexfoliation syndrome and age matched group

+Outcome measures

Primary outcomes

  • Comparison between endothelial cell count in patients with Pseudoexfoliation syndrome and age matched controls. [One year]: The corneal Endothelial cell count in patients with pseudoexfoliation syndrome will be measured by the specular microscopy \& compared with the normal endothelial count in people at the same group

+Eligibility

Sex: All, accepts healthy volunteers

Inclusion Criteria:

* Patients with pseudoexfoliation syndrome

Exclusion Criteria:

* Patients with previous intra ocular surgeries.
* Patients with uveitis
* Patients with fuck's endothelial dystrophy

+Publications

  • Miyake K, Matsuda M, Inaba M. Corneal endothelial changes in pseudoexfoliation syndrome. Am J Ophthalmol. 1989 Jul 15;108(1):49-52. doi: 10.1016/s0002-9394(14)73259-3. PMID 2750833

My Notes