The Effect of Concentrated Growth Factors in Regenerative Therapy in Furcation Involvements in Humans
| Registry | NCT03180658 |
|---|---|
| Status | Unknown |
| Phase | Not applicable |
| Study type | Interventional; randomized, parallel, masking: double, treatment |
| Enrollment | 30 (Estimated) |
| Sponsor | Jing Qiao (Other) |
| Conditions | Concentrated Growth Factors, Periodontal Regeneration, Furcation Defects |
| Interventions | GTR + CGF + bone graft, CGF + bone graft (Procedure) |
| Dates | start 2017-05-01, primary completion 2020-05-01 (estimated), completion 2020-07-01 (estimated), first posted 2017-06-08, last updated 2017-06-08 |
| Locations | 1 site in China |
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Objective: To compare the effect of guided tissue regeneration (GTR) + concentrated growth factors (CGF) + bone graft and CGF + bone graft in the treat of II° furcations of human mandibular molars. Methods: At least thirty II°furcation involvements in mandibular molars will be included and randomly divided into two groups. The experimental group will accept GTR + CGF + bone graft therapy, and the control group will accept CGF + bone graft therapy. The clinical examination and cone beam computed tomography (CBCT) will be performed at baseline and 1 year post-surgery.
| Arm | Type | Interventions | Description |
|---|---|---|---|
| experimental | Experimental | Procedure: GTR + CGF + bone graft | GTR+CGF+bone graft, CGF |
| controlled | Active comparator | Procedure: CGF + bone graft | CGF+bone graft |
Sex: All, ages: 18 Years to 70 Years, accepts healthy volunteers
Inclusion Criteria: * II° furcation involvements in mandibular molars * after periodontal therapy. Exclusion Criteria: * not healthy
| Facility | City | Country | Status |
|---|---|---|---|
| Peking university School and Hospital of Stomatology | Beijing, Beijing Municipality | China | Recruiting |