| Registry | NCT02830854 |
|---|---|
| Status | Completed |
| Phase | Phase 3 |
| Study type | Interventional; na, single group, masking: none, supportive care |
| Enrollment | 13 (Actual) |
| Sponsor | University of Novi Sad, Faculty of Sport and Physical Education (Other) |
| Conditions | Cognitive Impairments, Aging |
| Interventions | Molecular Hydrogen (Other) |
| Dates | start 2016-07-01, primary completion 2016-09-01, completion 2016-09-01, first posted 2016-07-13, last updated 2016-10-28 |
| Locations | 1 site in Serbia |
Related Papers Related Patents Related Grants Related Experts
All trials for Cognitive Impairments All trials for Aging All trials of Molecular Hydrogen
A variety of non-pharmacological interventions have been used in the management of Alzheimer's disease (AD) and similar cognitive disorders in elderly, yet no therapeutic modality has demonstrated conclusive positive results in terms of effectiveness. Although it is still unknown what triggers AD, recent studies have shown that AD is associated with brain energy depletion, oxidative stress, and mitochondrial dysfunction. Since supplemental molecular hydrogen (H2) supports cell energy production and acts as a highly bioavailable mitochondria-related antioxidant, it may provide an ideal agent to facilitate treatment and perhaps prevention of AD and similar cognitive disorders in elderly. The overall hypothesis to be evaluated in this project is that administration of H2 will positively affect patient-reported outcomes and clinical biomarkers in men and women suffering from AD.
| Arm | Type | Interventions | Description |
|---|---|---|---|
| Molecular Hydrogen | Experimental | Other: Molecular Hydrogen | Molecular hydrogen: 20 min per day of 3% H2 during 4 weeks |
Sex: All, ages: 65 Years to any, accepts healthy volunteers
Inclusion Criteria: * Age over 65 * No psychiatric comorbidities Exclusion Criteria: * Use of dietary supplements 4 weeks before study commence
| Facility | City | Country | Status |
|---|---|---|---|
| Applied Bioenergetics Lab at Faculty of Sport and PE | Novi Sad, Vojvodina | Serbia |