Pulmonary Hypertension in Patients With Myeloproliferative Neoplasms

NCT02580903 — Completed, 180 participants, Odense University Hospital

ClinicalTrials Daily · Areas · Conditions · Drugs · Sponsors ·

Pulmonary Hypertension in Patients With Philadelphia Chromosome Negative Myeloproliferative Neoplasms; an Observational Prospective Study

Registry	NCT02580903, acronym MPNPH
Status	Completed
Study type	Observational
Enrollment	180 (Actual)
Sponsor	Odense University Hospital (Other)
Conditions	Myeloproliferative Disorders, Pulmonary Hypertension
Interventions	Radiology (Radiation)
Dates	start 2015-02-01, primary completion 2018-02-01, completion 2020-02-01, first posted 2015-10-20, last updated 2020-09-16
Locations	1 site in Denmark

-Summary

This is an observational prospective study aiming to clarify the prevalence of pulmonary hypertension in patients with Myeloproliferative Neoplasms and their prognosis.

All patients attending our department with the above mentioned neoplasms will be offered inclusion in this study. All will have an echo performed and patients identified as being at risk of pulmonary hypertension will be offered complete investigation as specified by the European Cardiology Association.

All patients will be followed up for a total of five years to identify prognosis.

Expand all sections · Collapse all

+Arms and interventions

Radiology (Radiation): Only a small subsample will require CT and right heart catherisation

+Outcome measures

Primary outcomes

Prevalence of pulmonary hypertension at initial presentation and first echo [Initial recruitment]

Secondary outcomes

Mortality [1 and 5 years]
Incidence of pulmonary hypertension while under follow-up [5 years]

+Eligibility

Sex: All, ages: 18 Years to any

Inclusion Criteria:

* Myeloproliferative Neoplasms (PV, ET, PMF according to WHO classification)

Exclusion Criteria:

* Pregnancy
* Lack of informed consent
* Age < 18 years
* Cognitive dysfunctions

+Locations (1)

Facility	City	Country	Status
Odense University Hospital	Odense	Denmark

+Investigators

Mette Brabrand, MD, Principal investigator, Odense University Hospital

My Notes

Public

To Read Reading Read