Preoperative Prevalence of Ulnar Neuropathy and Changes in Ulnar Nerve Latency During Surgery

NCT02533024 — Not applicable, Completed, 4 participants, University of Toledo Health Science Campus

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Registry	NCT02533024
Status	Completed
Phase	Not applicable
Study type	Interventional; na, single group, masking: none, diagnostic
Enrollment	4 (Actual)
Sponsor	University of Toledo Health Science Campus (Other)
Conditions	Ulnar Neuropathy
Interventions	Electromyography (Other)
Dates	start 2015-08-01, primary completion 2017-04-28, completion 2017-04-28, first posted 2015-08-26, last updated 2017-09-25
Locations	1 site in United States

-Summary

This study is to investigate the incidence of undiagnosed ulnar neuropathy in patients undergoing surgery. The investigators hope to determine if patients with ulnar neuropathy have changes in nerve conduction latency during surgery.

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+Detailed description

After obtaining an informed consent, the participating subjects will be asked a few questions relating to ulnar nerve dysfunction. Following this the investigators will do a focused physical exam looking for decrement of sensation in the distribution of the ulnar nerve and muscle strength of the hand muscles supplied by the ulnar nerve. After this the subjects will undergo an EMG exam to measure the conduction velocity of the ulnar nerve. Basically the nerve will be stimulated with a small current and the resultant muscle activity of the hand muscle will be picked up using an EKG like patch applied to the skin over the hand. If a subject is diagnosed to have ulnar neuropathy preoperatively the investigators would study the EMG based nerve conduction during surgery at 30-60 minute intervals for the duration of surgery. For purposes of comparison the investigators would measure the ulnar nerve conduction during surgery in age and sex matched controls.

+Arms and interventions

Arm	Type	Interventions	Description
Group Cohort	Experimental	Other: Electromyography	All subjects will have nerve conduction studies (Electromyography/EMG) pre-operatively, monitored intra-operatively and immediately post-operative.

Electromyography (Other), also known as EMG: All subjects will have an EMG before, during and immediately after surgery.

+Outcome measures

Primary outcomes

Prevalence of ulnar neuropathy in patients scheduled to undergo anesthesia and surgery as measured by electromyography [Day 1]: Prevalence of undiagnosed or subclinical ulnar neuropathy as determined by electromyography

Secondary outcomes

Amplitude (mV) [Day 1]: Compare preoperative, perioperative and postoperative amplitude changes from EMG
Latency (ms) [Day 1]: Compare preoperative, perioperative and postoperative latency changes from EMG
Velocity (m/s) [Day 1]: Compare preoperative, perioperative and postoperative velocity changes from EMG

+Eligibility

Sex: All, ages: 50 Years to any

Inclusion Criteria:

* 50 yrs of age or older
* Scheduled to undergo a surgical procedure at UTMC with an anticipated length of 2hours or greater

Exclusion Criteria:

* Less than 50yrs
* Not scheduled for a surgical procedure at UTMC or scheduled for a surgical procedure with an anticipated length of less than 2hours

+Locations (1)

Facility	City	Country	Status
University of Toledo	Toledo, Ohio	United States

+Investigators

Andrew B Casabianca, MD, Principal investigator, University of Toledo