The Relationship of Adiponectin in Adipose Tissue, Thy-1 in Plaques, and Inflammatory Mediators With Cardiac Diseases

In addition, we'd like to investigate the association of the investigators' findings with clinical atherosclerotic risks, medications (statins or antiplatelet), and blood sugar. Now, we've established cell assay and successfully transformed mature adipocyte from 3T3-L1 cells. Besides, there were nighty-six patients enrolled into this study. Flow cytometry of Thy-1 and MCP-1 concentration in cultured medium by ELISA were also analyzed.

• CAD (Procedure), also known as coronary artery disease: Patients with CAD diseases proposed to have cardiac operations will be enrolled in this study, but those with congestive heart failure are excluded. Besides, those patients with valve diseases should have patent coronary arteries on coronary angiography.
• VHD (Procedure), also known as valve diseases: Patients with valve diseases proposed to have cardiac operations will be enrolled in this study, but those with congestive heart failure are excluded. Besides, those patients with valve diseases should have patent coronary arteries on coronary angiography.

Primary outcomes

• CD91 (Thy-1) [up to 24 months]

Secondary outcomes

• CD45 [up to 24 months]

Sex: All

Inclusion Criteria:

* coronary artery bypass grafting surgery
* valvular surgery

Exclusion Criteria:

* liver disease (GPT 2 times greater than normal limits)
* chronic renal insufficiency (Creatinine > 2.0 mg/dL)
* neoplastic diseases
* taking steroids
* congestive heart failure

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