The Glycemic and Insulinemic Responses Elicited by Meals Containing Whole Grain Rye Bread or White Wheat Bread

NCT02400411 — Not applicable, Unknown, 15 participants, University of Helsinki

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The Effects of Margarine and Ham or Vegetable Soup on the on the Glycemic and Insulinemic Responses Elicited by Whole Grain Rye Bread or White Wheat Bread

Registry	NCT02400411
Status	Unknown
Phase	Not applicable
Study type	Interventional; randomized, crossover, masking: single
Enrollment	15 (Estimated)
Sponsor	University of Helsinki (Other); collaborators: Fazer Group
Conditions	Blood Glucose Concentration
Interventions	Wheat bread, margarine, ham, soup, rye bread (Other)
Dates	start 2015-03-01, primary completion 2015-10-01 (estimated), first posted 2015-03-27, last updated 2015-09-04

-Summary

This is a postprandial study with healthy volunteers. The glycemic and insulinemic responses elicited by meals containing either whole grain rye bread or white wheat bread as such or combined with margarine and ham and vegetable soup are compared. Blood glucose concentrations are monitored from finger prick blood samples collected before the meal and at 15, 30, 45, 60, 90 and 120 min. Venous samples for insulin concentrations are taken at time-points 0, 30 and 60 min.

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+Arms and interventions

Arm	Type	Interventions	Description
Wheat bread	Experimental	Other: Wheat bread	Bread-based meal
Wheat bread with margarine and ham	Experimental	Other: Wheat bread; Other: margarine; Other: ham	Bread-based meal
Wheat bread with margarine, ham and soup	Experimental	Other: Wheat bread; Other: margarine; Other: ham; Other: soup	Bread-based meal
Rye bread	Experimental	Other: rye bread	Bread-based meal
Rye bread with margarine and ham	Experimental	Other: margarine; Other: ham; Other: rye bread	Bread-based meal
Rye bread with margarine, ham and soup	Experimental	Other: margarine; Other: ham; Other: soup; Other: rye bread	Bread-based meal

Wheat bread (Other)
margarine (Other)
ham (Other)
soup (Other)
rye bread (Other)

+Outcome measures

Primary outcomes

Blood glucose concentration [120 min]

Secondary outcomes

Serum insulin concentration [60 min]

+Eligibility

Sex: Female, ages: 18 Years to 35 Years, accepts healthy volunteers

Inclusion Criteria:

* female
* BMI 18-27 kg/m2

Exclusion Criteria:

* pregnant or breastfeeding
* diabetes, gastrointestinal disease
* regular use of medication
* strict vegetarian or vegan diet
* food allergy
* recent blood donation