Powered Echelon Device in VATS Surgery

The European prospective observational multi-center cohort study aims to collect real-world outcomes of consecutive patients scheduled for VATS lobectomy for histologically confirmed Non-Small Cell Lung Cancer (NSCLC) or scheduled for VATS wedge resection for undiagnosed pulmonary nodule or metastasis from colorectal cancer (CRC) in accordance with their institution's Standard-of-care (SOC).

• VATS for confirmed non-small cell lung cancer (NSCLC) (Procedure), also known as Video-Assisted Thoracoscopic Surgery: Video-Assisted Thoracoscopic Surgery for NSCLC patients

Primary outcomes

• occurrence and duration of post-operative air leak [prolonged air leak defined as longer than 5 days post-op]: occurrence and duration of prolonged air leak defined as longer than 5 days

Secondary outcomes

• volume of estimated intra-operative blood loss [blood loss intra-op and up to 5 days post-op]: volume of estimated intra-operative blood loss

Sex: All, ages: 18 Years to any

Inclusion Criteria:

* Histologically confirmed NSCLC (up to and including Stage II) for patients undergoing VATS lobectomy. For patients undergoing wedge resection for undiagnosed pulmonary nodule or metastasis from CRC, a malignant diagnosis may be confirmed post-operatively.
* Scheduled for lung resection surgery (lobectomy or wedge resection) involving only one lobe of the lung
* Willing to give consent and comply with evaluation and treatment schedule
* At least 18 years of age

Exclusion Criteria:

* Active bacterial infection or fungal infection
* Systemic administration (intravenous or oral) of steroids (within 30 days prior to study procedure)
* Chemotherapy or radiation therapy for lung cancer may not be performed for 30 days prior to the procedure
* Scheduled concurrent surgical procedure other than wedge resection or lobectomy (central venous access - e.g. port placement, mediastinoscopy with lymph node sampling, and VATS lymphadenectomy are allowed);
* Prior history of VATS or open lung surgery

• Goran Ribaric, MD, MSc, PhD, Study chair, Ethicon Endo-Surgery (Europe) GmbH