Observational - CRKL Expression at the Protein Level in Rhabdomyosarcoma Tumors by Tissue Microarray (TMA)
| Registry | NCT01496573 |
|---|---|
| Status | Completed |
| Study type | Observational |
| Enrollment | 77 (Actual) |
| Sponsor | Children's Oncology Group (Network); collaborators: National Cancer Institute (NCI) |
| Conditions | Alveolar Childhood Rhabdomyosarcoma, Childhood Rhabdomyosarcoma, Embryonal Childhood Rhabdomyosarcoma |
| Interventions | laboratory biomarker analysis (Other) |
| Dates | start 2011-12-01, primary completion 2016-05-01, completion 2016-05-01, first posted 2011-12-21, last updated 2016-05-19 |
| Locations | 1 site in United States |
Related Papers Related Patents Related Grants Related Experts
All trials for Alveolar Childhood Rhabdomyosarcoma All trials for Childhood Rhabdomyosarcoma All trials of laboratory biomarker analysis
This research trial studies biomarkers in tumor tissue samples from younger patients with rhabdomyosarcoma. Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer
PRIMARY OBJECTIVES:
I. To demonstrate CRKL expression at the protein level in rhabdomyosarcoma tumors by tissue microarray (TMA).
OUTLINE:
Archived tumor tissue samples are analyzed for CRKL expression.
| Arm | Type | Interventions | Description |
|---|---|---|---|
| Basic science (biomarker analysis) | Other: laboratory biomarker analysis | Archived tumor tissue samples are analyzed for CRKL expression. |
Sex: All
Inclusion Criteria: * Alveolar rhabdomyosarcoma and embryonal rhabdomyosarcoma specimens from the Children Oncology Group (COG) tumor microarrays (TMAs)
| Facility | City | Country | Status |
|---|---|---|---|
| Children's Oncology Group | Monrovia, California | United States |