Types of Starch and Their Effect on Blood Glucose, Appetite and Food Intake

NCT00988689 — Not applicable, Completed, 16 participants, University of Toronto

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The Effect of Different Types of Starch on Glycemic Response, Subjective Appetite and Short-term Food Intake in Young Men

Registry	NCT00988689
Status	Completed
Phase	Not applicable
Study type	Interventional; randomized, crossover, masking: single, prevention
Enrollment	16 (Actual)
Sponsor	University of Toronto (Other); collaborators: Ingredion Incorporated
Conditions	Obesity Prevention, Diabetes Prevention
Interventions	Dietary Intervention (Other)
Dates	start 2008-06-01, primary completion 2008-08-01, completion 2009-06-01, first posted 2009-10-02, last updated 2009-10-02
Locations	1 site in Canada

-Summary

The investigators hypothesize that different types of starch vary in their effects on appetite, blood sugar and food intake. In this study, subjects consumed five soups containing 50 g of whole grain, high amylose corn, regular corn or maltodextrin starches or no added starch at one week intervals. The investigators measured food intake at 120 minutes, appetite and blood sugar.

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+Arms and interventions

Arm	Type	Interventions
Soup with no added starch	Experimental	Other: Dietary Intervention
Soup + 50 g of whole grain starch	Experimental	Other: Dietary Intervention
Soup + 50 g of high amylose corn starch	Experimental	Other: Dietary Intervention
Soup + 50 g of regular corn starch	Experimental	Other: Dietary Intervention
Soup + 50 g maltodextrin starch	Experimental	Other: Dietary Intervention

Dietary Intervention (Other): soup with or without starch

+Outcome measures

Primary outcomes

Blood glucose [0-200 min]
Food Intake [at 120 min]
Appetite [0-200 min]

Secondary outcomes

Palatability of treatments [0-200 min]

+Eligibility

Sex: Male, ages: 20 Years to 30 Years, accepts healthy volunteers

Inclusion Criteria:

* Healthy males with a BMI of 20-24.9 kg/m2

Exclusion Criteria:

* Females
* Smokers
* Breakfast skippers
* Individuals with diabetes or other metabolic diseases

+Locations (1)

Facility	City	Country	Status
Department of Nutritional Studies, University of Toronto	Toronto, Ontario	Canada

+Publications

Results publication: Anderson GH, Cho CE, Akhavan T, Mollard RC, Luhovyy BL, Finocchiaro ET. Relation between estimates of cornstarch digestibility by the Englyst in vitro method and glycemic response, subjective appetite, and short-term food intake in young men. Am J Clin Nutr. 2010 Apr;91(4):932-9. doi: 10.3945/ajcn.2009.28443. Epub 2010 Feb 17. PMID 20164321

+Investigators

Harvey Anderson, Ph.D., Principal investigator, University of Toronto