3 completed, 1 active not recruiting. 4 Phase 3.
By phase and status
Follow Pentostatin: new trials by email Literature Review of Pentostatin trials Research Report on Pentostatin
Trials (filtered) newest first · largest first
All 4 trials
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|
A Study to Evaluate Axatilimab Versus Best Available Therapy in Participants With Chronic Graft Versus Host Disease After at Least 2 Prior Lines of Systemic Therapy
INCA034176, Best Available Therapy (BAT) - Chronic Graft-versus-host-disease | Phase 3 | Active not recruiting | 9 | 2025-06-04 | 2026-08-25 |
A Study of Ruxolitinib vs Best Available Therapy (BAT) in Patients With Steroid-refractory Chronic Graft vs. Host Disease (GvHD) After Bone Marrow Transplantation (REACH3)
Ruxolitinib, Extracorporeal photopheresis (ECP), Low-dose methotrexate (MTX) - Graft-versus-host Disease (GVHD) | Phase 3 | Completed | 330 | 2017-06-29 | 2025-08-12 |
Methotrexate or Pentostatin for Graft-versus-host Disease Prophylaxis in Risk-adapted Allogeneic Bone Marrow Transplantation for Hematologic Malignancies
Methotrexate, Pentostatin - Acute Lymphoblastic Leukemia, Acute Myelocytic Leukemia | Phase 3 | Completed | 6 | 2010-09-01 | 2013-03-21 |
Fludarabine, Cyclophosphamide, and Rituximab Versus Pentostatin, Cyclophosphamide, and Rituximab in Previously Untreated or Treated B-Cell Chronic Lymphocytic Leukemia Patients
Fludarabine, Cyclophosphamide, Rituximab - B-Cell Chronic Lymphocytic Leukemia | Phase 3 | Completed | 184 | 2003-12-01 | 2016-11-03 |
Conditions studied
Bronchiolitis Obliterans Syndrome (2) · Graft vs Host Disease (2) · Hodgkin Disease (1) · Leukemia, Lymphocytic, Chronic, B-Cell (1) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (1) · Leukemia, Myeloid, Acute (1) · Myelodysplastic Syndromes (1) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (1)
Sponsors
Incyte Corporation (2) · St. Jude Children's Research Hospital (1) · US Oncology Research (1)
Countries
United States (3) · Austria (2) · Belgium (2) · Czechia (2) · France (2) · Germany (2) · Greece (2) · Italy (2) · Netherlands (2) · Norway (2) · Portugal (2) · Spain (2) · Sweden (2) · Switzerland (2) · United Kingdom (2)
Top investigators
Asha Pillai, MD (1) · Craig Reynolds, MD (1) · Rodica Morariu-Zamfir (1)
Results publications
PMID 29316837, PMID 34260836, PMID 35363318, PMID 40472328, PMID 40561385, PMID 42180389
NIH funding
2016 (1)