12 completed, 4 unknown, 1 terminated. 8 Phase 4, 6 Not applicable, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 8 | Completed 4, Unknown 3, Terminated 1 |
| Not applicable | 6 | Completed 6 |
| Phase 3 | 2 | Completed 1, Unknown 1 |
Follow FloSeal Matrix: new trials by email Literature Review of FloSeal Matrix trials Research Report on FloSeal Matrix
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Hemostatic Agents in Partial Nephrectomy Standard Parenchymal Suturing, Suturing with FloSeal®, Suturing with Surgicel® - Partial Nephrectomy, Hemostatic Agents | Not applicable | Completed | Ankara University | 150 | 2023-01-02 | 2025-11-18 |
| Blood-saving Effect of Combined Intravenous Tranexamic Acid With Topical Floseal® Application Total Hip Arthroplasty intravenous application of tranexamic acid, Floseal hemostatic matrix, Normal saline - Hip Replacement, Total | Phase 4 | Unknown | Chang Gung Memorial Hospital | 90 | 2018-08-15 | 2020-01-18 |
| Combined Topical Tranexamic Acid With Floseal® in Total Knee Arthroplasty Topical tranexamic acid, Floseal®, rivaroxaban (10mg) - Osteoarthritis, Knee | Phase 4 | Completed | Chang Gung Memorial Hospital | 70 | 2017-09-12 | 2021-08-10 |
| Topical Tranexamic Acid and Floseal® in Total Knee Arthroplasty Topical tranexamic acid, Floseal®, Enoxaparin - Osteoarthritis, Knee | Phase 4 | Unknown | Chang Gung Memorial Hospital | 90 | 2016-09-01 | 2016-08-12 |
| Prospective Pilot Study of Floseal for the Treatment of Anterior Epistaxis in Patients With (HHT) Floseal, Packing - Hereditary Hemorrhagic Telangiectasia (HHT), Epistaxis | Not applicable | Completed | Unity Health Toronto | 8 | 2015-12-01 | 2020-05-28 |
| Comparison of Floseal® and Tranexamic Acid on Bleeding Control After Total Knee Arthroplasty Tranexamic acid, Floseal® - Knee Osteoarthritis | Phase 4 | Unknown | University of Sao Paulo General Hospital | 45 | 2014-02-01 | 2014-06-02 |
| Prevention of Pelvic Lymphocele by Floseal During Pelvic Lymphadenectomy for Gynecologic Cancer Floseal - Gynecologic Cancer | Phase 3 | Unknown | Ewha Womans University Mokdong Hospital | 40 | 2013-12-01 | 2015-02-11 |
| Ovarian Reserve After Ovarian Hemostasis by Floseal Matrix Floseal, Bipolar coagulation - Ovarian Cysts | Phase 3 | Completed | CHA University | 100 | 2012-12-01 | 2014-06-25 |
| Intrauterine Use of FloSeal: Is it Safe and Useful? Hysterectomy with FloSeal - Operative Hemorrhage | Not applicable | Completed | David L Zisow MD LLC | 14 | 2012-12-01 | 2016-01-21 |
| Study to Compare the Addition of Floseal to Our Standard of Care to Control Post Operative Bleeding in TKR Floseal - Intraoperative Bleeding, Post-operative Bleeding | Phase 4 | Completed | Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal | 132 | 2012-01-01 | 2017-08-09 |
| Efficacy and Safety of FLOSEAL for Hemostasis in Total Knee Arthroplasty Standard of Care, FLOSEAL Hemostatic Matrix + Standard of care - Knee Replacement Surgery, Osteoarthritis | Phase 4 | Completed | Baxter Healthcare Corporation | 137 | 2011-09-01 | 2014-06-06 |
| Comparison of Hemostatic Matrix and Bipolar Coagulation in Surgical Treatment of Endometriomas Bipolar electrocautery for ovarian hemostasis, hemostatic matrix (FloSeal) - Ovarian Reserve, Endometrioma | Not applicable | Completed | Ankara University | 30 | 2010-09-01 | 2011-06-22 |
| Floseal Treatment for Posterior Epistaxis Study Floseal - Epistaxis | Not applicable | Completed | Ottawa Hospital Research Institute | 20 | 2010-04-01 | 2015-01-26 |
| Effect on Bleeding When Using FloSeal Matrix™ in Subjects Undergoing Endoscopic Vein Harvest (EVH) FloSeal Matrix - Bleeding | Phase 4 | Terminated | Duke University | 50 | 2009-06-01 | 2014-03-05 |
| FloSeal in CRS and HIPEC FloSeal - Peritoneal Carcinomatosis | Completed | Maisonneuve-Rosemont Hospital | 86 | 2008-01-01 | 2015-02-25 | |
| The Use of FLOSEAL to Reduce Bleeding in Total Knee Replacement Surgery Hemostatic Matrix - Blood Loss | Phase 4 | Completed | Hospital for Special Surgery, New York | 196 | 2007-10-01 | 2017-12-12 |
| FloSeal Tubeless Exit Versus Cope Loop Nephrostomy Versus Fascial Stitch Following Percutaneous Nephrolithotripsy Floseal, Cope Loop, Fascial Stitch - Kidney Calculi | Not applicable | Completed | University of California, Irvine | 59 | 2004-06-01 | 2016-12-13 |
Hemorrhage (4) · Osteoarthritis, Knee (3) · Blood Loss, Surgical (2) · Epistaxis (2) · Carcinoma, Renal Cell (1) · Endometriosis (1) · Kidney Calculi (1) · Osteoarthritis (1) · Ovarian Cysts (1) · Peritoneal Neoplasms (1) · Postoperative Hemorrhage (1) · Telangiectasia, Hereditary Hemorrhagic (1)
Chang Gung Memorial Hospital (3) · Ankara University (2) · Baxter Healthcare Corporation (1) · CHA University (1) · Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal (1) · David L Zisow MD LLC (1) · Duke University (1) · Ewha Womans University Mokdong Hospital (1) · Hospital for Special Surgery, New York (1) · Maisonneuve-Rosemont Hospital (1) · Ottawa Hospital Research Institute (1) · Unity Health Toronto (1) · University of California, Irvine (1) · University of Sao Paulo General Hospital (1)
United States (5) · Canada (3) · Taiwan (3) · South Korea (2) · Turkey (Türkiye) (2) · Brazil (1)
Jun-Wen Wang, MD (2) · Camilo P Helito, M.D. (1) · David L Zisow, MD (1) · Gilberto L Camanho, Ph.D. (1) · Ildiko Szabo, MD, MBA (1) · James E Lowe, MD (1) · John Lee, MD, MSc (1) · Jose R Pecora, Ph.D. (1) · Julio C Fernandes, MDMScMBAPhD (1) · Jun-Wen Wang (1) · Luis Eduardo P Tirico, M.D. (1) · Marcelo B Bonadio, M.D. (1) · Marco K Demange, Ph.D. (1) · Mark P Figgie, MD (1) · Michael K Louie, MD (1)
PMID 12559270, PMID 15780356, PMID 19683266, PMID 23754469, PMID 24903197, PMID 25282367, PMID 25615258, PMID 27279548, PMID 27431979, PMID 27572274, PMID 29277887, PMID 29410886, PMID 30613663, PMID 30817286, PMID 31040606, PMID 31258357, PMID 31615556, PMID 31778430, PMID 32065869, PMID 33511201, PMID 35346519, PMID 35407375, PMID 37094827, PMID 39470887, PMID 40180849, PMID 40226071, PMID 40637905
2014 (1)