15 completed, 2 not yet recruiting, 1 active not recruiting, 1 recruiting. 19 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 19 | Completed 15, Not yet recruiting 2, Active not recruiting 1, Recruiting 1 |
| Phase 3 | 2 | Active not recruiting 1, Completed 1 |
| Phase 1 | 1 | Completed 1 |
Follow Trichotillomania: new trials by email Literature Review of Trichotillomania trials Research Report on Trichotillomania
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Semaglutide (Wegovy) Treatment for Trichotillomania Semaglutide - Trichotillomania (Hair-Pulling Disorder), Trichotillomania | Phase 2 | Not yet recruiting | University of Chicago | 10 | 2026-06-01 | 2026-06-10 |
| Aripiprazole in Body Focused Repetitive Behaviors Placebo, Aripiprazole - Trichotillomania (Hair-Pulling Disorder), Dermatillomania | Phase 2 | Not yet recruiting | University of Chicago | 100 | 2026-06-01 | 2025-10-02 |
| Efficacy of Valbenazine for the Treatment of Trichotillomania in Adults Valbenazine Oral Capsule, Placebo Oral capsule - Trichotillomania (Hair-Pulling Disorder) | Phase 2 | Recruiting | Yale University | 20 | 2024-02-02 | 2026-02-03 |
| Behavioral Treatment and Memantine in Body Focused Repetitive Behaviors Memantine, ComB Behavioral Therapy - Skin-Picking, Trichotillomania (Hair-Pulling Disorder) | Phase 2 / Phase 3 | Active not recruiting | University of Chicago | 26 | 2023-08-02 | 2026-07-07 |
| Epidiolex in Obsessive Compulsive Disorder and Related Disorders Cannabidiol - Obsessive-Compulsive Disorder, Trichotillomania (Hair-Pulling Disorder) | Phase 2 | Completed | University of Chicago | 4 | 2022-04-14 | 2026-07-29 |
| Memantine in Body Focused Repetitive Behaviors Placebo, Memantine - Trichotillomania (Hair-Pulling Disorder), Dermatillomania | Phase 2 | Completed | University of Chicago | 100 | 2021-06-15 | 2024-09-19 |
| A Study in Patients With Trichotillomania SXC-2023, Placebo - Trichotillomania | Phase 2 | Completed | Promentis Pharmaceuticals, Inc. | 128 | 2018-12-19 | 2021-10-28 |
| Dronabinol in Trichotillomania and Other Body Focused Repetitive Behaviors Dronabinol, Placebo - Trichotillomania, Skin-Picking | Phase 2 / Phase 3 | Completed | University of Chicago | 50 | 2018-10-01 | 2022-06-02 |
| Milk Thistle in Trichotillomania in Children and Adults Milk Thistle, Placebo - Trichotillomania, Hair Pulling Disorder | Phase 2 | Completed | University of Chicago | 22 | 2015-03-01 | 2020-11-20 |
| Inositol in Trichotillomania Inositol, Placebo - Trichotillomania, Hair Pulling | Phase 2 | Completed | University of Chicago | 38 | 2013-05-01 | 2023-02-23 |
| Stepped Care in the Treatment of Trichotillomania StopPulling.com - Trichotillomania | Phase 2 | Completed | American University | 60 | 2010-08-01 | 2013-05-27 |
| Marinol in Trichotillomania or Obsessive Compulsive Disorder Dronabinol - Trichotillomania, Obsessive Compulsive Disorder | Phase 2 | Completed | University of Chicago | 14 | 2010-04-01 | 2023-02-23 |
| N-Acetylcysteine for Pediatric Trichotillomania N-Acetylcysteine, Placebo - Trichotillomania, Hair Pulling | Phase 2 | Completed | Yale University | 39 | 2009-10-01 | 2014-07-25 |
| Testing a New Therapy for Trichotillomania Acceptance enhanced behavior therapy (AEBT), Psychoeducation and supportive therapy (PST) - Trichotillomania | Phase 2 | Completed | University of Wisconsin, Milwaukee | 85 | 2009-03-01 | 2021-10-05 |
| Cognitive Behavioral Therapy for Trichotillomania Cognitive Behavioral Therapy - Trichotillomania | Phase 1 / Phase 2 | Completed | Massachusetts General Hospital | 38 | 2008-11-01 | 2012-06-20 |
| Naltrexone in the Treatment of Trichotillomania Naltrexone, Placebo - Trichotillomania | Phase 2 | Completed | University of Chicago | 51 | 2008-08-01 | 2023-02-23 |
| Trichotillomania: Group Cognitive-Behavioral Therapy Cognitive-behavioral therapy., Supportive therapy. - Trichotillomania | Phase 2 | Completed | University of Sao Paulo | 44 | 2008-01-01 | 2015-08-19 |
| N-Acetyl Cysteine in Trichotillomania Placebo, N-Acetyl Cysteine - Trichotillomania | Phase 2 | Completed | University of Chicago | 50 | 2006-07-01 | 2023-02-23 |
| Awareness Enhancement and Monitoring Device for Treatment of Trichotillomania Awareness Enhancement and Monitoring Device for Treatment of Trichotillomania - Trichotillomania | Phase 2 | Completed | University of Michigan | 33 | 2005-01-01 | 2016-07-22 |
Excoriation Disorder (6) · Disruptive, Impulse Control, and Conduct Disorders (2) · Obsessive-Compulsive Disorder (2) · Hoarding (1) · Hoarding Disorder (1) · Tourette Syndrome (1) · Trichomonas Infections (1)
Anxiety Disorders (19) · Mental Disorders (19) · Disruptive, Impulse Control, and Conduct Disorders (17) · Obsessive-Compulsive Disorder (17) · Behavior (6) · Behavioral Symptoms (6) · Self-Injurious Behavior (6) · Basal Ganglia Diseases (1) · Brain Diseases (1) · Central Nervous System Diseases (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Genetic Diseases, Inborn (1) · Heredodegenerative Disorders, Nervous System (1) · Infections (1) · Movement Disorders (1)
Acetylcysteine (2) · Cognitive Behavioral Therapy (2) · Dronabinol (2) · Memantine (2) · Palliative Care (2) · Sugars (2) · Acceptance and Commitment Therapy (1) · Aripiprazole (1) · Behavior Therapy (1) · Cannabidiol (1) · Inositol (1) · Monitoring, Physiologic (1) · Naltrexone (1) · Silymarin (1) · milk-thistle extract (1)
University of Chicago (11) · Yale University (2) · American University (1) · Massachusetts General Hospital (1) · Promentis Pharmaceuticals, Inc. (1) · University of Michigan (1) · University of Sao Paulo (1) · University of Wisconsin, Milwaukee (1)
United States (17) · Brazil (1)
Jon E Grant, MD, JD, MPH (4) · Jon E Grant, JD, MD, MPH (3) · Dean Brostowin (1) · Douglas W. Woods, PhD (1) · Gregory Chasson, PhD (1) · Jon E Grant, M.D. (1) · Jon E Grant, MD, JD (1) · Jon E Grant, MD,JD,MPH (1) · Jon Grant, JD, MD, MPH (1) · Joseph A Himle, PhD (1) · Michael H. Bloch, M.D., M.S. (1) · Michael H. Bloch, MD (1) · Nancy Keuthen, PhD (1)
PMID 34582562, PMID 23251869, PMID 19581567, PMID 21456040, PMID 21590520, PMID 23452680, PMID 23452681, PMID 25271779, PMID 26139231, PMID 27724833, PMID 34825898, PMID 38330639, PMID 38761558
R01MH080966 (1), R42MH077362 (1)