5 completed, 1 terminated. 6 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Completed 5, Terminated 1 |
| Phase 2 | 3 | Completed 3 |
Follow Scleritis: new trials by email Literature Review of Scleritis trials Research Report on Scleritis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Gevokizumab for Active Scleritis Gevokizumab - Scleritis | Phase 1 / Phase 2 | Completed | National Eye Institute (NEI) | 8 | 2013-03-01 | 2018-07-06 |
| Sirolimus Injections for Autoimmune Scleritis Sirolimus - Scleritis | Phase 1 / Phase 2 | Completed | National Eye Institute (NEI) | 5 | 2012-01-01 | 2020-06-19 |
| Iontophoresis Delivery of Dexamethasone Phosphate for Non-infectious, Non-necrotizing Anterior Scleritis, Phase 1 Dose-varying Study Dexamethasone Phosphate Ophthalmic Solution (EGP-437), Dexamethasone phosphate ophthalmic solution - Non-infectious, Non-necrotizing Anterior Scleritis | Phase 1 | Completed | John Kempen | 18 | 2012-01-01 | 2016-04-21 |
| Rituximab in the Treatment of Scleritis and Non-Infectious Orbital Inflammation Rituximab - Scleritis, Orbital Disease | Phase 1 / Phase 2 | Completed | Oregon Health and Science University | 20 | 2007-01-01 | 2013-08-16 |
| Study Evaluating PSI-697 in Patients With Scleritis PSI-697 - Scleritis | Phase 1 | Terminated | Wyeth is now a wholly owned subsidiary of Pfizer | 12 | 2006-09-01 | 2009-09-09 |
| Infliximab to Treat Non-Infectious Scleritis Infliximab - Scleritis | Phase 1 | Completed | National Eye Institute (NEI) | 5 | 2003-12-23 | 2017-07-02 |
Orbital Diseases (1)
Eye Diseases (6) · Scleral Diseases (6)
2-(4-chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo(H)quinoline-4-carboxylic acid (1) · Infliximab (1) · Rituximab (1) · Sirolimus (1)
National Eye Institute (NEI) (3) · John Kempen (1) · Oregon Health and Science University (1) · Wyeth is now a wholly owned subsidiary of Pfizer (1)
United States (5)
Hatice N Sen, M.D. (2) · Eric B Suhler, MD (1) · James T Rosenbaum, MD (1)