7 completed, 6 recruiting, 1 terminated, 1 withdrawn. 4 Not applicable, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Completed 2, Recruiting 1, Withdrawn 1 |
| Phase 2 | 4 | Completed 2, Recruiting 2 |
Follow Polyendocrinopathies, Autoimmune: new trials by email Literature Review of Polyendocrinopathies, Autoimmune trials Research Report on Polyendocrinopathies, Autoimmune
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Telehealth Music Therapy for Adults With Endocrine Disorder and Depression Telehealth Resource Oriented Music Therapy - Type 1 Diabetes, Hashimoto Disease | Not applicable | Recruiting | Appalachian State University | 10 | 2026-07-16 | 2026-07-30 |
| Randomized Stepped Wedge Study of Emapalumab in APECED Enteritis Emapalumab - Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy Enteritis | Phase 2 | Recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 30 | 2025-11-12 | 2026-09-09 |
| Treatment Study in Patients Treated With Both Insulin & Hydrocortisone OD dual-release Hydrocortisone, TID Hydrocortisone - Diabetes Mellitus, Adrenal Insufficiency | Not applicable | Withdrawn | Vastra Gotaland Region | 2025-01-01 | 2026-07-07 | |
| Analysis of the Role of AIRE in Autoimmune Neurological Diseases Associated With Autoantibodies Test for AQP4, AChR, LGI1, and CASPR2 autoantibodies using cell-based assay, AIRE single gene sequencing, Molecular typing of HLA class I and II alleles - AIRE Deficiency | Recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 40 | 2024-11-06 | 2025-04-24 | |
| Evaluate the Efficacy and Safety of Ruxolitinib on Hair Regrowth in Patients With Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED)-Associated Alopecia Areata Ruxolitinib - Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (Apeced), Alopecia Areata | Phase 2 | Recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 70 | 2023-01-18 | 2026-06-22 |
| Prevalence and Genetic Alternation of Autoimmune Polyglandular Syndrome Type II in Taiwan no intervention - Autoimmune Polyendocrine Syndrome Type II | Recruiting | National Taiwan University Hospital | 650 | 2022-01-01 | 2022-10-13 | |
| Conception of a Diagnosis, Prognosis and Therapeutic Decision Tool for Patients With Autoimmunity and Inflammation Collection of samples - Autoimmune Lymphoproliferative Syndrome, Autoimmune Cytopenia | Completed | Institut National de la Santé Et de la Recherche Médicale, France | 325 | 2021-09-07 | 2026-09-18 | |
| Characterization of the Fungal Origins in the Autoimmune Polyendocrinopathy of Type 1 Compared With the Autoimmune Polyendocrinopathies of Type 2 Polyendocrinopathies, Autoimmune | Terminated | University Hospital, Lille | 7 | 2021-04-23 | 2026-05-22 | |
| CAMB/MAT2203 in Patients With Mucocutaneous Candidiasis Amphotericin B - Candidiasis, Chronic Mucocutaneous | Phase 2 | Completed | Matinas BioPharma Nanotechnologies, Inc. | 4 | 2016-09-27 | 2024-08-07 |
| Depressed AIRE Gene Expression Causes Immune Cell Dysfunction & Autoimmunity in Down Syndrome Phlebotomy - Down Syndrome, Polyendocrinopathies, Autoimmune | Not applicable | Completed | University of Colorado, Denver | 45 | 2015-10-19 | 2022-04-19 |
| Tyrosine Hydroxylase Antibody Levels in Autoimmune Polyglandular Syndrome Type 1 Associated Keratitis Detection of autoantibodies - Autoimmune Polyglandular Syndrome Type I, Autoimmune Keratitis | Not applicable | Completed | The Eye Center and The Eye Foundation for Research in Ophthalmology | 16 | 2014-01-01 | 2020-05-05 |
| Participation in a Research Registry for Immune Disorders Primary Immunodeficiencies, APECED | Completed | National Human Genome Research Institute (NHGRI) | 716 | 2013-09-30 | 2023-07-20 | |
| Natural History of Individuals With Immune System Problems That Lead to Fungal Infections Chronic Mucocutaneous Candidiasis, Invasive Aspergillosis | Recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 1200 | 2012-11-05 | 2026-08-24 | |
| Evaluation Genotypic, Phenotypic and Prognosis APECED Syndrome APECED | Completed | University Hospital, Lille | 29 | 2009-07-30 | 2025-12-26 | |
| Comparing Pump With Subcutaneous Injection Delivery of PTH 1-34 in the Management of Chronic Hypoparathyroidism Synthetic Human Parathyroid Hormone 1-34 pump - Hypoparathyroidism, Hypocalcemia | Phase 2 | Completed | National Institutes of Health Clinical Center (CC) | 21 | 2008-08-22 | 2026-03-04 |
Candidiasis, Chronic Mucocutaneous (3) · Autoimmune Diseases (2) · Diabetes Mellitus (2) · Diabetes Mellitus, Type 1 (2) · Primary Immunodeficiency Diseases (2) · Addison Disease (1) · Adrenal Insufficiency (1) · Alopecia (1) · Alopecia Areata (1) · Arthritis, Juvenile (1) · Autoimmune Diseases of the Nervous System (1) · Autoimmune Lymphoproliferative Syndrome (1) · Autoimmune enteropathy (1) · Depression (1)
Immune System Diseases (15) · Endocrine System Diseases (14) · Autoimmune Diseases (13) · Pathological Conditions, Signs and Symptoms (5) · Skin and Connective Tissue Diseases (5) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4) · Genetic Diseases, Inborn (4) · Infections (4) · Metabolic Diseases (4) · Nutritional and Metabolic Diseases (4) · Pathologic Processes (4) · Skin Diseases (4) · Bacterial Infections and Mycoses (3) · Candidiasis (3) · Chronic Disease (3)
Alleles (1) · Amphotericin B (1) · Emapalumab (1) · Phlebotomy (1) · ruxolitinib (1)
National Institute of Allergy and Infectious Diseases (NIAID) (3) · University Hospital, Lille (2) · Appalachian State University (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Institut National de la Santé Et de la Recherche Médicale, France (1) · Matinas BioPharma Nanotechnologies, Inc. (1) · National Human Genome Research Institute (NHGRI) (1) · National Institutes of Health Clinical Center (CC) (1) · National Taiwan University Hospital (1) · The Eye Center and The Eye Foundation for Research in Ophthalmology (1) · University of Colorado, Denver (1) · Vastra Gotaland Region (1)
United States (8) · France (3) · Italy (1) · Sweden (1) · Taiwan (1)
Michail S Lionakis, M.D. (3) · Alexandra Freeman, MD (1) · Dimitrios Chantzichristos, MD PhD (1) · Elizabeth K Garabedian, R.N. (1) · Emmanuelle Proust-Lemoine, MD (1) · Karen K Winer, M.D. (1) · Melody Schwantes, PhD, MT-BC (1) · Michael E Yeager, Ph.D. (1) · Raffaele Iorio, MD (1) · Shyang-Rong Shih, MD, PhD (1)
PMID 22090268, PMID 24948345, PMID 29619656, PMID 31095438, PMID 32557834, PMID 35699443, PMID 36875114, PMID 38605470