18 terminated, 15 completed, 6 recruiting, 5 unknown. 50 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 50 | Terminated 18, Completed 15, Recruiting 6, Unknown 5, Withdrawn 5, Active not recruiting 1 |
Follow Musculoskeletal Abnormalities: new trials by email Literature Review of Musculoskeletal Abnormalities trials Research Report on Musculoskeletal Abnormalities
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| GLP-1R Actions on Muscle and the Skeleton Tirzepatide, Lifestyle toolkit - Musculoskeletal Abnormalities, Obesity | Phase 4 | Recruiting | Pennington Biomedical Research Center | 50 | 2025-10-09 | 2026-08-27 |
| Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery Methadone hydrochloride, Fentanyl/Hydromorphone - Cleft Palate, Pain | Phase 4 | Recruiting | Duke University | 60 | 2025-06-04 | 2026-04-14 |
| Sinus Tarsi Implant as an Adjuvant Procedure to Medial Displacement Calcaneal Osteotomy in the Treatment of Mobile Adult Acquired Flatfoot Deformity ProStop, sinus tarsi implant (STI), Conventional surgery - Acquired Adult Flatfoot Deformity, Flat Foot | Phase 4 | Recruiting | Region Skane | 130 | 2024-07-31 | 2025-12-02 |
| Nebulized Dexmedetomidine Combined With Ketamine Versus Nebulized Dexmedetomidine for Cleft Palate Nebulization of dexmedetomidine and ketamine, Nebulization of dexmedetomidine - Sedation, Emergence Delirium | Phase 4 | Recruiting | Assiut University | 60 | 2024-04-10 | 2025-10-03 |
| Multifidus Cervicis Plane Block Vs. Sham Block For Posterior Cervical Spine Fusion Surgery Bupivacaine Hcl 0.25% Inj, Normal saline - Cervical Spine Fusion | Phase 4 | Recruiting | Hartford Hospital | 38 | 2023-12-12 | 2025-09-05 |
| Serratus Intercostal Block Versus Epidural/Port Infiltration Analgesia in Eventration: Prospective Non Inferiority Study undergo, ultrasound, Local anesthetic - Eventration, Regional Anesthesia | Phase 4 | Completed | Hospital del Rio Hortega | 160 | 2023-10-01 | 2026-06-08 |
| Pre-Operative Ketamine Infusion for Post Operative Pain Control After Revision Spinal Surgery Ketamine Hydrochloride - Revision Spine Surgery, Fusion of Spine | Phase 4 | Unknown | AXIS Spine Center- a division of Northwest Specialty Hospital | 40 | 2023-09-18 | 2023-10-04 |
| Clubfoot Tenotomy Trial Jet injection of 1% lidocaine, 4% liposomal lidocaine cream - Clubfoot | Phase 4 | Completed | Vanderbilt University Medical Center | 107 | 2021-06-01 | 2026-05-05 |
| Clonidine for Tourniquet-related Pain in Children Catapresan, Saline - Polydactyly Toe, Thumb Hypoplasia | Phase 4 | Unknown | Odense University Hospital | 20 | 2021-03-01 | 2021-09-10 |
| Trigger Point Injections in Anterior Cervical Surgery Trigger point injection with bupivacaine, Trigger point injection with normal saline, Lidocaine skin wheal - Myofacial Pain, Pain, Neck | Phase 4 | Completed | George Washington University | 60 | 2020-11-05 | 2026-08-13 |
| Effects of Antiemetic Agents in Orthognathic Surgery Patients Intravenous drug - Emesis, Postoperative, Maxillofacial Abnormalities | Phase 4 | Completed | Bezmialem Vakif University | 66 | 2020-04-14 | 2024-06-12 |
| Intravenous Dexamethasone to Prolong Caudal Block Analgesia in Children Undergoing Hip Surgery Dexamethasone, Normal Saline, Caudal Block Anesthesia - Pain, Postoperative, Developmental Dysplasia of the Hip | Phase 4 | Completed | National Institute of Neurology, Tunisia | 54 | 2019-09-01 | 2026-10-26 |
| The Use of Fibrin Sealant to Reduce Post Operative Pain in Cleft Palate Surgery Tisseel - Cleft Palate | Phase 4 | Withdrawn | University of Alberta | 2019-09-01 | 2022-05-20 | |
| Evaluation of Trigeminal Nerve Blockade Ropivacaine, Sham Comparator - Mouth Abnormalities, Cleft Palate | Phase 4 | Active not recruiting | University of Florida | 40 | 2018-11-20 | 2026-07-21 |
| The Use of Gastrografin to Help Alleviate Bowel Obstruction in Gastroschisis Patients. Gastrografin - Gastroschisis, Bowel Obstruction | Phase 4 | Withdrawn | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2018-08-03 | 2023-11-01 | |
| Assessment of Gait After Dysport Treatment Dysport - Equinovarus; Acquired | Phase 4 | Completed | Albert Einstein Healthcare Network | 11 | 2018-06-11 | 2020-03-02 |
| A Study of Crisaborole Ointment 2%; Crisaborole Vehicle; TCS and TCI in Subjects Aged ≥ 2 Years, With Mild-moderate AD Crisaborole ointment, 2%, Hydrocortisone butyrate cream, 0.1%, Pimecrolimus cream, 1% - Atopic Dermatitis | Phase 4 | Terminated | Pfizer | 237 | 2018-04-27 | 2022-01-10 |
| Dexmedetomidine vs Placebo for Pediatric Cleft Palate Repair Dexmedetomidine, Placebo - Cleft Palate | Phase 4 | Withdrawn | Baylor College of Medicine | 2017-12-31 | 2019-02-05 | |
| Evaluation of Glycerin Suppositories to Improve Bowel Function in Gastroschisis Glycerin Suppository - Gastroschisis | Phase 4 | Terminated | Indiana University | 16 | 2017-10-01 | 2021-10-12 |
| Human Fibrinogen Concentrate in Pediatric Cardiac Surgery RiaStAP, Saline - Hypofibrinogenemia, Afibrinogenemia | Phase 4 | Completed | Nicklaus Children's Hospital f/k/a Miami Children's Hospital | 30 | 2017-06-01 | 2021-09-16 |
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Hip Dislocation, Congenital (18) · Osteoarthritis (17) · Osteonecrosis (17) · Arthritis, Rheumatoid (13) · Collagen Diseases (11) · Slipped Capital Femoral Epiphyses (11) · Cleft Palate (6) · Funnel Chest (5) · Gastroschisis (4) · Klippel-Feil Syndrome (4) · Pain (4) · Agnosia (3) · Clubfoot (3) · Flatfoot (3) · Congenital Abnormalities (2)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (50) · Musculoskeletal Diseases (50) · Congenital Abnormalities (48) · Pathological Conditions, Signs and Symptoms (34) · Bone Diseases (32) · Bone Diseases, Developmental (25) · Pathologic Processes (23) · Developmental Dysplasia of the Hip (18) · Joint Diseases (17) · Necrosis (17) · Rheumatic Diseases (17) · Arthritis (16) · Skin and Connective Tissue Diseases (16) · Connective Tissue Diseases (15)
Sodium Chloride (6) · Saline Solution (4) · Ketamine (3) · Tranexamic Acid (3) · Analgesia, Patient-Controlled (2) · Bupivacaine (2) · Dexamethasone (2) · Fentanyl (2) · Hydromorphone (2) · Anesthesia, Conduction (1) · Anesthetics, Local (1) · Arthroplasty (1) · Arthroplasty, Replacement, Hip (1) · Clonidine (1) · Desflurane (1)
DePuy International (14) · Baylor College of Medicine (2) · The Catholic University of Korea (2) · AXIS Spine Center- a division of Northwest Specialty Hospital (1) · Albert Einstein Healthcare Network (1) · Assiut University (1) · Bezmialem Vakif University (1) · Boston Children's Hospital (1) · DePuy Orthopaedics (1) · Duke University (1) · George Washington University (1) · Hartford Hospital (1) · Hospital Universitari Vall d'Hebron Research Institute (1) · Hospital del Rio Hortega (1) · Indiana University (1)
United States (20) · United Kingdom (8) · Germany (5) · Italy (4) · Spain (4) · South Korea (3) · Canada (2) · Czechia (2) · New Zealand (2) · Portugal (2) · Sweden (2) · Switzerland (2) · Australia (1) · Austria (1) · China (1)
Alan Ladd, M.D. (1) · Alberto Esquenazi, MD (1) · Benjamin Padilla, MD (1) · Borja Villanueva Figueredo, MD (1) · Cameron R Smith, MD, PhD (1) · Chris D. Glover, MD (1) · Chris Glover, MD (1) · Christopher Tirotta, MD (1) · Dave Whalen, BS, DC (1) · Francesc Vallribera Valls, MD,PhD (1) · Guilherme C Arantes (1) · Gwo-Chin Lee, MD (1) · Ida Osbeck, MD (1) · Jaret L Olson, MD FRCSC (1) · Jeffrey Martus, MD (1)
PMID 18547784, PMID 20458640, PMID 29318534, PMID 30935731, PMID 32620262, PMID 35029841, PMID 35080267, PMID 35305111, PMID 36214650, PMID 39824505
2018 (1), 2023 (1), R03HD090617 (1)