20 completed, 14 unknown, 6 recruiting, 5 not yet recruiting. 56 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 56 | Completed 20, Unknown 14, Recruiting 6, Not yet recruiting 5, Terminated 5, Withdrawn 3, Active not recruiting 2, Suspended 1 |
Follow Multiple Organ Failure: new trials by email Literature Review of Multiple Organ Failure trials Research Report on Multiple Organ Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hemoadsorpion in Patients With Septic Shock: Efficacy and Safety Evaluation Efferon LPS, Toramyxin PMX 20R, Jafron HA 330 - Septic Shock | Not applicable | Not yet recruiting | Moscow Multidisciplinary Clinical Center "Kommunarka" | 76 | 2026-06-25 | 2026-07-02 |
| Efferon LPS Hemoadsorption in Cardiac Surgery Patients Efferon LPS - Cardiac Disease, Multiple Organ Dysfunction Syndrome | Not applicable | Recruiting | Efferon JSC | 60 | 2026-04-22 | 2026-08-26 |
| Extracorporeal Blood Purification Using Oxiris for Septic Shock (EXPLORE Study) Oxiris Filter (Blood Purification Device) - Septic Shock, Multi Organ Failure | Not applicable | Not yet recruiting | Pusan National University Yangsan Hospital | 62 | 2026-02-01 | 2026-01-14 |
| Safety, Tolerability and Performance of the NucleoCapture Extracorporeal Therapeutic Apheresis Device in the Reduction of Circulating cfDNA/NETs in Subjects With Pancreatitis NucleoCapture device - Acute Pancreatitis, Organ Failure, Multiple | Not applicable | Not yet recruiting | Liverpool University Hospitals NHS Foundation Trust | 20 | 2025-12-01 | 2025-03-20 |
| Evaluating the Utility of RELiZORB™ for Treating Feeding Intolerance in Critically Ill Adults With Multi-Organ Failure RELiZORB™, Placebo - Multi Organ Failure, Exocrine Pancreatic Insufficiency | Not applicable | Active not recruiting | Inova Health Care Services | 32 | 2025-05-07 | 2026-10-13 |
| Efficacy of Add-on Plasma Exchange As an Adjunctive Strategy Against Septic Shock Therapeutic Plasma Exchange (TPE) - Septic Shock | Not applicable | Recruiting | Hannover Medical School | 274 | 2025-02-19 | 2025-03-13 |
| Hemoperfusion Efferon LPS During Cardiac Surgery Using Cardiopulmonary Bypass Efferon LPS - Cardiac Disease, Multiple Organ Dysfunction Syndrome | Not applicable | Terminated | Efferon JSC | 14 | 2024-11-11 | 2025-12-09 |
| OXiris for Abdominal SEptic Shock (OASES Study) CRRT filter - Septic Shock, Abdominal Sepsis | Not applicable | Not yet recruiting | RenJi Hospital | 192 | 2024-08-15 | 2024-07-16 |
| Evaluation of the Efficiency of Intermittent Enteral Nutrition on Multi-organ Failure From Patients With Mechanical Ventilation in Intensive Care Unit Intermittent enteral nutrition - Intermittent Fasting, Septic Shock | Not applicable | Completed | University Hospital, Rouen | 174 | 2024-07-09 | 2026-09-28 |
| Feasibility Pilot Study to Evaluate the Safety and Performance of the MEX-CD1 Medical Device in ACLF MEX-CD1 Dialysis - Acute on Chronic Liver Failure, Multiple Organ Failure | Not applicable | Completed | Mexbrain | 11 | 2024-06-21 | 2026-04-29 |
| The Impact and Effect of Traditional Chinese Medicine Treatment on Organ Failure in Critically Ill Patients traditional Chinese medicine, Routine ICU care, historical Routine ICU care - Organ Failure, Multiple, Indigestion | Not applicable | Recruiting | China Medical University Hospital | 350 | 2024-05-07 | 2024-06-11 |
| Impact of Fourier Transform Infrared Spectroscopy (FTIRS) in ICUs FTIR results - Organ Failure, Multiple | Not applicable | Recruiting | University Hospital, Caen | 900 | 2024-01-08 | 2025-07-24 |
| Intermittent ADVOS vs. Hemodialysis in Non-intensive Care Patients With Liver Dysfunction Hemodialysis, ADVOS - Liver Cirrhosis, Kidney Failure, Acute | Not applicable | Unknown | University Medical Center Mainz | 14 | 2023-06-01 | 2023-11-13 |
| MAnual Lymphatic DrAinage to iMprove the outcomE of Patients After Septic Shock Manual Lymphatic Drainage, Usual Care - Sepsis, Multiorgan Failure | Not applicable | Completed | University Hospital Ostrava | 24 | 2023-06-01 | 2025-12-12 |
| Trial of Indication-Based Transfusion of Red Blood Cells in ECMO Red blood cell transfusion - Extracorporeal Membrane Oxygenation, Red Blood Cell Transfusion | Not applicable | Active not recruiting | Boston Children's Hospital | 228 | 2023-04-14 | 2026-07-02 |
| Hemoperfusion in Critical Patients With Septic Multiorgan Dysfunction Syndrome. Extracorporeal support with haemoperfusion, Conventional treatment - Hemoperfusion, Multiorgan Failure | Not applicable | Recruiting | Hospital Clinic of Barcelona | 48 | 2023-03-01 | 2025-06-10 |
| Evaluation of the Effectiveness of Extracorporeal Methods for Removing Mediators of Systemic Inflammation renal replacement therapy - Renal Failure Acute, Multiple Organ Failure | Not applicable | Unknown | Petrovsky National Research Centre of Surgery | 20 | 2021-11-25 | 2022-02-03 |
| The Role of Blood Purification by Hemoadsorption as Adjunctive Treatment in Children With Septic Shock HA330 hemoadsorption technique - Septic Shock, Multi Organ Failure | Not applicable | Completed | Chulalongkorn University | 10 | 2021-07-01 | 2022-06-02 |
| Early Renal Replacement Therapy in COVID 19 Patients With AKI Does it Improve the Outcome? haemodialysis - Multi Organ Failure | Not applicable | Completed | Sohag University | 100 | 2021-06-01 | 2022-03-10 |
| ECMOsorb Trial - Impact of a VA-ECMO in Combination With CytoSorb in Critically Ill Patients With Cardiogenic Shock CytoSorb, VA-ECMO only - Cardiogenic Shock | Not applicable | Completed | Christian Schulze | 42 | 2021-05-21 | 2026-02-04 |
Showing 20 of 56. Sign in to see all of them.
Sepsis (12) · Shock, Septic (12) · Critical Illness (4) · Acute Kidney Injury (3) · Pancreatitis (3) · Renal Insufficiency (3) · Respiratory Insufficiency (3) · Burns (2) · Heart Diseases (2) · Hepatic Encephalopathy (2) · Kidney Failure, Chronic (2) · Liver Cirrhosis (2) · Multiple Sclerosis (2) · Obesity (2)
Pathologic Processes (56) · Pathological Conditions, Signs and Symptoms (56) · Shock (55) · Infections (23) · Inflammation (21) · Systemic Inflammatory Response Syndrome (20) · Digestive System Diseases (12) · Female Urogenital Diseases (9) · Female Urogenital Diseases and Pregnancy Complications (9) · Kidney Diseases (9) · Male Urogenital Diseases (9) · Urogenital Diseases (9) · Urologic Diseases (9) · Sepsis (8) · Disease Attributes (7)
Plasma Exchange (2) · Albumins (1) · Antioxidants (1) · Bumetanide (1) · Conservative Treatment (1) · Continuous Renal Replacement Therapy (1) · Dialysis (1) · Diuretics (1) · Early Ambulation (1) · Early Goal-Directed Therapy (1) · Erythrocyte Transfusion (1) · Fecal Microbiota Transplantation (1) · Furosemide (1) · Glutamine (1) · Hematologic Tests (1)
Efferon JSC (2) · Fujian Medical University (2) · Hospices Civils de Lyon (2) · University Hospital Ostrava (2) · University of Pecs (2) · University of Rostock (2) · ASST Fatebenefratelli Sacco (1) · Advanced Perfusion Diagnostics (1) · Air Force Military Medical University, China (1) · Albert Einstein College of Medicine (1) · Boston Children's Hospital (1) · Central Hospital, Nancy, France (1) · China Medical University Hospital (1) · Chinese University of Hong Kong (1) · Christian Schulze (1)
United States (9) · France (7) · Germany (7) · China (5) · Russia (4) · Belgium (3) · Canada (3) · Czechia (2) · Hungary (2) · Italy (2) · Switzerland (2) · Thailand (2) · United Kingdom (2) · Australia (1) · Austria (1)
Alan Jones, MD (1) · Aleksandr Eremenko, MD (1) · Alma R Marroquin-Escamilla, MD (1) · Bernard Allaouchiche, Prof. (1) · Camille Jeanne-Leroyer, PharmD (1) · Christian Bode, PD Dr. (1) · Christian Schulze, Prof. (1) · Consuelo Mancias-Guerra, MD (1) · Daren Heyland, MD (1) · Denis Protsenko, MD, PHD (1) · El Mehdi Siaghy (1) · Ferdinando Raimondi, Director (1) · Fernando Sanchez Moran (1)
PMID 10470572, PMID 10890632, PMID 11395904, PMID 15276536, PMID 16497588, PMID 16855261, PMID 17638928, PMID 18090355, PMID 18429658, PMID 18434884, PMID 18620598, PMID 18702960, PMID 19531784, PMID 20413034, PMID 21572328, PMID 21918497, PMID 22411933, PMID 22704255, PMID 22751621, PMID 22891167, PMID 23352391, PMID 23519193, PMID 23544148, PMID 23594003, PMID 23725873, PMID 23888228, PMID 23899564, PMID 24232462, PMID 24312305, PMID 24401721, PMID 24777037, PMID 24803474, PMID 24811308, PMID 25242124, PMID 25590523, PMID 25765778, PMID 25814048, PMID 26051981, PMID 26258150, PMID 26621809, PMID 26945160, PMID 26975736, PMID 27288382, PMID 27288610, PMID 27406647, PMID 27836935, PMID 27873291, PMID 28101605, PMID 28127437, PMID 28343448
R01GM104481 (1), UH3HL125119 (1)