51 completed, 17 unknown, 6 recruiting, 4 terminated. 44 Not applicable, 15 Phase 2, 10 Phase 3, 7 Phase 4, 6 Phase 1.
Follow Functional Constipation: new trials by email Literature Review of Functional Constipation trials Research Report on Functional Constipation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Core-Based Movement and Nutritional Counselling for Stress and Metabolic Outcomes in Overweight Women With Functional Constipation Guideline-Based Nutritional Counselling, Core-Based Movement Exercise Program - Functional Constipation | Not applicable | Recruiting | Cairo University | 60 | 2026-10-04 | 2026-10-06 |
| Probiotics for Constipation Relief in Adults Probiotic, Maltodextrin, High-activity probiotic group - Functional Constipation | Not applicable | Not yet recruiting | Wecare Probiotics Co., Ltd. | 105 | 2026-06-10 | 2026-06-09 |
| Co-supplementation With Bifidobacterium Longum W11 and Colopectin for Maintenance Therapy in Children With Functional Constipation Bifidobacterium longum W11 (Bowell®) + Colopectin (Colopectin®), Placebo - Functional Constipation | Not applicable | Not yet recruiting | Liaquat University of Medical & Health Sciences | 100 | 2026-04-20 | 2026-04-17 |
| The Effect of Pelvic Floor Muscle Training in Functional Constipation Lifestyle change training, Diaphragmatic Breathing Exercise, Pelvic Floor Muscle Training - Pelvic Floor, Functional Constipation | Not applicable | Active not recruiting | Selin Koşan | 28 | 2025-12-22 | 2026-05-29 |
| BioAmicus Complete for Functional Gastrointestinal Symptoms in Infants Aged 0 to 24 Months BioAmicus Complete, Usual Care (No Probiotic) - Infantile Colic, Gastroesophageal Reflux (GER) | Not applicable | Recruiting | Haiphong University of Medicine and Pharmacy | 110 | 2025-09-05 | 2026-01-29 |
| A Study of Herbal Supplements in Cancer Survivors With Constipation MZRW - Constipation, Cancer | Not applicable | Recruiting | Memorial Sloan Kettering Cancer Center | 70 | 2025-07-15 | 2026-05-22 |
| A Study to Assess the Effect of the Bio-K+ Probiotic Capsules (VL-BK-02) in Adults With Functional Constipation VL-BK-02 (25 billion CFU/Capsule), Placebo (Microcrystalline Cellulose - 375 mg/capsule) - Functional Constipation | Not applicable | Completed | Vedic Lifesciences Pvt. Ltd. | 168 | 2025-01-25 | 2026-03-19 |
| NutriPlant - Opportunities for Increasing Consumption of Local Fruits and Vegetables Psyllium, Sauerkraut, Fresh apples - Functional Constipation, Irritable Bowel Syndrome | Not applicable | Not yet recruiting | Institute of Nutrition, Slovenia (Nutris) | 120 | 2025-01-20 | 2025-01-21 |
| A Single Arm Pilot Study of the Chinese Herbal Medicine Formula (SCD-2101) for the Functional Constipation in the Elderly SCD-2101 - Functional Constipation | Not applicable | Unknown | Hong Kong Baptist University | 14 | 2024-08-01 | 2024-08-20 |
| The Efficacy and Palatability of Developed Polyethylene Glycol-based Formula for Children With Functional Constipation Local PEG4000, Commercial PEG4000 - Functional Constipation | Not applicable | Recruiting | Chulalongkorn University | 52 | 2024-05-03 | 2026-04-02 |
| Efficacy and Safety Evaluation of Prebiotics Combined With Quadruple Probiotics in Improving Functional Constipation. Take prebiotics and probiotics, lifestyle guidance - Functional Constipation | Not applicable | Unknown | The First Affiliated Hospital of Xiamen University | 60 | 2024-05-01 | 2024-05-01 |
| Comparison of Efficacy & Tolerability Of PEG 4000 Versus PEG 3350+ Electrolytes for Pediatric Fecal Disimpaction Administration of Polyethylene Glycol (PEG) 4000 as per treatment allocation to participants, Administration of Polyethylene Glycol (PEG) 3350 + Electrolyte as per treatment allocation to participants - Functional Constipation, Fecal Impaction | Phase 4 | Unknown | Institute of Medical Sciences and SUM Hospital | 100 | 2024-04-15 | 2024-04-12 |
| Abdominal Massage and Kegel Exercises on Constipation and Quality of Life in Female Students Abdominal massage group, Kegel Exercises group, Both abdominal massage and kegel exercises to gether - Functional Constipation, Constipation | Not applicable | Unknown | Ondokuz Mayıs University | 140 | 2024-03-15 | 2024-03-12 |
| The Efficacy of a Probiotic for Functional Constipation (FC) Probiotic, Placebo - Functional Constipation | Not applicable | Completed | The Archer-Daniels-Midland Company | 55 | 2023-10-19 | 2025-04-09 |
| Visceral Osteopathy in Functional Constipation Osteopathic manual therapy, conservative treatment - Functional Constipation | Not applicable | Completed | Pamukkale University | 27 | 2023-10-01 | 2026-05-29 |
| Effect of Therapeutic Touch on Functional Constipation in Infants and Young Children Therapeutic Touch - Functional Constipation, Therapeutic Touch | Not applicable | Completed | Burdur Mehmet Akif Ersoy University | 60 | 2023-05-03 | 2025-01-01 |
| A Study to Assess Adverse Events and Change in Disease Activity in Pediatric Participants (Age 6 Months to <2 Years) With Functional Constipation Who Are Treated With Linaclotide Linaclotide, Placebo - Functional Constipation | Phase 2 | Completed | AbbVie | 19 | 2023-04-27 | 2026-01-06 |
| Congrong Runtong Oral Liquid in the Treatment of Functional Constipation (Yang-deficiency Type) Congrong Runtong oral liquid, Placental Congrong Runtong oral liquid - Functional Constipation | Phase 2 | Completed | Beijing Hospital of Traditional Chinese Medicine | 180 | 2023-03-29 | 2024-10-28 |
| Study for the Management of Chronic and Functional Constipation Through the Intake of Probiotics and Prebiotics Probiotic, Prebiotic, Probiotic + Prebiotic - Functional Constipation | Not applicable | Completed | Centros de Investigación de Nutrición y Salud | 80 | 2023-03-03 | 2024-04-24 |
| Effect of MiniGo As Add-on to Oral Laxatives for Children with Constipation and Fecal Incontinence Polyethylene Glycols, Low volume trans anal irrigation - Functional Constipation, Fecal Incontinence in Children | Not applicable | Completed | University of Aarhus | 50 | 2022-11-01 | 2024-11-15 |
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Constipation (19) · Gastrointestinal Diseases (5) · Irritable Bowel Syndrome (3) · Colic (2) · Abdominal Pain (1) · Autism Spectrum Disorder (1) · Colonic Diseases (1) · Developmental Disabilities (1) · Digestive System Diseases (1) · Disease (1) · Dysbiosis (1) · Dyspepsia (1) · Ehlers-Danlos syndrome type 3 (1) · Encopresis (1) · Fecal Impaction (1)
Pathological Conditions, Signs and Symptoms (23) · Signs and Symptoms (20) · Signs and Symptoms, Digestive (20) · Digestive System Diseases (11) · Gastrointestinal Diseases (7) · Intestinal Diseases (6) · Behavior (3) · Colonic Diseases (3) · Colonic Diseases, Functional (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Infant, Newborn, Diseases (2) · Pathologic Processes (2) · Behavioral Symptoms (1) · Child Development Disorders, Pervasive (1) · Congenital Abnormalities (1)
Probiotics (5) · maltodextrin (5) · linaclotide (3) · 12,13-dihydro-N-methyl-6,11,13-trioxo-5H-benzo(4,5)cyclohepta(1,2-b)naphthalen-5,12-imine (2) · Acupuncture Therapy (2) · Diet Therapy (2) · Polyethylene Glycols (2) · Standard of Care (2) · dai-kenchu-to (2) · microcrystalline cellulose (2) · mosapride (2) · polydextrose (2) · prucalopride (2) · (1-6)-alpha-glucomannan (1) · Behavior Therapy (1)
AbbVie (3) · Chonbuk National University Hospital (3) · Hong Kong Baptist University (3) · Medical University of Warsaw (3) · Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis (2) · Cairo University (2) · Danisco (2) · Huazhong University of Science and Technology (2) · KGK Science Inc. (2) · Syral (2) · Tsumura USA (2) · AB Biotics, SA (1) · AIDP, Inc. (1) · Allergan (1) · Anji Pharma (1)
United States (16) · China (13) · Italy (7) · Netherlands (6) · Canada (5) · France (4) · Poland (4) · South Korea (4) · Turkey (Türkiye) (4) · Egypt (3) · Germany (3) · Israel (3) · United Kingdom (3) · Belgium (2) · Bulgaria (2)
Michael Camilleri, MD (3) · Tetyana Pelipyagina, MD (2) · Zhao Xiang Bian, MD, Ph. D (2) · Agnieszka Wegner, M.D. (1) · Alice C Huang, MD (1) · Anders F Mellgren, MD, PhD (1) · Ann Ming Yeh, MD (1) · Anna Muslin (1) · Annamaria Staiano, Prof. (1) · Ara Festekjian, MD (1) · Caterina Strisciuglio, Prof. (1) · Ching Lam, MBChB MRCP (1) · Clara Belzer, PhD (1)
PMID 16036506, PMID 16678553, PMID 10395609, PMID 10395611, PMID 10620476, PMID 10636972, PMID 11321024, PMID 11321031, PMID 11535863, PMID 12088518, PMID 12219064, PMID 12492746, PMID 12583961, PMID 14599043, PMID 14690361, PMID 14993586, PMID 15521853, PMID 15572881, PMID 15638753, PMID 15860162, PMID 16000928, PMID 16498248, PMID 16678561, PMID 16678566, PMID 16771074, PMID 16819379, PMID 17032205, PMID 17110723, PMID 17329047, PMID 17464377, PMID 17497967, PMID 17711612, PMID 17727672, PMID 18193118, PMID 18608562, PMID 18713795, PMID 19524752, PMID 19685935, PMID 19747148, PMID 19941629, PMID 19948614, PMID 20006033, PMID 20180788, PMID 20197661, PMID 20497775, PMID 21205879, PMID 21320737, PMID 21382575, PMID 21617937, PMID 21724488
2019 (3), UL1RR024150 (1)