28 completed, 12 unknown, 4 withdrawn, 3 terminated. 21 Not applicable, 15 Phase 2, 3 Phase 1, 3 Phase 4, 2 Phase 3.
Follow Cytokine Storm: new trials by email Literature Review of Cytokine Storm trials Research Report on Cytokine Storm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Jafron Cytokine Adsorber During Pediatric Open-Heart Surgeries Hemoadsorption - Cardiac Surgery Recovery, Inflammation | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire Vaudois | 20 | 2026-03-01 | 2026-02-10 |
| MRG-001 as an Immunoregulatory and Regenerative Therapy for ARDS Patients MRG-001 (Low-dose), MRG-001 (High-dose), Placebo - Acute Respiratory Distress Syndrome, Respiratory Failure | Phase 2 | Unknown | MedRegen LLC | 60 | 2024-12-01 | 2024-08-23 |
| Clinical Outcomes and Inflammatory Responses in Viral vs. Bacterial Sepsis observation - Sepsis, Sepsis Bacterial | Unknown | Sichuan Provincial People's Hospital | 300 | 2024-04-02 | 2024-07-09 | |
| Anakinra in Dengue With Hyperinflammation ( AnaDen ) Placebo, Anakinra - Dengue, Dengue With Warning Signs | Phase 2 | Active not recruiting | Oxford University Clinical Research Unit, Vietnam | 160 | 2023-01-02 | 2026-01-06 |
| Interleukin-34 in Stage I and II Periodontitis Non-Surgical periodontal therapy - Cytokine Storm | Not applicable | Completed | Ain Shams University | 45 | 2023-01-01 | 2023-09-28 |
| CORONA: A Study Using DeltaRex-G Gene Therapy for Symptomatic COVID-19 DeltaRex-G - COVID-19, Cytokine Storm | Phase 1 / Phase 2 | Withdrawn | Aveni Foundation | 2022-12-12 | 2025-02-24 | |
| Cytokine Guided Risk Stratification and Treatment in Pediatric Hemophagocytic Lymphohistiocytosis Dexamethasone, Etoposide, Ruxolitinib - Hemophagocytic Lymphohistiocytoses, Cytokine Storm | Phase 4 | Unknown | The Children's Hospital of Zhejiang University School of Medicine | 400 | 2022-09-01 | 2022-10-06 |
| Relationship Between Oral Findings and Salivary Factors in Sars-Cov-2 Patients ELISA test for Cytokines - Decay, Dental, Missing Teeth | Not applicable | Completed | Ege University | 320 | 2022-03-01 | 2023-08-15 |
| CLinical Efficacy of Hemoperfusion With a Cytokine Adsorber in Norepinephrine-Resistant SEptic Shock HA-330 Disposable Hemoperfusion Cartridge (Jafron, China) - Septic Shock, Cytokine Storm | Not applicable | Unknown | Mahidol University | 200 | 2021-12-15 | 2021-11-29 |
| Anakinra, COVID-19, Cytokine Storm Anakinra, 0.9% Saline - Covid19, Cytokine Storm | Phase 2 | Withdrawn | Weill Medical College of Cornell University | 2021-12-01 | 2022-01-25 | |
| Exploratory Regimen of Basiliximab for Treatment of Pulmonary Cytokine Storm in SARS-CoV-2 Hospitalized Adult Patients Basiliximab Injection, Placebo - SARS-CoV-2 Acute Respiratory Disease, SARS-CoV2 Infection | Phase 2 | Unknown | Fort Worth Clinical Sciences Working Group | 300 | 2021-10-15 | 2021-08-19 |
| Non-invasive Nervus Vagus Stimulation in Patients With COVID-19 and ARDS AuriStim - COVID-19, ARDS | Not applicable | Unknown | Vienna Hospital Association | 20 | 2021-07-15 | 2022-10-25 |
| UNITE Study (UMN-SW) for COVID-19 Splenic Ultrasound - Covid19, Cytokine Storm | Not applicable | Completed | University of Minnesota | 58 | 2021-04-29 | 2024-05-03 |
| Menstrual Blood Stem Cells in Severe Covid-19 Allogeneic human menstrual blood stem cells secretome, Intravenous saline injection - Covid19, Cytokine Storm | Phase 1 / Phase 2 | Completed | Avicenna Research Institute | 29 | 2021-04-17 | 2021-09-02 |
| Prospective Study for the Application of Cytosorb® in Critically Ill Patients Cytosorb therapy - Rhabdomyolysis, Acute Liver Injury | Not applicable | Completed | Ludwig-Maximilians - University of Munich | 57 | 2021-03-01 | 2024-02-22 |
| Intercellular Adhesion Molecule-1 and TNF-α in Patients With COVID-19 COVID-19, Cytokine Storm | Completed | Benha University | 100 | 2021-02-01 | 2022-06-14 | |
| High-Dose Corticosteroid or Tocilizumab for Clinical Worsening of COVID-19 Methylprednisolone, Tocilizumab - COVID-19 Virus Infection, Cytokine Storm | Phase 4 | Withdrawn | Marmara University | 2021-02-01 | 2021-11-24 | |
| UNITE Study (UMN-GE) for COVID-19 Splenic ultrasound - Covid19, Cytokine Storm | Not applicable | Completed | University of Minnesota | 30 | 2021-01-14 | 2024-05-03 |
| Asses the Anti-inflammatory Effects of Short Term Copaxone Therapy on Patients the Acute Decompensated Heart Failure Copaxone, guideline directed medical therapy (GDMT) - Acute Decompensated Heart Failure, Cytokine Storm | Phase 2 | Completed | Hadassah Medical Organization | 14 | 2021-01-04 | 2023-08-22 |
| Esmolol in Sepsis Management:Evaluating Immunomodulatory Effects and Impact on Patient Outcomes esmolol - Sepsis, Lymphocyte Disorder T | Phase 2 | Completed | Lin Chen | 150 | 2021-01-01 | 2024-05-29 |
Showing 20 of 52. Sign in to see all of them.
Cytokine Release Syndrome (52) · COVID-19 (30) · Coronavirus Infections (8) · Respiratory Distress Syndrome (7) · Inflammation (5) · Sepsis (5) · Respiratory Insufficiency (4) · Shock, Septic (4) · Severe Acute Respiratory Syndrome (3) · Burns (2) · Heart Arrest (2) · Heart Failure (2) · Hypoxia (2) · Multiple Organ Failure (2) · Anodontia (1)
Pathologic Processes (52) · Pathological Conditions, Signs and Symptoms (52) · Systemic Inflammatory Response Syndrome (52) · Shock (51) · Inflammation (47) · Infections (39) · Lung Diseases (34) · Respiratory Tract Diseases (33) · Virus Diseases (33) · RNA Virus Infections (32) · Coronaviridae Infections (31) · Nidovirales Infections (31) · Respiratory Tract Infections (31) · Pneumonia (30) · Pneumonia, Viral (30)
tocilizumab (4) · Adrenal Cortex Hormones (3) · Interleukin 1 Receptor Antagonist Protein (3) · Methylprednisolone (2) · Saline Solution (2) · Standard of Care (2) · Azithromycin (1) · Basiliximab (1) · Calcifediol (1) · Cholecalciferol (1) · Continuous Renal Replacement Therapy (1) · Dexamethasone (1) · Dexmedetomidine (1) · Doxycycline (1) · Etoposide (1)
Ain Shams University (4) · Applied Science Private University (2) · Dr. Alexander Supady (2) · University of Minnesota (2) · AB Biotek (1) · AURA Paris (1) · Aretaieion University Hospital (1) · Aveni Foundation (1) · Avicenna Research Institute (1) · Benha University (1) · Centre Hospitalier Universitaire Vaudois (1) · Direct Biologics, LLC (1) · Ege University (1) · Federal University of São Paulo (1) · Fort Worth Clinical Sciences Working Group (1)
United States (8) · Egypt (5) · Germany (5) · China (4) · Spain (3) · Austria (2) · Jordan (2) · Mexico (2) · Brazil (1) · France (1) · Greece (1) · Hungary (1) · Indonesia (1) · Iran (1) · Israel (1)
Neven Sarhan, PhD (3) · Alexander Supady, Dr., MPH (2) · Mahmoud S Abu-Samak, PhD (2) · Agung Putra, Assoc.Prof (1) · Alexander Zoufaly, MD (1) · Ali Dehghan-Manshadi, MD (1) · Anders Kjellberg, MD (1) · Andrew Olson, M.D. (1) · Antoine Schneider, MD-PhD (1) · Arthur M Feldman, MD, PhD (1) · Bill Arana (1) · Cem Peskersoy (1) · Dana A Bader, MSc (1) · Daniel Azamar-Llamas, MD (1)
PMID 10415784, PMID 12563677, PMID 14719037, PMID 15663512, PMID 16213065, PMID 16368644, PMID 17181919, PMID 17344507, PMID 17487675, PMID 1750226, PMID 17921398, PMID 18097874, PMID 18550812, PMID 19275682, PMID 19397687, PMID 19453649, PMID 19998041, PMID 21118369, PMID 21131395, PMID 21445287, PMID 22028728, PMID 22381456, PMID 22545014, PMID 22731679, PMID 22907572, PMID 24348219, PMID 24804272, PMID 25278144, PMID 26031679, PMID 26817502, PMID 26867177, PMID 27103044, PMID 28584818, PMID 30473697, PMID 30935016, PMID 31060383, PMID 31544248, PMID 31933547, PMID 31986264, PMID 32035018, PMID 32089354, PMID 32113509, PMID 32125455, PMID 32140081, PMID 32159775, PMID 32192578, PMID 32203186, PMID 32223047, PMID 32234467, PMID 32257537