7 completed, 3 terminated, 3 withdrawn, 1 unknown. 14 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 14 | Completed 7, Terminated 3, Withdrawn 3, Unknown 1 |
Follow Clostridium Difficile Infection: new trials by email Literature Review of Clostridium Difficile Infection trials Research Report on Clostridium Difficile Infection
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oral Vancomycin for Secondary Prophylaxis of Clostridium Difficile Infection (CDI) Oral Vancomycin, Placebo - Clostridium Difficile Infection, Clostridium Difficile Infection Recurrence | Phase 4 | Terminated | University of South Florida | 26 | 2019-09-01 | 2023-04-21 |
| Fecal Microbiota Transplant Fecal Microbiota Transplant - Clostridium Difficile Infection | Phase 4 | Completed | Methodist Health System | 24 | 2018-06-05 | 2026-03-24 |
| Fidaxomicin Versus Standard of Care Therapy in Solid Organ Transplant Recipients With Clostridium Difficile Infection fidaxomicin - Clostridium Difficile Infection, Solid Organ Transplant | Phase 4 | Withdrawn | University of Colorado, Denver | 2018-06-01 | 2018-08-29 | |
| Oral Vancomycin to Prevent Recurrent C Difficile Infection With Antibiotics Oral Vancomycin - Clostridium Difficile Infection | Phase 4 | Completed | University of Nevada, Reno | 104 | 2018-03-08 | 2023-11-28 |
| Use of Bismuth Subsalicylate in Clostridium Difficile Colitis Bismuth Subsalicylate, standard antibiotic therapy - Clostridium Difficile Infection | Phase 4 | Withdrawn | Bassett Healthcare | 2018-03-01 | 2018-07-19 | |
| TOX NEG Trial: Clostridium Difficile Diagnosis and Treatment Oral Vancomycin, Placebo, Toxin enzyme immunoassay - Clostridium Difficile Infection, Diarrhea | Phase 4 | Completed | Washington University School of Medicine | 15 | 2017-12-29 | 2021-07-26 |
| Oral Vancomycin for Preventing Clostridium Difficile Recurrence Oral Vancomycin, Placebo - Clostridium Difficile Infection | Phase 4 | Terminated | Rochester General Hospital | 65 | 2017-06-08 | 2021-04-26 |
| Screening to Prophylax Against Clostridium Difficile Infection - Vancomycin, Placebo - Clostridium Difficile Infection | Phase 4 | Completed | Corewell Health East | 1294 | 2016-12-19 | 2024-08-13 |
| Oral Vancomyin for Primary Clostridium Difficile Infection Prophylaxis in Patients Receiving High-Risk Antibiotics Vancomycin Oral - Clostridium Difficile Infection, Prophylaxis | Phase 4 | Completed | St. Luke's Hospital, Chesterfield, Missouri | 51 | 2016-11-01 | 2017-12-27 |
| Vancomycin Prophylaxis in Recurrent Clostridium Difficile Infection Vancomycin, fruit juice/placebo - Clostridium Difficile Infection | Phase 4 | Unknown | Corewell Health West | 140 | 2014-08-01 | 2014-09-11 |
| Study of Bio-K+® in the Reduction of the Risk of Clostridium Difficile Infection and Antibiotic Associated Diarrhea Bio K+® 2 capsules orally (or via nasogastric tube), Placebo - Clostridium Difficile Infection, Antibiotic Associated Diarrhea | Phase 4 | Terminated | Bio-K Plus International Inc. | 60 | 2013-11-01 | 2022-07-22 |
| Rifaximin for Preventing Relapse of Clostridium Associated Diarrhoea Rifaximin, Placebo - Clostridium Difficile Infection | Phase 4 | Completed | University of Nottingham | 151 | 2012-12-01 | 2021-10-14 |
| Study to Assess Inhibition of Spore Production in Patients With C. Difficile Infections: Fidaxomicin Versus Vancomycin Vancomycin, Fidaxomicin - Clostridium Difficile Infection | Phase 4 | Completed | Hartford Hospital | 34 | 2012-10-17 | 2017-06-28 |
| Fidaxomicin to Prevent Clostridium Difficile Colonization Fidaxomicin, Placebo - Clostridium Difficile Infection | Phase 4 | Withdrawn | Washington University School of Medicine | 2012-09-01 | 2014-05-28 |
Clostridium Infections (14) · Diarrhea (2) · Infections (1)
Bacterial Infections (14) · Bacterial Infections and Mycoses (14) · Gram-Positive Bacterial Infections (14) · Infections (13) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Signs and Symptoms, Digestive (2)
Vancomycin (8) · Fidaxomicin (3) · Drug Evaluation (1) · Fecal Microbiota Transplantation (1) · Fruit and Vegetable Juices (1) · Rifaximin (1) · bismuth subsalicylate (1)
Washington University School of Medicine (2) · Bassett Healthcare (1) · Bio-K Plus International Inc. (1) · Corewell Health East (1) · Corewell Health West (1) · Hartford Hospital (1) · Methodist Health System (1) · Rochester General Hospital (1) · St. Luke's Hospital, Chesterfield, Missouri (1) · University of Colorado, Denver (1) · University of Nevada, Reno (1) · University of Nottingham (1) · University of South Florida (1)
United States (10) · Canada (1) · United Kingdom (1)
Abdulhadi Quadri, MD (1) · Aida Jawhari, MD (1) · Andrew Maternowski, MD (1) · Erik Dubberke, MD, MSPH (1) · Kelly E Schoeppler, PharmD (1) · Lauren Zion, PharmD (1) · Maryrose R Laguio-Vila, MD (1) · Matthew Sims, MD PhD (1) · Mikhael Laskine, MD (1) · Mindy Sampson, DO (1) · Muhammad Memon, MD (1) · Ryan E Medas, PharmD (1) · Serge Carriere, MD (1)
PMID 26592763, PMID 27558181, PMID 30254135, PMID 33441409
U54CK000162 (1)