Most Influential GUT Papers
Gut is a leading international journal in gastroenterology and hepatology and has an established reputation for publishing first class clinical research of the alimentary tract, the liver, biliary tree and pancreas. Paper Digest Team analyze all papers published on GUT in the past years, and presents the 10 most influential papers for each year (based on when the paper became available online). This ranking list is automatically constructed based upon citations from both research papers and granted patents, and will be frequently updated to reflect the most recent changes. To find the most influential papers from other conferences/journals, visit Best Paper Digest page. Note: the most influential papers may or may not include the papers that won the best paper awards. (Last updated on: 2021-05-23)
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TABLE 1: Most Influential GUT Papers
Year | Rank | Paper | Author(s) |
---|---|---|---|
2020 | 1 | Epidemiological, Clinical and Virological Characteristics of 74 Cases of Coronavirus-infected Disease 2019 (COVID-19) with Gastrointestinal Symptoms IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The SARS-CoV-2-infected disease (COVID-19) outbreak is a major threat to human beings. Previous studies mainly focused on Wuhan and typical symptoms. We analysed 74 confirmed … |
XI JIN et. al. |
2020 | 2 | Guidelines on The Management of Ascites in Cirrhosis IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The British Society of Gastroenterology in collaboration with British Association for the Study of the Liver has prepared this document. The aim of this guideline is to review and … |
GURUPRASAD P AITHAL et. al. |
2020 | 3 | Gastrointestinal Symptoms of 95 Cases with SARS-CoV-2 Infection IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: To study the GI symptoms in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected patients. We analysed epidemiological, demographic, clinical and laboratory data … |
LU LIN et. al. |
2020 | 4 | Diarrhoea May Be Underestimated: A Missing Link In 2019 Novel Coronavirus IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details |
WEICHENG LIANG et. al. |
2020 | 5 | Digestive System Is A Potential Route of COVID-19: An Analysis of Single-cell Coexpression Pattern of Key Proteins in Viral Entry Process IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Objective Since December 2019, a newly identified coronavirus (severe acute respiratory syndrome coronavirus (SARS-CoV-2)) has caused outbreaks of pneumonia in Wuhan, China. … |
HAO ZHANG et. al. |
2020 | 6 | Practice of Endoscopy During COVID-19 Pandemic: Position Statements of The Asian Pacific Society for Digestive Endoscopy (APSDE-COVID Statements) IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Coronavirus-19 (COVID-19) caused by SARS-CoV-2 has become a global pandemic. Risk of transmission may occur during endoscopy and the goal is to prevent infection among healthcare … |
PHILIP WAI YAN CHIU et. al. |
2020 | 7 | SARS-CoV-2 Induced Diarrhoea As Onset Symptom In Patient With COVID-19 IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details |
Y SONG et. al. |
2020 | 8 | Outcomes of COVID-19 in 79 Patients with IBD in Italy: An IG-IBD Study IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: COVID-19 has rapidly become a major health emergency worldwide. Patients with IBD are at increased risk of infection, especially when they have active disease and are taking … |
CRISTINA BEZZIO et. al. |
2020 | 9 | COVID-19 and Immunomodulation in IBD IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The current coronavirus pandemic is an ongoing global health crisis due to COVID-19, caused by severe acute respiratory syndrome coronavirus 2. Although COVID-19 leads to little … |
Markus F Neurath; |
2020 | 10 | British Society of Gastroenterology Guidance for Management of Inflammatory Bowel Disease During The COVID-19 Pandemic IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The COVID-19 pandemic is putting unprecedented pressures on healthcare systems globally. Early insights have been made possible by rapid sharing of data from China and Italy. In … |
NICHOLAS A KENNEDY et. al. |
2019 | 1 | European Association for The Study of The Liver IF:8 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: We cover key sessions on hepatitis B, C, and D virus infections, hepatocellular carcinoma, nonalcoholic steatohepatitis, acute hepatic porphyria, and liver growth in polycystic … |
Walter Alexander; |
2019 | 2 | British Society of Gastroenterology Consensus Guidelines on The Management of Inflammatory Bowel Disease in Adults IF:5 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Ulcerative colitis and Crohn’s disease are the principal forms of inflammatory bowel disease. Both represent chronic inflammation of the gastrointestinal tract, which displays … |
CHRISTOPHER ANDREW LAMB et. al. |
2019 | 3 | Real-time Automatic Detection System Increases Colonoscopic Polyp And Adenoma Detection Rates: A Prospective Randomised Controlled Study IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The effect of colonoscopy on colorectal cancer mortality is limited by several factors, among them a certain miss rate, leading to limited adenoma detection rates (ADRs). We … |
PU WANG et. al. |
2019 | 4 | Role Of The Microbiome In Human Development IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The host-microbiome supraorganism appears to have coevolved and the unperturbed microbial component of the dyad renders host health sustainable. This coevolution has likely shaped … |
Maria Gloria Dominguez-Bello; Filipa Godoy-Vitorino; Rob Knight; Martin J Blaser; |
2019 | 5 | Increasing Incidence of Colorectal Cancer in Young Adults in Europe Over The Last 25 Years IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The incidence of colorectal cancer (CRC) declines among subjects aged 50 years and above. An opposite trend appears among younger adults. In Europe, data on CRC incidence among … |
FANNY ER VUIK et. al. |
2019 | 6 | Effects of Dietary Fat on Gut Microbiota and Faecal Metabolites, and Their Relationship with Cardiometabolic Risk Factors: A 6-month Randomised Controlled-feeding Trial IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: To investigate whether diets differing in fat content alter the gut microbiota and faecal metabolomic profiles, and to determine their relationship with cardiometabolic risk … |
YI WAN et. al. |
2019 | 7 | Leaky Gut: Mechanisms, Measurement and Clinical Implications in Humans IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The objectives of this review on ‘leaky gut’ for clinicians are to discuss the components of the intestinal barrier, the diverse measurements of intestinal permeability, their … |
Michael Camilleri; |
2019 | 8 | International Consensus Conference on Stool Banking for Faecal Microbiota Transplantation in Clinical Practice IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Although faecal microbiota transplantation (FMT) has a well-established role in the treatment of recurrent infection (CDI), its widespread dissemination is limited by several … |
GIOVANNI CAMMAROTA et. al. |
2019 | 9 | Gut Mucosal Virome Alterations in Ulcerative Colitis IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The pathogenesis of UC relates to gut microbiota dysbiosis. We postulate that alterations in the viral community populating the intestinal mucosa play an important role in UC … |
TAO ZUO et. al. |
2019 | 10 | British Society of Gastroenterology Guidelines on The Diagnosis and Management of Patients at Risk of Gastric Adenocarcinoma IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Gastric adenocarcinoma carries a poor prognosis, in part due to the late stage of diagnosis. Risk factors include infection, family history of gastric cancer-in particular, … |
MATTHEW BANKS et. al. |
2018 | 1 | Human Gut Microbiome: Hopes, Threats And Promises IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The microbiome has received increasing attention over the last 15 years. Although gut microbes have been explored for several decades, investigations of the role of microorganisms … |
Patrice D Cani; |
2018 | 2 | Modern Diagnosis Of GERD: The Lyon Consensus IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Clinical history, questionnaire data and response to antisecretory therapy are insufficient to make a conclusive diagnosis of GERD in isolation, but are of value in determining … |
C PRAKASH GYAWALI et. al. |
2018 | 3 | Gut Commensal Parabacteroides Goldsteinii Plays A Predominant Role In The Anti-obesity Effects Of Polysaccharides Isolated From Hirsutella Sinensis IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The medicinal fungus and its anamorph have a long history of use in traditional Chinese medicine for their immunomodulatory properties. Alterations of the gut microbiota have been … |
TSUNG-RU WU et. al. |
2018 | 4 | Gut Microbiome Analysis As A Tool Towards Targeted Non-invasive Biomarkers For Early Hepatocellular Carcinoma IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: To characterise gut microbiome in patients with hepatocellular carcinoma (HCC) and evaluate the potential of microbiome as non-invasive biomarkers for HCC. We collected 486 faecal … |
ZHIGANG REN et. al. |
2018 | 5 | Faecal Microbiota Transplantation Alters Gut Microbiota In Patients With Irritable Bowel Syndrome: Results From A Randomised, Double-blind Placebo-controlled Study IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: IBS is associated with an intestinal dysbiosis and faecal microbiota transplantation (FMT) has been hypothesised to have a positive effect in patients with IBS. We performed a … |
SOFIE INGDAM HALKJÆR et. al. |
2018 | 6 | Major Microbiota Dysbiosis In Severe Obesity: Fate After Bariatric Surgery IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Decreased gut microbial gene richness (MGR) and compositional changes are associated with adverse metabolism in overweight or moderate obesity, but lack characterisation in severe … |
JUDITH ARON-WISNEWSKY et. al. |
2018 | 7 | The Use Of Faecal Microbiota Transplant As Treatment For Recurrent Or Refractory Clostridium Difficile Infection And Other Potential Indications: Joint British Society Of Gastroenterology (BSG) And Healthcare Infection Society (HIS) Guidelines IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Interest in the therapeutic potential of faecal microbiota transplant (FMT) has been increasing globally in recent years, particularly as a result of randomised studies in which … |
BENJAMIN H MULLISH et. al. |
2018 | 8 | Deep Learning Radiomics Of Shear Wave Elastography Significantly Improved Diagnostic Performance For Assessing Liver Fibrosis In Chronic Hepatitis B: A Prospective Multicentre Study IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: We aimed to evaluate the performance of the newly developed deep learning Radiomics of elastography (DLRE) for assessing liver fibrosis stages. DLRE adopts the radiomic strategy … |
KUN WANG et. al. |
2018 | 9 | Stromal Biology And Therapy In Pancreatic Cancer: Ready For Clinical Translation? IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Pancreatic ductal adenocarcinoma (PDA) is notoriously aggressive and hard to treat. The tumour microenvironment (TME) in PDA is highly dynamic and has been found to promote tumour … |
ALBRECHT NEESSE et. al. |
2018 | 10 | Serial Circulating Tumour DNA Analysis During Multimodality Treatment Of Locally Advanced Rectal Cancer: A Prospective Biomarker Study IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: For patients with locally advanced rectal cancer (LARC), adjuvant chemotherapy selection following surgery remains a major clinical dilemma. Here, we investigated the ability of … |
JEANNE TIE et. al. |
2017 | 1 | European Consensus Conference On Faecal Microbiota Transplantation In Clinical Practice IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Faecal microbiota transplantation (FMT) is an important therapeutic option for infection. Promising findings suggest that FMT may play a role also in the management of other … |
GIOVANNI CAMMAROTA et. al. |
2017 | 2 | Non-alcoholic Fatty Liver Disease And Its Relationship With Cardiovascular Disease And Other Extrahepatic Diseases IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Key physiological functions of the liver, including glucose and lipid metabolism, become disturbed in the setting of non-alcoholic fatty liver disease (NAFLD) and may be … |
Leon A Adams; Quentin M Anstee; Herbert Tilg; Giovanni Targher; |
2017 | 3 | A Microbial Signature For Crohn’s Disease IF:5 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: A decade of microbiome studies has linked IBD to an alteration in the gut microbial community of genetically predisposed subjects. However, existing profiles of gut microbiome … |
VICTORIA PASCAL et. al. |
2017 | 4 | Real-time Differentiation Of Adenomatous And Hyperplastic Diminutive Colorectal Polyps During Analysis Of Unaltered Videos Of Standard Colonoscopy Using A Deep Learning Model IF:5 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: In general, academic but not community endoscopists have demonstrated adequate endoscopic differentiation accuracy to make the ‘resect and discard’ paradigm for diminutive … |
MICHAEL F BYRNE et. al. |
2017 | 5 | Acute-on-chronic Liver Failure: An Update IF:5 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Acute-on-chronic liver failure (ACLF) is a syndrome characterised by acute decompensation of chronic liver disease associated with organ failures and high short-term mortality. … |
Ruben Hernaez; Elsa Solà; Richard Moreau; Pere Ginès; |
2017 | 6 | Cancer Risk and Survival in Path_MMR Carriers By Gene and Gender Up to 75 Years of Age: A Report from The Prospective Lynch Syndrome Database IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Most patients with gene variants (Lynch syndrome (LS)) now survive both their first and subsequent cancers, resulting in a growing number of older patients with LS for whom … |
PÅL MØLLER et. al. |
2017 | 7 | Recovery of Ethanol-induced Akkermansia Muciniphila Depletion Ameliorates Alcoholic Liver Disease IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Alcoholic liver disease (ALD) is a global health problem with limited therapeutic options. Intestinal barrier integrity and the microbiota modulate susceptibility to ALD. , a … |
CHRISTOPH GRANDER et. al. |
2017 | 8 | Drug-induced Liver Injury: Recent Advances In Diagnosis And Risk Assessment IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Idiosyncratic drug-induced liver injury (IDILI) is a rare but potentially severe adverse drug reaction that should be considered in patients who develop laboratory criteria for … |
GERD A KULLAK-UBLICK et. al. |
2017 | 9 | Adherent-invasive Escherichia Coli In Inflammatory Bowel Disease IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Intestinal microbiome dysbiosis has been consistently described in patients with IBD. In the last decades, , and the adherent-invasive (AIEC) pathotype in particular, has been … |
CAROLINA PALMELA et. al. |
2017 | 10 | Long-term Proton Pump Inhibitors and Risk of Gastric Cancer Development After Treatment for Helicobacter Pylori: A Population-based Study IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Objective Proton pump inhibitors (PPIs) is associated with worsening of gastric atrophy, particularly in Helicobacter pylori (HP)-infected subjects. We determined the association … |
KA SHING CHEUNG et. al. |
2016 | 1 | Global Patterns And Trends In Colorectal Cancer Incidence And Mortality IF:8 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The global burden of colorectal cancer (CRC) is expected to increase by 60% to more than 2.2 million new cases and 1.1 million deaths by 2030. In this study, we aim to describe … |
MELINA ARNOLD et. al. |
2016 | 2 | Fungal Microbiota Dysbiosis In IBD IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The bacterial intestinal microbiota plays major roles in human physiology and IBDs. Although some data suggest a role of the fungal microbiota in IBD pathogenesis, the available … |
HARRY SOKOL et. al. |
2016 | 3 | The Safety Of Vedolizumab For Ulcerative Colitis And Crohn’s Disease IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Vedolizumab is a gut-selective antibody to α β integrin for the treatment of ulcerative colitis (UC) and Crohn’s disease (CD). We report an integrated summary of the safety of … |
JEAN-FRÉDÉRIC COLOMBEL et. al. |
2016 | 4 | Interplay Of Host Genetics And Gut Microbiota Underlying The Onset And Clinical Presentation Of Inflammatory Bowel Disease IF:5 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Patients with IBD display substantial heterogeneity in clinical characteristics. We hypothesise that individual differences in the complex interaction of the host genome and the … |
FLORIS IMHANN et. al. |
2016 | 5 | Tumour-associated And Non-tumour-associated Microbiota In Colorectal Cancer IF:5 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: A signature that unifies the colorectal cancer (CRC) microbiota across multiple studies has not been identified. In addition to methodological variance, heterogeneity may be … |
BURKHARDT FLEMER et. al. |
2016 | 6 | Human Oral Microbiome And Prospective Risk For Pancreatic Cancer: A Population-based Nested Case-control Study IF:5 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: A history of periodontal disease and the presence of circulating antibodies to selected oral pathogens have been associated with increased risk of pancreatic cancer; however, … |
XIAOZHOU FAN et. al. |
2016 | 7 | Endoscopy In Patients On Antiplatelet Or Anticoagulant Therapy, Including Direct Oral Anticoagulants: British Society Of Gastroenterology (BSG) And European Society Of Gastrointestinal Endoscopy (ESGE) Guidelines IF:5 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The risk of endoscopy in patients on antithrombotics depends on the risks of procedural haemorrhage versus thrombosis due to discontinuation of therapy. P2Y12 RECEPTOR ANTAGONISTS … |
ANDREW M VEITCH et. al. |
2016 | 8 | Current And Upcoming Pharmacotherapy For Non-alcoholic Fatty Liver Disease IF:5 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Given the high prevalence and rising incidence of non-alcoholic fatty liver disease (NAFLD), the absence of approved therapies is striking. Although the mainstay of treatment of … |
Yaron Rotman; Arun J Sanyal; |
2016 | 9 | Patterns Of PD-L1 Expression And CD8 T Cell Infiltration In Gastric Adenocarcinomas And Associated Immune Stroma IF:5 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Recent data supports a significant role for immune checkpoint inhibitors in the treatment of solid tumours. Here, we evaluate gastric and gastro-oesophageal junction (G/GEJ) … |
ELIZABETH D THOMPSON et. al. |
2016 | 10 | FODMAPs Alter Symptoms And The Metabolome Of Patients With IBS: A Randomised Controlled Trial IF:5 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: To gain mechanistic insights, we compared effects of low fermentable oligosaccharides, disaccharides and monosaccharides and polyols (FODMAP) and high FODMAP diets on symptoms, … |
KEITH MCINTOSH et. al. |
2015 | 1 | The Gut Microbiota And Host Health: A New Clinical Frontier IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Over the last 10-15 years, our understanding of the composition and functions of the human gut microbiota has increased exponentially. To a large extent, this has been due to new … |
JULIAN R MARCHESI et. al. |
2015 | 2 | Akkermansia Muciniphila And Improved Metabolic Health During A Dietary Intervention In Obesity: Relationship With Gut Microbiome Richness And Ecology IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Individuals with obesity and type 2 diabetes differ from lean and healthy individuals in their abundance of certain gut microbial species and microbial gene richness. Abundance of … |
MARIA CARLOTA DAO et. al. |
2015 | 3 | Kyoto Global Consensus Report On Helicobacter Pylori Gastritis IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: To present results of the Kyoto Global Consensus Meeting, which was convened to develop global consensus on (1) classification of chronic gastritis and duodenitis, (2) clinical … |
KENTARO SUGANO et. al. |
2015 | 4 | Colorectal Cancer Screening: A Global Overview Of Existing Programmes IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Colorectal cancer (CRC) ranks third among the most commonly diagnosed cancers worldwide, with wide geographical variation in incidence and mortality across the world. Despite … |
ELINE H SCHREUDERS et. al. |
2015 | 5 | High-level Adherence To A Mediterranean Diet Beneficially Impacts The Gut Microbiota And Associated Metabolome IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Habitual diet plays a major role in shaping the composition of the gut microbiota, and also determines the repertoire of microbial metabolites that can influence the host. The … |
FRANCESCA DE FILIPPIS et. al. |
2015 | 6 | Pathobiology Of Liver Fibrosis: A Translational Success Story IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Reversibility of hepatic fibrosis and cirrhosis following antiviral therapy for hepatitis B or C has advanced the prospect of developing antifibrotic therapies for patients with … |
Youngmin A Lee; Michael C Wallace; Scott L Friedman; |
2015 | 7 | Diagnosis And Management Of Acute Kidney Injury In Patients With Cirrhosis: Revised Consensus Recommendations Of The International Club Of Ascites IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details |
PAOLO ANGELI et. al. |
2015 | 8 | Proton Pump Inhibitors Affect The Gut Microbiome IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Proton pump inhibitors (PPIs) are among the top 10 most widely used drugs in the world. PPI use has been associated with an increased risk of enteric infections, most notably … |
FLORIS IMHANN et. al. |
2015 | 9 | Stool Consistency Is Strongly Associated With Gut Microbiota Richness And Composition, Enterotypes And Bacterial Growth Rates IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The assessment of potentially confounding factors affecting colon microbiota composition is essential to the identification of robust microbiome based disease markers. Here, we … |
DORIS VANDEPUTTE et. al. |
2015 | 10 | HBV CccDNA: Viral Persistence Reservoir And Key Obstacle For A Cure Of Chronic Hepatitis B IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: At least 250 million people worldwide are chronically infected with HBV, a small hepatotropic DNA virus that replicates through reverse transcription. Chronic infection greatly … |
Michael Nassal; |
2014 | 1 | Hepatocellular Carcinoma: Clinical Frontiers And Perspectives IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death and is currently the main event leading to death in patients with cirrhosis. Evolving … |
Jordi Bruix; Gregory J Gores; Vincenzo Mazzaferro; |
2014 | 2 | Global Incidence Of Oesophageal Cancer By Histological Subtype In 2012 IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The two major histological types of oesophageal cancer–adenocarcinoma (AC) and squamous cell carcinoma (SCC)–are known to differ greatly in terms of risk factors and … |
Melina Arnold; Isabelle Soerjomataram; Jacques Ferlay; David Forman; |
2014 | 3 | Diagnosis And Management Of Adult Coeliac Disease: Guidelines From The British Society Of Gastroenterology IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: A multidisciplinary panel of 18 physicians and 3 non-physicians from eight countries (Sweden, UK, Argentina, Australia, Italy, Finland, Norway and the USA) reviewed the literature … |
JONAS F LUDVIGSSON et. al. |
2014 | 4 | Exercise And Associated Dietary Extremes Impact On Gut Microbial Diversity IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The commensal microbiota, host immunity and metabolism participate in a signalling network, with diet influencing each component of this triad. In addition to diet, many elements … |
SIOBHAN F CLARKE et. al. |
2014 | 5 | A Polyphenol-rich Cranberry Extract Protects From Diet-induced Obesity, Insulin Resistance And Intestinal Inflammation In Association With Increased Akkermansia Spp. Population In The Gut Microbiota Of Mice IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The increasing prevalence of obesity and type 2 diabetes (T2D) demonstrates the failure of conventional treatments to curb these diseases. The gut microbiota has been put forward … |
FERNANDO F ANHÊ et. al. |
2014 | 6 | Effects of Targeted Delivery of Propionate to The Human Colon on Appetite Regulation, Body Weight Maintenance and Adiposity in Overweight Adults IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The colonic microbiota ferment dietary fibres, producing short chain fatty acids. Recent evidence suggests that the short chain fatty acid propionate may play an important role in … |
EDWARD S CHAMBERS et. al. |
2014 | 7 | Diets That Differ In Their FODMAP Content Alter The Colonic Luminal Microenvironment IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: A low FODMAP (Fermentable Oligosaccharides, Disaccharides, Monosaccharides And Polyols) diet reduces symptoms of IBS, but reduction of potential prebiotic and fermentative effects … |
EMMA P HALMOS et. al. |
2014 | 8 | Microbiota And Diabetes: An Evolving Relationship IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The gut microbiota affects numerous biological functions throughout the body and its characterisation has become a major research area in biomedicine. Recent studies have … |
Herbert Tilg; Alexander R Moschen; |
2014 | 9 | Circulating MicroRNA Signature In Non-alcoholic Fatty Liver Disease: From Serum Non-coding RNAs To Liver Histology And Disease Pathogenesis IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: We used a screening strategy of global serum microRNA (miRNA) profiling, followed by a second stage of independent replication and exploration of liver expression of selected … |
CARLOS J PIROLA et. al. |
2014 | 10 | Iron Fortification Adversely Affects The Gut Microbiome, Increases Pathogen Abundance And Induces Intestinal Inflammation In Kenyan Infants IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: In-home iron fortification for infants in developing countries is recommended for control of anaemia, but low absorption typically results in >80% of the iron passing into the … |
TANJA JAEGGI et. al. |
2013 | 1 | Update On The Epidemiology Of Gastro-oesophageal Reflux Disease: A Systematic Review IF:8 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: To update the findings of the 2005 systematic review of population-based studies assessing the epidemiology of gastro-oesophageal reflux disease (GERD). PubMed and Embase were … |
Hashem B El-Serag; Stephen Sweet; Christopher C Winchester; John Dent; |
2013 | 2 | British Society of Gastroenterology Guidelines on The Diagnosis and Management of Barrett’s Oesophagus IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: These guidelines provide a practical and evidence-based resource for the management of patients with Barrett’s oesophagus and related early neoplasia. The Appraisal of Guidelines … |
REBECCA C FITZGERALD et. al. |
2013 | 3 | An Increase In The Akkermansia Spp. Population Induced By Metformin Treatment Improves Glucose Homeostasis In Diet-induced Obese Mice IF:8 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Recent evidence indicates that the composition of the gut microbiota contributes to the development of metabolic disorders by affecting the physiology and metabolism of the host. … |
NA-RI SHIN et. al. |
2013 | 4 | A Decrease Of The Butyrate-producing Species Roseburia Hominis And Faecalibacterium Prausnitzii Defines Dysbiosis In Patients With Ulcerative Colitis IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Bacteria play an important role in the onset and perpetuation of intestinal inflammation in inflammatory bowel disease (IBD). Unlike in Crohn’s disease (CD), in which dysbiosis … |
KATHLEEN MACHIELS et. al. |
2013 | 5 | Decreased Gut Microbiota Diversity, Delayed Bacteroidetes Colonisation And Reduced Th1 Responses In Infants Delivered By Caesarean Section IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The early intestinal microbiota exerts important stimuli for immune development, and a reduced microbial exposure as well as caesarean section (CS) has been associated with the … |
HEDVIG E JAKOBSSON et. al. |
2013 | 6 | Revised Guidelines For The Clinical Management Of Lynch Syndrome (HNPCC): Recommendations By A Group Of European Experts IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Lynch syndrome (LS) is characterised by the development of colorectal cancer, endometrial cancer and various other cancers, and is caused by a mutation in one of the mismatch … |
HANS F A VASEN et. al. |
2013 | 7 | Bacteria Penetrate The Normally Impenetrable Inner Colon Mucus Layer In Both Murine Colitis Models And Patients With Ulcerative Colitis IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The inner mucus layer in mouse colon normally separates bacteria from the epithelium. Do humans have a similar inner mucus layer and are defects in this mucus layer a common … |
MALIN E V JOHANSSON et. al. |
2013 | 8 | Prospective Evaluation Of Methylated SEPT9 In Plasma For Detection Of Asymptomatic Colorectal Cancer IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: As screening methods for colorectal cancer (CRC) are limited by uptake and adherence, further options are sought. A blood test might increase both, but none has yet been tested in … |
TIMOTHY ROBERT CHURCH et. al. |
2013 | 9 | Geographical Variability And Environmental Risk Factors In Inflammatory Bowel Disease IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The changing epidemiology of inflammatory bowel disease (IBD) across time and geography suggests that environmental factors play a major role in modifying disease expression. … |
SIEW C NG et. al. |
2013 | 10 | An Update On The Use And Investigation Of Probiotics In Health And Disease IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Probiotics are derived from traditional fermented foods, from beneficial commensals or from the environment. They act through diverse mechanisms affecting the composition or … |
MARY ELLEN SANDERS et. al. |
2012 | 1 | The Oslo Definitions For Coeliac Disease And Related Terms IF:8 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The literature suggests a lack of consensus on the use of terms related to coeliac disease (CD) and gluten. A multidisciplinary task force of 16 physicians from seven countries … |
JONAS F LUDVIGSSON et. al. |
2012 | 2 | Secukinumab, A Human Anti-IL-17A Monoclonal Antibody, For Moderate To Severe Crohn’s Disease: Unexpected Results Of A Randomised, Double-blind Placebo-controlled Trial IF:8 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The authors tested whether the anti-interleukin (IL)-17A monoclonal antibody secukinumab was safe and effective for the treatment of active Crohn’s disease. In a double-blind, … |
WOLFGANG HUEBER et. al. |
2012 | 3 | Helicobacter Pylori Resistance To Antibiotics In Europe And Its Relationship To Antibiotic Consumption IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Resistance to antibiotics is the major cause of treatment failure of Helicobacter pylori infection. A study was conducted to assess prospectively the antibacterial resistance … |
FRANCIS MEGRAUD et. al. |
2012 | 4 | Intestinal Microbiota In Functional Bowel Disorders: A Rome Foundation Report IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: It is increasingly perceived that gut host-microbial interactions are important elements in the pathogenesis of functional gastrointestinal disorders (FGID). The most convincing … |
MAGNUS SIMRÉN et. al. |
2012 | 5 | Hyaluronan Impairs Vascular Function And Drug Delivery In A Mouse Model Of Pancreatic Cancer IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Pancreatic ductal adenocarcinoma (PDA) is characterised by stromal desmoplasia and vascular dysfunction, which critically impair drug delivery. This study examines the role of an … |
MICHAEL A JACOBETZ et. al. |
2012 | 6 | Guidelines For The Diagnosis And Treatment Of Cholangiocarcinoma: An Update IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The British Society of Gastroenterology guidelines on the management of cholangiocarcinoma were originally published in 2002. This is the first update since then and is based on a … |
SHAHID A KHAN et. al. |
2012 | 7 | Mucosal Healing In Inflammatory Bowel Diseases: A Systematic Review IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Recent studies have identified mucosal healing on endoscopy as a key prognostic parameter in the management of inflammatory bowel diseases (IBD), thus highlighting the role of … |
Markus F Neurath; Simon P L Travis; |
2012 | 8 | International Cancer Of The Pancreas Screening (CAPS) Consortium Summit On The Management Of Patients With Increased Risk For Familial Pancreatic Cancer IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Screening individuals at increased risk for pancreatic cancer (PC) detects early, potentially curable, pancreatic neoplasia. To develop consortium statements on screening, … |
MARCIA IRENE CANTO et. al. |
2012 | 9 | Intestinal Microbiota Determines Development Of Non-alcoholic Fatty Liver Disease In Mice IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Non-alcoholic fatty liver disease (NAFLD) is prevalent among obese people and is considered the hepatic manifestation of metabolic syndrome. However, not all obese individuals … |
TIPHAINE LE ROY et. al. |
2012 | 10 | A Comprehensive Survey Of Genomic Alterations In Gastric Cancer Reveals Systematic Patterns Of Molecular Exclusivity And Co-occurrence Among Distinct Therapeutic Targets IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Gastric cancer is a major gastrointestinal malignancy for which targeted therapies are emerging as treatment options. This study sought to identify the most prevalent molecular … |
NIANTAO DENG et. al. |
2011 | 1 | Guidelines For The Management Of Inflammatory Bowel Disease In Adults IF:8 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The management of inflammatory bowel disease represents a key component of clinical practice for members of the British Society of Gastroenterology (BSG). There has been … |
CRAIG MOWAT et. al. |
2011 | 2 | Guidelines for The Management of Gastroenteropancreatic Neuroendocrine (including Carcinoid) Tumours (NETs) IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: These guidelines update previous guidance published in 2005. They have been revised by a group who are members of the UK and Ireland Neuroendocrine Tumour Society with endorsement … |
JOHN K RAMAGE et. al. |
2011 | 3 | Dysbiosis Of The Faecal Microbiota In Patients With Crohn’s Disease And Their Unaffected Relatives IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: A general dysbiosis of the intestinal microbiota has been established in patients with Crohn’s disease (CD), but a systematic characterisation of this dysbiosis is lacking. … |
MARIE JOOSSENS et. al. |
2011 | 4 | Adalimumab For Induction Of Clinical Remission In Moderately To Severely Active Ulcerative Colitis: Results Of A Randomised Controlled Trial IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The aim of this study was to assess the efficacy and safety of adalimumab (ADA), a recombinant human monoclonal antibody against tumour necrosis factor α (TNF), for the induction … |
WALTER REINISCH et. al. |
2011 | 5 | An Irritable Bowel Syndrome Subtype Defined By Species-specific Alterations In Faecal Microbiota IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder that may be triggered by enteric pathogens and has also been linked to alterations in the … |
IAN B JEFFERY et. al. |
2011 | 6 | New IBD Genetics: Common Pathways With Other Diseases IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Complex disease genetics has been revolutionised in recent years by the advent of genome-wide association (GWA) studies. The chronic inflammatory bowel diseases (IBDs), Crohn’s … |
C W Lees; J C Barrett; M Parkes; J Satsangi; |
2011 | 7 | Guidelines For The Management Of Iron Deficiency Anaemia IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Iron deficiency anaemia (IDA) occurs in 2-5% of adult men and postmenopausal women in the developed world and is a common cause of referral to gastroenterologists. … |
Andrew F Goddard; Martin W James; Alistair S McIntyre; Brian B Scott; BB; |
2011 | 8 | Longitudinal Study Of Infectious Intestinal Disease In The UK (IID2 Study): Incidence In The Community And Presenting To General Practice IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: To estimate, overall and by organism, the incidence of infectious intestinal disease (IID) in the community, presenting to general practice (GP) and reported to national … |
CLARENCE C TAM et. al. |
2011 | 9 | The Incidence Of Oesophageal Adenocarcinoma In Non-dysplastic Barrett’s Oesophagus: A Meta-analysis IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The risk of oesophageal adenocarcinoma (OAC) in non-dysplastic Barrett’s oesophagus (BO) may have been overestimated. The objective was to estimate the incidence of OAC in … |
TUSAR K DESAI et. al. |
2011 | 10 | Metabolic Adaptation To A High-fat Diet Is Associated With A Change In The Gut Microbiota IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The gut microbiota, which is considered a causal factor in metabolic diseases as shown best in animals, is under the dual influence of the host genome and nutritional environment. … |
MATTEO SERINO et. al. |
2010 | 1 | Guidelines For Colorectal Cancer Screening And Surveillance In Moderate And High Risk Groups (update From 2002) IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The British Society of Gastroenterology (BSG) and the Association of Coloproctology for Great Britain and Ireland (ACPGBI) commissioned this update of the 2002 guidance. The aim, … |
STUART R CAIRNS et. al. |
2010 | 2 | Helicobacter Pylori Treatment In The Era Of Increasing Antibiotic Resistance IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: With few exceptions, the most commonly recommended triple Helicobacter pylori regimen (proton pump inhibitor (PPI), amoxicillin and clarithromycin) now provides unacceptably low … |
David Y Graham; Lori Fischbach; |
2010 | 3 | Composition And Energy Harvesting Capacity Of The Gut Microbiota: Relationship To Diet, Obesity And Time In Mouse Models IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Increased efficiency of energy harvest, due to alterations in the gut microbiota (increased Firmicutes and decreased Bacteroidetes), has been implicated in obesity in mice and … |
E F MURPHY et. al. |
2010 | 4 | Stromal Biology And Therapy In Pancreatic Cancer IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Pancreatic ductal adenocarcinoma (PDA) is an almost uniformly lethal disease. One explanation for the devastating prognosis is the failure of many chemotherapies, including the … |
ALBRECHT NEESSE et. al. |
2010 | 5 | Autologous Bone Marrow-derived Mesenchymal Stromal Cell Treatment For Refractory Luminal Crohn’s Disease: Results Of A Phase I Study IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Mesenchymal stromal cells (MSCs) are pluripotent cells that have immunosuppressive effects both in vitro and in experimental colitis. Promising results of MSC therapy have been … |
MARJOLIJN DUIJVESTEIN et. al. |
2010 | 6 | Bacterial Infection Causes Stress-induced Memory Dysfunction In Mice IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The brain-gut axis is a key regulator of normal intestinal physiology; for example, psychological stress is linked to altered gut barrier function, development of food allergies … |
MÉLANIE G GAREAU et. al. |
2010 | 7 | Simple Non-invasive Fibrosis Scoring Systems Can Reliably Exclude Advanced Fibrosis In Patients With Non-alcoholic Fatty Liver Disease IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Accurate evaluation of liver fibrosis in patients with non-alcoholic fatty liver disease (NAFLD) is important to identify patients who may develop complications. The aim of this … |
Stuart McPherson; Stephen F Stewart; Elsbeth Henderson; Alastair D Burt; Christopher P Day; |
2010 | 8 | Molecular Pathological Epidemiology Of Colorectal Neoplasia: An Emerging Transdisciplinary And Interdisciplinary Field IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Colorectal cancer is a complex disease resulting from somatic genetic and epigenetic alterations, including locus-specific CpG island methylation and global DNA or LINE-1 … |
Shuji Ogino; Andrew T Chan; Charles S Fuchs; Edward Giovannucci; |
2010 | 9 | Colitis Induced In Mice With Dextran Sulfate Sodium (DSS) Is Mediated By The NLRP3 Inflammasome IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The proinflammatory cytokines interleukin 1beta (IL-1beta) and IL-18 are central players in the pathogenesis of inflammatory bowel disease (IBD). In response to a variety of … |
CHRISTIAN BAUER et. al. |
2010 | 10 | Antibiotic Use And Inflammatory Bowel Diseases In Childhood IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The composition of the intestinal microflora has been proposed as an important factor in the development of inflammatory bowel diseases (IBD). Antibiotics have the potential to … |
Anders Hviid; Henrik Svanström; Morten Frisch; |