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Most Influential ANNALS OF INTERNAL MEDICINE Papers

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Annals of Internal Medicine is an academic medical journal published by the American College of Physicians (ACP). It is one of the most widely cited and influential specialty medical journals in the world. Paper Digest Team analyze all papers published on ANNALS OF INTERNAL MEDICINE in the past years, and presents the 10 most influential papers for each year (based on when the paper became available online). This ranking list is automatically constructed based upon citations from both research papers and granted patents, and will be frequently updated to reflect the most recent changes. To find the most influential papers from other conferences/journals, visit Best Paper Digest page. Note: the most influential papers may or may not include the papers that won the best paper awards. (Last updated on: 2021-05-23)

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TABLE 1: Most Influential ANNALS OF INTERNAL MEDICINE Papers

Year Rank Paper Author(s)
2020 1 The Incubation Period Of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation And Application
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Abstract: A novel human coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified in China in December 2019. There is limited support for many of its key …		 STEPHEN A LAUER et. al.
2020 2 Autopsy Findings And Venous Thromboembolism In Patients With COVID-19
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 Dominic Wichmann;
2020 3 Prevalence of Asymptomatic SARS-CoV-2 Infection
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Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread rapidly throughout the world since the first cases of coronavirus disease 2019 (COVID-19) were observed in …		 Daniel P Oran; Eric J Topol;
2020 4 Psychological Impact of The COVID-19 Pandemic on Health Care Workers in Singapore
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 BENJAMIN Y Q TAN et. al.
2020 5 COVID-19 and The Risk to Health Care Workers: A Case Report
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 KANGQI NG et. al.
2020 6 Pulmonary Arterial Thrombosis in COVID-19 With Fatal Outcome: Results From A Prospective, Single-Center, Clinicopathologic Case Series
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Abstract: Background: Coronavirus disease 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly become pandemic, with substantial …		 SIGURD F LAX et. al.
2020 7 Collision of The COVID-19 and Addiction Epidemics
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 Nora D Volkow;
2020 8 Hydroxychloroquine in Nonhospitalized Adults With Early COVID-19
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Abstract: There is no known effective oral therapy for early COVID-19. This randomized, double-blind, placebo-controlled trial evaluated effects of oral hydroxychloroquine on symptoms and …		 CALEB P SKIPPER et. al.
2020 9 Systemic Lupus Erythematosus
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Abstract: Systemic lupus erythematosus (lupus) is characterized by aberrant activity of the immune system, leading to variable clinical symptoms. Lupus is more prevalent in African American …		 Marianthi Kiriakidou; Cathy Lee Ching;
2020 10 Awareness, Attitudes, and Actions Related to COVID-19 Among Adults With Chronic Conditions at The Onset of The U.S. Outbreak
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Abstract: Background: The evolving outbreak of coronavirus disease 2019 (COVID-19) is requiring social distancing and other measures to protect public health. However, messaging has been …		 MICHAEL S WOLF et. al.
2019 1 PROBAST: A Tool To Assess The Risk Of Bias And Applicability Of Prediction Model Studies
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Abstract: Clinical prediction models combine multiple predictors to estimate risk for the presence of a particular condition (diagnostic models) or the occurrence of a certain event in the …		 ROBERT F WOLFF et. al.
2019 2 Rheumatoid Arthritis
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Abstract: Rheumatoid arthritis (RA) is a common systemic inflammatory autoimmune disease characterized by painful, swollen joints that can severely impair physical function and quality of …		 Jeffrey A Sparks;
2019 3 Estimating The Attributable Cost Of Physician Burnout In The United States
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Abstract: Although physician burnout is associated with negative clinical and organizational outcomes, its economic costs are poorly understood. As a result, leaders in health care cannot …		 SHASHA HAN et. al.
2019 4 PROBAST: A Tool To Assess Risk Of Bias And Applicability Of Prediction Model Studies: Explanation And Elaboration
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Abstract: Prediction models in health care use predictors to estimate for an individual the probability that a condition or disease is already present (diagnostic model) or will occur in …		 KAREL G M MOONS et. al.
2019 5 Birth
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 Kelly E Largent;
2019 6 Detection of Various Microplastics in Human Stool
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Abstract: In the past century, global production of plastics has grown exponentially to more than 350 million tons per year, part of which ends up littering the environment (1, 2). …		 PHILIPP SCHWABL et. al.
2019 7 Cross-Sex Hormones And Acute Cardiovascular Events In Transgender Persons
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 Michael Goodman; Darios Getahun; Michael J Silverberg; Joshua Safer; Vin Tangpricha;
2019 8 Unprocessed Red Meat And Processed Meat Consumption: Dietary Guideline Recommendations From The Nutritional Recommendations (NutriRECS) Consortium
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Abstract: This article has been corrected. The original version (PDF) is appended to this article as a Supplement. Dietary guideline recommendations require consideration of the certainty …		 BRADLEY C JOHNSTON et. al.
2019 9 Fournier Gangrene Associated With Sodium-Glucose Cotransporter-2 Inhibitors: A Review Of Spontaneous Postmarketing Cases
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Abstract: Use of sodium-glucose cotransporter-2 (SGLT2) inhibitors has been associated with Fournier gangrene (FG), a rare urologic emergency characterized by necrotizing infection of the …		 Susan J Bersoff-Matcha; Christine Chamberlain; Christian Cao; Cindy Kortepeter; William H Chong;
2019 10 Measles, Mumps, Rubella Vaccination And Autism
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 Anders Hviid; Jørgen Vinsløv Hansen; Morten Frisch; Mads Melbye;
2018 1 PRISMA Extension For Scoping Reviews (PRISMA-ScR): Checklist And Explanation
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Abstract: Scoping reviews, a type of knowledge synthesis, follow a systematic approach to map evidence on a topic and identify main concepts, theories, sources, and knowledge gaps. Although …		 ANDREA C TRICCO et. al.
2018 2 Psoriasis
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Abstract: Psoriasis, an inherited disorder of the immune system, presents most commonly in the skin and joints but is also associated with cardiovascular, metabolic, and neuropsychiatric …		 Mark Lebwohl;
2018 3 Medication for Opioid Use Disorder After Nonfatal Opioid Overdose and Association With Mortality
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Abstract: The United States is in the midst of a crisis of opioid-related harms (1). Some efforts to address this crisis focus on expanding access to effective treatment of opioid use …		 MARC R LAROCHELLE et. al.
2018 4 Nonalcoholic Fatty Liver Disease
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Abstract: Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease. Most cases are diagnosed incidentally in the primary care or hospital setting on the basis …		 Xiao Jing Wang; Harmeet Malhi;
2018 5 Real-Time Use of Artificial Intelligence in Identification of Diminutive Polyps During Colonoscopy
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Abstract: Colonoscopy is considered the gold standard for decreasing colorectal cancer incidence and mortality (1). To maximize the benefits and cost-effectiveness of colonoscopy, resection …		 YUICHI MORI et. al.
2018 6 Hemoglobin A1c Targets For Glycemic Control With Pharmacologic Therapy For Nonpregnant Adults With Type 2 Diabetes Mellitus: A Guidance Statement Update From The American College Of Physicians
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Abstract: The American College of Physicians developed this guidance statement to guide clinicians in selecting targets for pharmacologic treatment of type 2 diabetes. The National …		 AMIR QASEEM et. al.
2018 7 Prevalence And Distribution Of E-Cigarette Use Among U.S. Adults: Behavioral Risk Factor Surveillance System, 2016
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Abstract: Contemporary data on the prevalence of e-cigarette use in the United States are limited. To report the prevalence and distribution of current e-cigarette use among U.S. adults in …		 MOHAMMADHASSAN MIRBOLOUK et. al.
2018 8 Addressing Social Determinants To Improve Patient Care And Promote Health Equity: An American College Of Physicians Position Paper
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Abstract: Social determinants of health are nonmedical factors that can affect a person’s overall health and health outcomes. Where a person is born and the social conditions they are born …		 Hilary Daniel; Sue S Bornstein; Gregory C Kane; GC;
2018 9 Prevention, Detection, Evaluation, And Management Of High Blood Pressure In Adults: Synopsis Of The 2017 American College Of Cardiology/American Heart Association Hypertension Guideline
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Abstract: In November 2017, the American College of Cardiology (ACC) and the American Heart Association (AHA) released a clinical practice guideline for the prevention, detection, …		 Robert M Carey; Paul K Whelton; PK;
2018 10 Use Of Immune Checkpoint Inhibitors In The Treatment Of Patients With Cancer And Preexisting Autoimmune Disease
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 Noha Abdel-Wahab; Mohsin Shah; Maria A Lopez-Olivo; Maria E Suarez-Almazor;
2017 1 Noninvasive Treatments For Acute, Subacute, And Chronic Low Back Pain: A Clinical Practice Guideline From The American College Of Physicians
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Abstract: The American College of Physicians (ACP) developed this guideline to present the evidence and provide clinical recommendations on noninvasive treatment of low back pain. Using the …		 Amir Qaseem; Timothy J Wilt; Robert M McLean; Mary Ann Forciea; MA;
2017 2 Sensitivity Analysis In Observational Research: Introducing The E-Value
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Abstract: Sensitivity analysis is useful in assessing how robust an association is to potential unmeasured or uncontrolled confounding. This article introduces a new measure called the …		 Tyler J VanderWeele; Peng Ding;
2017 3 Prescription Opioid Use, Misuse, And Use Disorders In U.S. Adults: 2015 National Survey On Drug Use And Health
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Abstract: Despite the continuing epidemic of opioid misuse, data on the prevalence of prescription opioid use, misuse, and use disorders are limited. To estimate the prevalence of …		 BETH HAN et. al.
2017 4 CONSORT Statement For Randomized Trials Of Nonpharmacologic Treatments: A 2017 Update And A CONSORT Extension For Nonpharmacologic Trial Abstracts
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Abstract: Incomplete and inadequate reporting is an avoidable waste that reduces the usefulness of research. The CONSORT (Consolidated Standards of Reporting Trials) Statement is an …		 ISABELLE BOUTRON et. al.
2017 5 Oral Direct-Acting Agent Therapy For Hepatitis C Virus Infection: A Systematic Review
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Abstract: Rapid improvements in hepatitis C virus (HCV) therapy have led to the approval of multiple oral direct-acting antiviral (DAA) regimens by the U.S. Food and Drug Administration …		 OLUWASEUN FALADE-NWULIA et. al.
2017 6 Nicotine, Carcinogen, and Toxin Exposure in Long-Term E-Cigarette and Nicotine Replacement Therapy Users
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Abstract: E-cigarettes (1), which produce an aerosol by heating a solvent (e-liquid) usually containing nicotine through a battery-powered heating element, are becoming increasingly …		 LION SHAHAB et. al.
2017 7 Systemic Pharmacologic Therapies For Low Back Pain: A Systematic Review For An American College Of Physicians Clinical Practice Guideline
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Abstract: A 2007 American College of Physicians guideline addressed pharmacologic options for low back pain. New evidence and medications have now become available. To review the current …		 ROGER CHOU et. al.
2017 8 Treatment Of Low Bone Density Or Osteoporosis To Prevent Fractures In Men And Women: A Clinical Practice Guideline Update From The American College Of Physicians
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Abstract: This guideline updates the 2008 American College of Physicians (ACP) recommendations on treatment of low bone density and osteoporosis to prevent fractures in men and women. This …		 Amir Qaseem; Mary Ann Forciea; Robert M McLean; Thomas D Denberg; TD;
2017 9 Pharmacologic Treatment Of Hypertension In Adults Aged 60 Years Or Older To Higher Versus Lower Blood Pressure Targets: A Clinical Practice Guideline From The American College Of Physicians And The American Academy Of Family Physicians
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Abstract: The American College of Physicians (ACP) and the American Academy of Family Physicians (AAFP) jointly developed this guideline to present the evidence and provide clinical …		 AMIR QASEEM et. al.
2017 10 Nonpharmacologic Therapies For Low Back Pain: A Systematic Review For An American College Of Physicians Clinical Practice Guideline
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Abstract: A 2007 American College of Physicians guideline addressed nonpharmacologic treatment options for low back pain. New evidence is now available. To systematically review the current …		 ROGER CHOU et. al.
2016 1 Screening For Breast Cancer: U.S. Preventive Services Task Force Recommendation Statement
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Abstract: Update of the 2009 U.S. Preventive Services Task Force (USPSTF) recommendation on screening for breast cancer. The USPSTF reviewed the evidence on the following: effectiveness of …		 Albert L Siu; AL;
2016 2 Allocation Of Physician Time In Ambulatory Practice: A Time And Motion Study In 4 Specialties
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Abstract: Little is known about how physician time is allocated in ambulatory care. To describe how physician time is spent in ambulatory practice. Quantitative direct observational time …		 CHRISTINE SINSKY et. al.
2016 3 Management Of Chronic Insomnia Disorder In Adults: A Clinical Practice Guideline From The American College Of Physicians
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Abstract: The American College of Physicians (ACP) developed this guideline to present the evidence and provide clinical recommendations on the management of chronic insomnia disorder in …		 AMIR QASEEM et. al.
2016 4 Hepatitis C Virus
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Abstract: This issue provides a clinical overview of hepatitis C virus, focusing on transmission, prevention, screening, diagnosis, evaluation, and treatment. The content of In the Clinic …		 Arthur Kim;
2016 5 Aspirin Use For The Primary Prevention Of Cardiovascular Disease And Colorectal Cancer: U.S. Preventive Services Task Force Recommendation Statement
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Abstract: Update of the 2009 USPSTF recommendation on aspirin use to prevent cardiovascular disease (CVD) events and the 2007 recommendation on aspirin and nonsteroidal anti-inflammatory …		 Kirsten Bibbins-Domingo; K;
2016 6 Diagnosis And Management Of Diabetes: Synopsis Of The 2016 American Diabetes Association Standards Of Medical Care In Diabetes
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Abstract: The American Diabetes Association (ADA) published the 2016 Standards of Medical Care in Diabetes (Standards) to provide clinicians, patients, researchers, payers, and other …		 James J Chamberlain; Andrew S Rhinehart; Charles F Shaefer; Annie Neuman;
2016 7 Diabetes Medications As Monotherapy Or Metformin-Based Combination Therapy for Type 2 Diabetes
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Abstract: Type 2 diabetes and its complications are a substantial public health burden, affecting 9.3% of the U.S. adult population (1, 2). Most patients with type 2 diabetes eventually …		 NISA M MARUTHUR et. al.
2016 8 Early Coverage, Access, Utilization, and Health Effects Associated With The Affordable Care Act Medicaid Expansions
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Abstract: Context The effect on health care and patient outcomes of the 2014 state Medicaid expansions for low-income adults is of interest to politicians, policymakers, insurers, and the …		 Laura R Wherry; Sarah Miller;
2016 9 Cognitive Behavioral Therapy For Chronic Insomnia
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 James M Trauer; David Cunnington;
2016 10 Long-Term Pioglitazone Treatment for Patients With Nonalcoholic Steatohepatitis and Prediabetes Or Type 2 Diabetes Mellitus
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Abstract: Nonalcoholic fatty liver disease (NAFLD) is reaching epidemic proportions worldwide (1) and is the most common chronic liver condition in obese patients with prediabetes or type 2 …		 KENNETH CUSI et. al.
2015 1 The PRISMA Extension Statement For Reporting Of Systematic Reviews Incorporating Network Meta-analyses Of Health Care Interventions: Checklist And Explanations
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Abstract: The PRISMA statement is a reporting guideline designed to improve the completeness of reporting of systematic reviews and meta-analyses. Authors have used this guideline worldwide …		 BRIAN HUTTON et. al.
2015 2 Sedentary Time and Its Association With Risk for Disease Incidence, Mortality, and Hospitalization in Adults
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Abstract: Adults are advised to accumulate at least 150 minutes of weekly physical activity in bouts of 10 minutes or more (1). The intensity of such habitual physical activity has been …		 AVIROOP BISWAS et. al.
2015 3 Transparent Reporting Of A Multivariable Prediction Model For Individual Prognosis Or Diagnosis (TRIPOD): Explanation And Elaboration
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Abstract: The TRIPOD (Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis) Statement includes a 22-item checklist, which aims to improve the …		 KAREL G M MOONS et. al.
2015 4 The Effectiveness And Risks Of Long-term Opioid Therapy For Chronic Pain: A Systematic Review For A National Institutes Of Health Pathways To Prevention Workshop
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Abstract: Increases in prescriptions of opioid medications for chronic pain have been accompanied by increases in opioid overdoses, abuse, and other harms and uncertainty about long-term …		 ROGER CHOU et. al.
2015 5 Transparent Reporting Of A Multivariable Prediction Model For Individual Prognosis Or Diagnosis (TRIPOD): The TRIPOD Statement
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Abstract: Prediction models are developed to aid health care providers in estimating the probability or risk that a specific disease or condition is present (diagnostic models) or that a …		 Gary S Collins; Johannes B Reitsma; Douglas G Altman; Karel G M Moons;
2015 6 Combination Antifungal Therapy for Invasive Aspergillosis
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Abstract: Editors’ Notes Context Invasive aspergillosis (IA) is a life-threatening disease in patients with hematologic malignancies and hemato-poietic cell transplantation. Contribution In …		 KIEREN MARR et. al.
2015 7 Restrictions For Medicaid Reimbursement Of Sofosbuvir For The Treatment Of Hepatitis C Virus Infection In The United States
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Abstract: The aim of this study was to systematically evaluate state Medicaid policies for the treatment of hepatitis C virus (HCV) infection with sofosbuvir in the United States. Medicaid …		 SOUMITRI BARUA et. al.
2015 8 Effects Of Proprotein Convertase Subtilisin/Kexin Type 9 Antibodies In Adults With Hypercholesterolemia: A Systematic Review And Meta-analysis
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Abstract: Guidelines recommend statins as first-line therapy for dyslipidemia. Monoclonal antibodies targeting proprotein convertase subtilisin/kexin type 9 (PCSK9) is a new lipid-lowering …		 ELIANO PIO NAVARESE et. al.
2015 9 An Analysis Of Calibration And Discrimination Among Multiple Cardiovascular Risk Scores In A Modern Multiethnic Cohort
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Abstract: Accurate risk assessment of atherosclerotic cardiovascular disease (ASCVD) is essential to effectively balance the risks and benefits of therapy for primary prevention. To compare …		 ANDREW P DEFILIPPIS et. al.
2015 10 Cost-effectiveness And Budget Impact Of Hepatitis C Virus Treatment With Sofosbuvir And Ledipasvir In The United States
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Abstract: Sofosbuvir and ledipasvir, which have recently been approved for treatment of chronic hepatitis C virus (HCV) infection, are more efficacious and safer than the old standard of …		 Jagpreet Chhatwal; Fasiha Kanwal; Mark S Roberts; Michael A Dunn;
2014 1 Screening For Lung Cancer: U.S. Preventive Services Task Force Recommendation Statement
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Abstract: Update of the 2004 U.S. Preventive Services Task Force (USPSTF) recommendation on screening for lung cancer. The USPSTF reviewed the evidence on the efficacy of low-dose computed …		 Virginia A Moyer; VA;
2014 2 Association Of Dietary, Circulating, And Supplement Fatty Acids With Coronary Risk: A Systematic Review And Meta-analysis
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Abstract: Guidelines advocate changes in fatty acid consumption to promote cardiovascular health. To summarize evidence about associations between fatty acids and coronary disease. MEDLINE, …		 RAJIV CHOWDHURY et. al.
2014 3 Chronic Hepatitis C Virus Infection In The United States, National Health And Nutrition Examination Survey 2003 To 2010
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Abstract: Knowledge of the number of persons with chronic hepatitis C virus (HCV) infection in the United States is critical for public health and policy planning. To estimate the …		 MAXINE M DENNISTON et. al.
2014 4 Transitional Care Interventions to Prevent Readmissions for Persons With Heart Failure
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Abstract: Heart failure (HF) is a leading cause of hospitalization and health care costs in the United States (1). Up to 25% of patients hospitalized with HF are readmitted within 30 days …		 CYNTHIA FELTNER et. al.
2014 5 Platelet Transfusion: A Clinical Practice Guideline From The AABB
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Abstract: The AABB (formerly, the American Association of Blood Banks) developed this guideline on appropriate use of platelet transfusion in adult patients. These guidelines are based on a …		 RICHARD M KAUFMAN et. al.
2014 6 Accuracy of Fecal Immunochemical Tests for Colorectal Cancer
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Abstract: Colorectal cancer (CRC) is the second-leading cause of cancer-related deaths in the United States (1). Randomized, controlled trials have shown that annual or biennial fecal …		 Jeffrey K Lee; Elizabeth G Liles; Stephen Bent; Theodore R Levin; Douglas A Corley;
2014 7 Health Information Technology: An Updated Systematic Review With A Focus On Meaningful Use
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Abstract: Incentives offered by the U.S. government have spurred marked increases in use of health information technology (IT). To update previous reviews and examine recent evidence that …		 Spencer S Jones; Robert S Rudin; Tanja Perry; Paul G Shekelle;
2014 8 Antiretroviral-Free HIV-1 Remission and Viral Rebound After Allogeneic Stem Cell Transplantation
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Abstract: Context Because HIV can be detected in patients even when they are receiving long-term suppressive antiretroviral therapy (ART) and can rebound within weeks of stopping, HIV …		 TIMOTHY J HENRICH et. al.
2014 9 Evidence Supporting A Systolic Blood Pressure Goal Of Less Than 150 Mm Hg In Patients Aged 60 Years Or Older: The Minority View
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 Jackson T Wright; Lawrence J Fine; Daniel T Lackland; Gbenga Ogedegbe; Cheryl R Dennison Himmelfarb;
2014 10 Benefits And Harms Of Computed Tomography Lung Cancer Screening Strategies: A Comparative Modeling Study For The U.S. Preventive Services Task Force
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Abstract: The optimum screening policy for lung cancer is unknown. To identify efficient computed tomography (CT) screening scenarios in which relatively more lung cancer deaths are averted …		 HARRY J DE KONING et. al.
2013 1 SPIRIT 2013 Statement: Defining Standard Protocol Items For Clinical Trials
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Abstract: The protocol of a clinical trial serves as the foundation for study planning, conduct, reporting, and appraisal. However, trial protocols and existing protocol guidelines vary …		 AN-WEN CHAN et. al.
2013 2 Assessing Bias In Studies Of Prognostic Factors
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Abstract: Previous work has identified 6 important areas to consider when evaluating validity and bias in studies of prognostic factors: participation, attrition, prognostic factor …		 Jill A Hayden; Danielle A van der Windt; Jennifer L Cartwright; Pierre Côté; Claire Bombardier;
2013 3 Evaluation And Management Of Chronic Kidney Disease: Synopsis Of The Kidney Disease: Improving Global Outcomes 2012 Clinical Practice Guideline
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Abstract: The Kidney Disease: Improving Global Outcomes (KDIGO) organization developed clinical practice guidelines in 2012 to provide guidance on the evaluation, management, and treatment …		 Paul E Stevens; Adeera Levin; A;
2013 4 Eradication of Hepatitis C Virus Infection and The Development of Hepatocellular Carcinoma
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Abstract: BACKGROUND Hepatitis C virus (HCV) is a leading cause of hepatocellular carcinoma (HCC). In the United States, this form of cancer occurs in approximately 15 000 persons annually. …		 REBECCA L MORGAN et. al.
2013 5 Are Metabolically Healthy Overweight and Obesity Benign Conditions?
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Abstract: BACKGROUND Recent interest has focused on a unique subgroup of overweight and obese individuals who have normal metabolic features despite increased adiposity. Normal-weight …		 Caroline K Kramer; Bernard Zinman; Ravi Retnakaran;
2013 6 Viscosupplementation For Osteoarthritis Of The Knee
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 Peter Jüni; Anne W S Rutjes; Bruno R da Costa; Stephan Reichenbach;
2013 7 Conceptual And Technical Challenges In Network Meta-analysis
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Abstract: The increase in treatment options creates an urgent need for comparative effectiveness research. Randomized, controlled trials comparing several treatments are usually not …		 Andrea Cipriani; Julian P T Higgins; John R Geddes; Georgia Salanti;
2013 8 Promoting A Culture of Safety As A Patient Safety Strategy
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Abstract: Developing a culture of safety is a core element of many efforts to improve patient safety and care quality. This systematic review identifies and assesses interventions used to …		 SALLIE J. WEAVER et. al.
2013 9 Electronic Patient Portals: Evidence on Health Outcomes, Satisfaction, Efficiency, and Attitudes
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Abstract: BACKGROUND Patient portals tied to provider electronic health record (EHR) systems are increasingly popular. PURPOSE To systematically review the literature reporting the effect …		 CAROLINE GOLDZWEIG et. al.
2013 10 Screening For Lung Cancer With Low-dose Computed Tomography: A Systematic Review To Update The US Preventive Services Task Force Recommendation
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Abstract: Lung cancer is the leading cause of cancer-related death in the United States. Because early-stage lung cancer is associated with lower mortality than late-stage disease, early …		 LINDA L HUMPHREY et. al.
2012 1 Screening For Prostate Cancer: U.S. Preventive Services Task Force Recommendation Statement
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Abstract: Update of the 2008 U.S. Preventive Services Task Force (USPSTF) recommendation statement on screening for prostate cancer. The USPSTF reviewed new evidence on the benefits and …		 Virginia A Moyer; VA;
2012 2 Red Blood Cell Transfusion: A Clinical Practice Guideline From The AABB*
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Abstract: Although approximately 85 million units of red blood cells (RBCs) are transfused annually worldwide, transfusion practices vary widely. The AABB (formerly, the American …		 JEFFREY L CARSON et. al.
2012 3 Screening For Cervical Cancer: U.S. Preventive Services Task Force Recommendation Statement
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Abstract: Update of the 2003 U.S. Preventive Services Task Force (USPSTF) recommendation statement on screening for cervical cancer. The USPSTF reviewed new evidence on the comparative test …		 Virginia A Moyer; VA;
2012 4 Influence Of Reported Study Design Characteristics On Intervention Effect Estimates From Randomized, Controlled Trials
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Abstract: Published evidence suggests that aspects of trial design lead to biased intervention effect estimates, but findings from different studies are inconsistent. This study combined …		 JELENA SAVOVIĆ et. al.
2012 5 The Increasing Burden Of Mortality From Viral Hepatitis In The United States Between 1999 And 2007
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Abstract: The increasing health burden and mortality from hepatitis B virus (HBV) and hepatitis C virus (HCV) in the United States are underappreciated. To examine mortality from HBV; HCV; …		 KATHLEEN N LY et. al.
2012 6 Effect of Clinical Decision-Support Systems
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Abstract: BACKGROUND Despite increasing emphasis on the role of clinical decision-support systems (CDSSs) for improving care and reducing costs, evidence to support widespread use is …		 TIFFANI J BRIGHT et. al.
2012 7 A Multidimensional Index And Staging System For Idiopathic Pulmonary Fibrosis
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Abstract: Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease with an overall poor prognosis. A simple-to-use staging system for IPF may improve prognostication, help …		 BRETT LEY et. al.
2012 8 Guidelines For Improving Entry Into And Retention In Care And Antiretroviral Adherence For Persons With HIV: Evidence-based Recommendations From An International Association Of Physicians In AIDS Care Panel
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Abstract: After HIV diagnosis, timely entry into HIV medical care and retention in that care are essential to the provision of effective antiretroviral therapy (ART). Adherence to ART is …		 MELANIE A THOMPSON et. al.
2012 9 Interventions to Improve Adherence to Self-administered Medications for Chronic Diseases in The United States
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Abstract: BACKGROUND Suboptimum medication adherence is common in the United States and leads to serious negative health consequences but may respond to intervention. PURPOSE To assess the …		 MEERA VISWANATHAN et. al.
2012 10 Inviting Patients To Read Their Doctors’ Notes: A Quasi-experimental Study And A Look Ahead
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Abstract: Little information exists about what primary care physicians (PCPs) and patients experience if patients are invited to read their doctors’ office notes. To evaluate the effect on …		 TOM DELBANCO et. al.
2011 1 QUADAS-2: A Revised Tool For The Quality Assessment Of Diagnostic Accuracy Studies
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Abstract: In 2003, the QUADAS tool for systematic reviews of diagnostic accuracy studies was developed. Experience, anecdotal reports, and feedback suggested areas for improvement; …		 PENNY F WHITING et. al.
2011 2 Low Health Literacy And Health Outcomes: An Updated Systematic Review
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Abstract: Approximately 80 million Americans have limited health literacy, which puts them at greater risk for poorer access to care and poorer health outcomes. To update a 2004 systematic …		 Nancy D Berkman; Stacey L Sheridan; Katrina E Donahue; David J Halpern; Karen Crotty;
2011 3 Interventions To Reduce 30-day Rehospitalization: A Systematic Review
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Abstract: About 1 in 5 Medicare fee-for-service patients discharged from the hospital is rehospitalized within 30 days. Beginning in 2013, hospitals with high risk-standardized readmission …		 Luke O Hansen; Robert S Young; Keiki Hinami; Alicia Leung; Mark V Williams;
2011 4 Diagnosis And Management Of Stable Chronic Obstructive Pulmonary Disease: A Clinical Practice Guideline Update From The American College Of Physicians, American College Of Chest Physicians, American Thoracic Society, And European Respiratory Society
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Abstract: This guideline is an official statement of the American College of Physicians (ACP), American College of Chest Physicians (ACCP), American Thoracic Society (ATS), and European …		 AMIR QASEEM et. al.
2011 5 Comparative Effectiveness And Safety Of Medications For Type 2 Diabetes: An Update Including New Drugs And 2-drug Combinations
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Abstract: Given the increase in medications for type 2 diabetes mellitus, clinicians and patients need information about their effectiveness and safety to make informed choices. To …		 WENDY L BENNETT et. al.
2011 6 Screening For Prostate Cancer: A Review Of The Evidence For The U.S. Preventive Services Task Force
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Abstract: Screening can detect prostate cancer at earlier, asymptomatic stages, when treatments might be more effective. To update the 2002 and 2008 U.S. Preventive Services Task Force …		 ROGER CHOU et. al.
2011 7 Characteristics and Short-Term Prognosis of Perioperative Myocardial Infarction in Patients Undergoing Noncardiac Surgery
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Abstract: BACKGROUND Each year, millions of patients worldwide have a perioperative myocardial infarction (MI) after noncardiac surgery. OBJECTIVE To examine the characteristics and …		 P J DEVEREAUX et. al.
2011 8 Protection From Colorectal Cancer After Colonoscopy
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Abstract: BACKGROUND Colonoscopy with detection and removal of adenomas is considered a powerful tool to reduce colorectal cancer (CRC) incidence. However, the degree of protection …		 Hermann Brenner; Jenny Chang-Claude; Christoph M Seiler; Alexander Rickert; Michael Hoffmeister;
2011 9 Systematic Review: The Effect On Surrogates Of Making Treatment Decisions For Others
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Abstract: Clinical practice relies on surrogates to make or help to make treatment decisions for incapacitated adults; however, the effect of this practice on surrogates has not been …		 David Wendler; Annette Rid;
2011 10 Life Expectancy Of Persons Receiving Combination Antiretroviral Therapy In Low-income Countries: A Cohort Analysis From Uganda
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Abstract: Little is known about the effect of combination antiretroviral therapy (cART) on life expectancy in sub-Saharan Africa. To estimate life expectancy of patients once they initiate …		 EDWARD J MILLS et. al.
2010 1 CONSORT 2010 Statement: Updated Guidelines For Reporting Parallel Group Randomized Trials
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Abstract: The CONSORT (Consolidated Standards of Reporting Trials) statement is used worldwide to improve the reporting of randomized, controlled trials. Schulz and colleagues describe the …		 Kenneth F Schulz; Douglas G Altman; David Moher; D;
2010 2 International Consensus Recommendations On The Management Of Patients With Nonvariceal Upper Gastrointestinal Bleeding
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Abstract: A multidisciplinary group of 34 experts from 15 countries developed this update and expansion of the recommendations on the management of acute nonvariceal upper gastrointestinal …		 ALAN N BARKUN et. al.
2010 3 Opioid Prescriptions for Chronic Pain and Overdose
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Abstract: BACKGROUND Long-term opioid therapy for chronic noncancer pain is becoming increasingly common in community practice. Concomitant with this change in practice, rates of fatal …		 KATE M DUNN et. al.
2010 4 Meta-analysis: Excess Mortality After Hip Fracture Among Older Women And Men
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Abstract: Although an increased risk for death after hip fracture is well established, whether this excess mortality persists over time is unclear. To determine the magnitude and duration …		 PATRICK HAENTJENS et. al.
2010 5 Systematic Review: Vitamin D And Cardiometabolic Outcomes
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Abstract: Vitamin D may modify risk for cardiometabolic outcomes (type 2 diabetes, hypertension, or cardiovascular disease). To examine the association between vitamin D status, including …		 ANASTASSIOS G PITTAS et. al.
2010 6 Systematic Review: Vitamin D And Calcium Supplementation In Prevention Of Cardiovascular Events
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Abstract: Vitamin D and calcium may affect the cardiovascular system independently and interactively. To assess whether vitamin D and calcium supplements reduce the risk for cardiovascular …		 Lu Wang; JoAnn E Manson; Yiqing Song; Howard D Sesso;
2010 7 Systematic Review: Factors Associated With Risk For And Possible Prevention Of Cognitive Decline In Later Life
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Abstract: Many biological, behavioral, social, and environmental factors may contribute to the delay or prevention of cognitive decline. To summarize evidence about putative risk and …		 Brenda L Plassman; John W Williams; James R Burke; Tracey Holsinger; Sophiya Benjamin;
2010 8 The Spread Of Alcohol Consumption Behavior In A Large Social Network
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Abstract: Alcohol consumption has important health-related consequences and numerous biological and social determinants. To explore quantitatively whether alcohol consumption behavior …		 J Niels Rosenquist; Joanne Murabito; James H Fowler; Nicholas A Christakis;
2010 9 Cost-effectiveness Of Dabigatran Compared With Warfarin For Stroke Prevention In Atrial Fibrillation
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Abstract: Warfarin reduces the risk for ischemic stroke in patients with atrial fibrillation (AF) but increases the risk for hemorrhage. Dabigatran is a fixed-dose, oral direct thrombin …		 JAMES V FREEMAN et. al.
2010 10 Narrative Review: The Role Of Leptin In Human Physiology: Emerging Clinical Applications
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Abstract: Leptin is a hormone secreted by adipose tissue in direct proportion to amount of body fat. The circulating leptin levels serve as a gauge of energy stores, thereby directing the …		 Theodore Kelesidis; Iosif Kelesidis; Sharon Chou; Christos S Mantzoros;